Flexible wearable electrochemical biosensor

Abstract

The invention provides a flexible wearable electrochemical biosensor. The flexible wearable electrochemical biosensor comprises a working electrode, a reference electrode and an auxiliary electrode which are compounded together through weaving or second twisting. The working electrode, the reference electrode and the auxiliary electrode are all composed of conductive fibers and insulating wrapping fibers wrapping the surfaces of the conductive fibers, and biological sensitive active substances are fixed to the surfaces of the conductive fibers of the working electrode. One end of the working electrode, one end of the reference electrode and one end of the auxiliary electrode are electrically connected through a circuit; when sweat permeates into the conductive fibers from the insulating wrapping fibers, the working electrode, the reference electrode and the auxiliary electrode form a three-electrode conductive path, so that electrochemical sensing is achieved through signal changes of biological sensitive active substances of the working electrode. According to the flexible wearable electrochemical biosensor, the working electrode, the reference electrode and the auxiliary electrode which are of a core-spun structure are compounded together to prepare the integrated flexible wearable electrochemical biosensor, and sweat components can be rapidly, sensitively and accurately detected.

Description

technical field [0001] The invention relates to the technical field of electrochemical sensing, in particular to a flexible and wearable electrochemical biosensor. Background technique [0002] Sweat is a product of human metabolism, mainly composed of water, and also contains a small amount of sodium chloride, potassium chloride, calcium carbonate, lactic acid, uric acid, glucose, tyrosine and other substances. Studies have shown that the composition and content of sweat can provide a lot of information related to the physiological state of the human body, and the sensing and detection of sweat has great significance for clinical medicine, personal health monitoring, chronic disease prevention, reduction of medical costs, and relief of social medical resources. Significance. Non-invasive smart wearable electronic devices have become a research hotspot at home and abroad because they are portable, sensitive, flexible, and can work continuously. They can meet the current dev...

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Problems solved by technology

Although the protein film has good biocompatibility and can be in direct contact with the skin, it has a single structure and does not have the function of collecting and storing sweat

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