High-molecular polymer antibacterial material

A high-molecular polymer, antibacterial material technology, applied in surgery, medical science and other directions, can solve problems such as corrosion and secondary fractures

Pending Publication Date: 2021-11-16
斯凯优生物医疗科技苏州有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with ordinary absorbable bone screw materials, β-TCP / HA and drug-filled degradable plastics for absorbable bone screws provided by SKYU not only meet the basic characteristics of ordinary degradable plastics, but also provide some The advantages of other auxiliary features solve the problem that traditional metal bone screws will corrode during the long-term implantation process. Due to the difference in hardness with the bone and the stress effect, it will lead to osteoporosis, secondary fractures after surgery, and most It needs to be taken out twice, so that the patient will suffer from the second pain

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The macromolecular polymer antibacterial material that the present embodiment exemplifies, 30 parts of polyethylene terephthalates, 2 parts of slippery agents, 4 parts of inorganic antibacterial agents, 3 parts of quaternized bio-carbon antibacterial agents, aromatic heterocycle polymerization 6 5-8 parts, plastic additive 3 parts, heat stabilizer 5 parts, antioxidant 2 parts, latex 35 parts, chitosan fiber 0 parts, silica gel 10 parts.

[0021] In this embodiment, the material of the slip agent is silicon dioxide powder, and the central particle size is 1 μm-3 μm.

[0022] In this embodiment, the composition of the inorganic antibacterial agent is mainly silver ion antibacterial agent.

[0023] In this embodiment, the heat stabilizer is a stabilizer made by processing polyvinyl chloride and vinyl chloride copolymer.

[0024] In this example, the weighed polyethylene terephthalate, slip agent, plastic additive, heat stabilizer and antioxidant are poured into the mixer ...

Embodiment 2

[0031] The macromolecular polymer antibacterial material that the present embodiment exemplifies, 30 parts of polyethylene terephthalates, 2 parts of slippery agents, 4 parts of inorganic antibacterial agents, 3 parts of quaternized bio-carbon antibacterial agents, aromatic heterocycle polymerization 6 5-8 parts, plastic additive 3 parts, heat stabilizer 5 parts, antioxidant 2 parts, latex 0 parts, chitosan fiber 40 parts, silica gel 5 parts.

[0032] In this embodiment, the material of the slip agent is silicon dioxide powder, and the central particle size is 1 μm-3 μm.

[0033] In this embodiment, the composition of the inorganic antibacterial agent is mainly silver ion antibacterial agent.

[0034] In this embodiment, the heat stabilizer is a stabilizer made by processing polyvinyl chloride and vinyl chloride copolymer.

[0035] In this example, the weighed polyethylene terephthalate, slip agent, plastic additive, heat stabilizer and antioxidant are poured into the mixer a...

Embodiment 3

[0042] The macromolecular polymer antibacterial material that the present embodiment exemplifies, 30 parts of polyethylene terephthalates, 3 parts of slippery agents, 5 parts of inorganic antibacterial agents, 3 parts of quaternized bio-carbon antibacterial agents, aromatic heterocycle polymerization 6 5-8 parts, plastic additive 3 parts, heat stabilizer 5 parts, antioxidant 2 parts, latex 3 parts, chitosan fiber 0 parts, silica gel 40 parts.

[0043] In this embodiment, the material of the slip agent is silicon dioxide powder, and the central particle size is 1 μm-3 μm.

[0044] In this embodiment, the composition of the inorganic antibacterial agent is mainly silver ion antibacterial agent.

[0045] In this embodiment, the heat stabilizer is a stabilizer made by processing polyvinyl chloride and vinyl chloride copolymer.

[0046] In this example, the weighed polyethylene terephthalate, slip agent, plastic additive, heat stabilizer and antioxidant are poured into the mixer a...

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Abstract

The invention discloses a high-molecular polymer antibacterial material, which is prepared from the following ingredients in parts by weight: 20 to 30 parts of polyethylene glycol terephthalate, 1 to 3 parts of slipping agents, 3 to 5 parts of inorganic antibacterial agents, 2 to 6 parts of quaternized biological carbon antibacterial agents, 5 to 8 parts of aromatic heterocyclic polymers, 1 to 3 parts of plastic additives, 2 to 5 parts of heat stabilizers, 1 to 3 parts of antioxidants, 0 to 50 parts of latex, 0-50 parts of chitosan fiber and 0-50 parts of silica gel; the invention aims to provide the high-molecular polymer antibacterial material which can be customized into a sustained-release drug within several days for short-term requirements such as postoperative analgesia. For clinical treatment of long time such as chronic pain, the medicine can be designed to be an elution medicine as long as several months, and when the set time limit is reached, the problems that a traditional metal bone nail is corroded in the long-term implantation process, osteoporosis and postoperative secondary fracture are caused by the hardness difference and stress effect of the metal bone nail, and mostly, secondary taking-out is needed are solved.

Description

technical field [0001] The invention relates to the technical field of biomedical polymer materials, in particular to a polymer antibacterial material. Background technique [0002] Biomedical polymer materials play an indispensable role in local drug delivery and sustained release medical products. According to different drugs, corresponding biomedical polymers are developed as carriers and mixed with therapeutic drugs in a molten state. And according to the application requirements, it is made into a specific product shape, such as: film, fiber / patch, single film, microsphere, rod or coated on the surface of the device, placed on the designated treatment site, according to the designed release dose, in the Within the required time range, release slowly at a certain rate or gradually with the degradation of polymer materials, the local sustained release of therapeutic drugs targeting human tissues can enhance the treatment of various diseases, thereby targeting specific dis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06A61L31/02A61L31/04A61L31/14A61L31/16
CPCA61L31/06A61L31/028A61L31/022A61L31/048A61L31/042A61L31/14A61L31/16A61L2300/404A61L2300/104A61L2300/602C08L67/02C08L27/06C08L5/08
Inventor 黄超
Owner 斯凯优生物医疗科技苏州有限公司
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