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External medicine capable of resisting HPV infection and converting HPV positive into HPV negative and preparation method thereof

A technology of external medicine and negative conversion, applied in the field of medicine, can solve the problems of no therapeutic effect, immune preparations and interferon can not be effectively treated, achieve high inhibition rate and avoid the effect of liver first pass effect

Pending Publication Date: 2022-01-11
顾绍亚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current oral immune preparations and interferon cannot be effectively treated, that is to say, the existing drugs have no therapeutic effect

Method used

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  • External medicine capable of resisting HPV infection and converting HPV positive into HPV negative and preparation method thereof
  • External medicine capable of resisting HPV infection and converting HPV positive into HPV negative and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] An external medicine for resisting HPV infection and capable of turning HPV positive into negative, comprising the following raw materials in parts by weight:

[0030] 35 parts of hedgehog, 20 parts of frankincense, 15 parts of Angelica dahurica, 15 parts of cat's claw, 10 parts of rhubarb, 7 parts of xanthophyll, 8 parts of dried alum, and 3 parts of realgar. The preparation method comprises the following steps:

[0031] (1) Pretreatment of raw materials: Soak the raw materials of medicinal materials in clean water below 15°C for 2-5 minutes. Soak in NaCl solution for 30min;

[0032] (2) Partial extraction of raw materials: using CO 2 Supercritical extraction is used for extraction, the extraction temperature is 45-60°C, the extraction time is 50-180min, the extraction pressure is 20-45mpa, the extract is dried to 120 meshes, and the active ingredients are obtained for later use; the medicinal residues are dried in an oven at 45°C dry, spare;

[0033] (3) Extractin...

Embodiment 2

[0040] An external medicine for resisting HPV infection and capable of turning HPV positive into negative, comprising the following raw materials in parts by weight:

[0041] 20 parts of fat hedgehog, 10 parts of frankincense, 10 parts of Angelica dahurica, 10 parts of cat's claw, 5 parts of rhubarb, 5 parts of xanthophyll, 5 parts of dried alum, and 2 parts of realgar. The preparation method comprises the following steps:

[0042] (1) Pretreatment of raw materials: Soak the raw materials of medicinal materials in clean water below 15°C for 2-5 minutes. Soak in NaCl solution for 30min;

[0043] (2) Partial extraction of raw materials: using CO 2 Supercritical extraction is used for extraction, the extraction temperature is 45-60°C, the extraction time is 50-180min, the extraction pressure is 20-45mpa, the extract is dried to 120 meshes, and the active ingredients are obtained for later use; the medicinal residues are dried in an oven at 45°C dry, spare;

[0044] (3) Extrac...

Embodiment 3

[0051] An external medicine for resisting HPV infection and capable of turning HPV positive into negative, comprising the following raw materials in parts by weight:

[0052] 50 parts of fat hedgehog, 30 parts of frankincense, 20 parts of Angelica dahurica, 20 parts of cat's claw, 15 parts of rhubarb, 10 parts of xanthophyll, 10 parts of dried alum, and 5 parts of realgar. The preparation method comprises the following steps:

[0053] (1) Pretreatment of raw materials: Soak the raw materials of medicinal materials in clean water below 15°C for 2-5 minutes. Soak in NaCl solution for 30min;

[0054] (2) Partial extraction of raw materials: using CO 2 Supercritical extraction is used for extraction, the extraction temperature is 45-60°C, the extraction time is 50-180min, the extraction pressure is 20-45mpa, the extract is dried to 120 meshes, and the active ingredients are obtained for later use; the medicinal residues are dried in an oven at 45°C dry, spare;

[0055] (3) Ext...

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Abstract

The invention discloses an external medicine capable of resisting HPV infection and converting HPV positive to HPV negative and a preparation method thereof. The external medicine is prepared from the following raw materials in parts by weight: 20 to 50 parts of hedgehog fat, 10 to 30 parts of frankincense, 10 to 20 parts of radix angelicae, 10 to 20 parts of radix ranunculi ternati, 5 to 15 parts of radix et rhizoma rhei, 5 to 10 parts of airpotato yam rhizome, 5 to 10 parts of dried alum and 2 to 5 parts of realgar. Years of clinical experience prove that the medicine disclosed by the invention has no adverse reaction, the medicine can avoid the first-pass effect of the liver when being externally used, has a targeting effect, and has a higher inhibition rate on host cytopathy caused by HPV than that of immune preparations and interferon.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an external medicine for resisting HPV infection and capable of turning HPV positive into negative and a preparation method thereof. Background technique [0002] HPV is mainly transmitted through skin or mucous membrane contact. The virus can induce epithelial tissue hyperplasia and make it keratinized. Epithelial proliferation forms papillary tumors, called warts, and is also the direct cause of female cervical squamous cell carcinoma. However, the current oral immune preparations and interferon cannot be effectively treated, that is to say, the existing drugs have no therapeutic effect. Contents of the invention [0003] Aiming at the deficiencies in the prior art, an object of the present invention is to provide an external medicine for resisting HPV infection and turning HPV positive to negative. Another object of the present invention is to provide a prepara...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P31/20A61K35/35A61K33/06A61K33/36
CPCA61K35/35A61K36/324A61K36/232A61K36/71A61K36/708A61K36/8945A61K33/06A61K33/36A61K9/0034A61P31/20A61K2236/13A61K2236/37A61K2236/33A61K2236/39A61K2236/51A61K2236/331A61K2300/00
Inventor 顾绍亚
Owner 顾绍亚
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