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Anti-freezing agent for glycosylated hemoglobin kit and application method thereof

A technology of glycosylated hemoglobin and antifreeze, which is applied in the field of medical products, can solve the problems of affecting the measurement results, poor constant temperature effect, complex structure, etc., and achieve the effects of high hydrophilicity, improved compatibility, and high biocompatibility

Pending Publication Date: 2022-02-08
广西康柏莱科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to ensure effectiveness, the glycosylated hemoglobin assay kit requires special cold chain transportation, but large-scale cold chain transportation tools are complex in structure and extremely expensive, and are only suitable for large-scale transportation. , Waterproof, anti-shock, anti-aging and low-cost independent foam insulation box for storage and transportation. This storage and transportation method has poor constant temperature effect. During transportation, the temperature will be uneven due to vibration or extrusion, and even low-temperature freezing will occur; Or it is difficult to transport for a long time in high-latitude cold regions, resulting in the inactivation of the reagents in the kit, thus affecting the measurement results

Method used

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  • Anti-freezing agent for glycosylated hemoglobin kit and application method thereof
  • Anti-freezing agent for glycosylated hemoglobin kit and application method thereof
  • Anti-freezing agent for glycosylated hemoglobin kit and application method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Preparation of antifreeze: Weigh antifreeze raw materials, dissolve them in water, and configure antifreeze solutions containing the following mass concentration raw materials: 1mg / L trimethylammonium hydrochloride, 5mg / L methyl cellulose, 1mg / L L's 2-methacryloyloxyethyl phosphorylcholine.

Embodiment 2

[0028] Preparation of antifreeze: Weigh antifreeze raw materials, dissolve them in water, and configure an antifreeze solution containing the following mass concentration raw materials: trimethylammonium hydrochloride at 5 mg / L, glycerin at 5 mg / L, formazan at 1 mg / L Base cellulose, 5mg / L 2-methacryloyloxyethyl phosphorylcholine.

Embodiment 3

[0030] Preparation of antifreeze: Weigh antifreeze raw materials, dissolve them in water, and configure an antifreeze solution containing the following mass concentration raw materials: 2mg / L trimethylammonium hydrochloride, 2mg / L glycerin, 3mg / L formazan Base cellulose, 2mg / L 2-methacryloyloxyethyl phosphorylcholine.

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Abstract

The invention discloses an anti-freezing agent for a glycosylated hemoglobin kit and an application method thereof, and belongs to the technical field of medical products. The anti-freezing agent comprises the following components: trimethyl ammonium hydrochloride, glycerol, methyl cellulose and 2-methacryloyloxyethyl phosphorylcholine. The anti-freezing agent is used in the glycosylated hemoglobin kit and can resist low-temperature freeze thawing, the kit can be transported and stored at the temperature lower than -0 DEG C and repeatedly stored and taken for five times in the environment of -20 DEG C, the low-temperature stable preservation time is one month or above, and meanwhile the anti-freezin agent is high in detection sensitivity, high in specificity, good in precision and low in cost and can achieve accurate detection of glycosylated hemoglobin.

Description

technical field [0001] The invention belongs to the field of medical products and technologies, and in particular relates to an antifreeze used in a glycosylated hemoglobin kit and an application method thereof. Background technique [0002] Glycated hemoglobin (HbA1c) is the product of the combination of hemoglobin in red blood cells and carbohydrates in serum through non-enzymatic reactions. It is generally believed that the concentration of glycosylated hemoglobin can effectively reflect the average blood glucose level in the past 8 to 12 weeks. Scope of Application of Glycated Hemoglobin Determination Kit This kit is used for the quantitative determination of Glycated hemoglobin in serum or plasma in vitro. [0003] In order to ensure effectiveness, the glycosylated hemoglobin assay kit requires special cold chain transportation, but large-scale cold chain transportation tools are complex in structure and extremely expensive, and are only suitable for large-scale transpo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/72B65D81/18
CPCG01N33/723B65D81/18
Inventor 李名星张设熙莫智林韦佳志黄多全杨添源
Owner 广西康柏莱科技有限公司
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