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Micro liquid collector and use method

A liquid collection and micro-volume technology, which is applied in the field of medical devices, can solve the problems of difficult control of blood volume or body fluid, reduce collection efficiency, time-consuming and labor-intensive problems, and achieve the effect of easy control of absorption, improvement of experimental efficiency, and improvement of collection efficiency

Pending Publication Date: 2022-04-26
AFFILIATED HOSPITAL OF JINING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The advantage of this method is that it is easy to operate and does not need to kill the mice. The disadvantages are: (1) the operation is painful in vivo, which violates animal ethics; Large damage; (3) inconvenient multiple blood collection; (4) very easy to cause infection for immunodeficiency mice
At present, syringes are often used for micro-collection of blood or body fluids, but there are still the following problems: (1) the initial suction of the syringe is relatively large, the blood volume or body fluids are not easy to control, and it is very easy to cause blood flow interruption, such as tail vein It is very easy to cause the blood supply of the tail vein to be cut off during blood collection; (2) There is a buffer area between the needle and the liquid collection chamber, which makes the collection liquid unable to be completely taken out, resulting in unnecessary waste, unable to realize on-demand collection, and reducing collection efficiency , and increases the damage to the collected person, and the safety is low; (3) the existing syringe is used to take the liquid by pulling, and the length is generally more than 8cm, and it is difficult to perform single-handed operation when sampling from a living body , often requires the cooperation of two people, which is time-consuming and labor-intensive

Method used

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  • Micro liquid collector and use method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] like figure 1 As shown, the micro-liquid sampler 100 provided in this embodiment includes a first cavity 1, a second cavity 2 and a needle 3, and one end of the first cavity 1 with an opening is fixedly connected to one end of the second cavity 2 and It should be noted that only one end of the first cavity 1 is provided with an opening, the other end of the second cavity 2 is connected and communicated with one end of the needle 3, and the end surface of the needle 3 close to the second cavity 2 is connected to the second cavity The inner cavity of the needle 2 is coplanar with the end surface of the needle 3, so that the collection liquid can be completely taken out, which is conducive to the realization of on-demand collection, thereby improving the collection efficiency, and can reduce the damage to the collected person, which is conducive to improving the safety of collection; The first cavity 1 can provide negative pressure for the second cavity 2 by being squeezed...

Embodiment 2

[0033] The method for using the micro-liquid sampling device 100 in Example 1 provided in this embodiment includes the following steps:

[0034] S1. Use the index finger and middle finger to clamp the second cavity 2, and use the thumb and ring finger to squeeze the first cavity 1, so that the gas in the first cavity 1 and the second cavity 2 is discharged from the needle 3, and the first cavity Cavity 1 remains in a deformed state;

[0035] S2. Insert the needle 3 into the blood vessel or tissue, and slowly release the thumb and ring finger. One-handed operation is possible.

[0036] S1 also includes:

[0037]According to the amount of fluid collected, the squeezing strength of the thumb and the ring finger to the first cavity 1 or the degree of release of the thumb and the ring finger are determined. After sampling is completed, the sample can be transferred to other containers by squeezing the first cavity 1 . It should be noted that the maximum pressure that the first ...

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Abstract

The invention discloses a trace liquid collector, which relates to the technical field of medical apparatus and instruments, and comprises a first cavity, a second cavity and a needle head, one end of the first cavity, which is provided with an opening, is fixedly connected and communicated with one end of the second cavity, and the other end of the second cavity is connected and communicated with one end of the needle head; the end face, close to the second cavity, of the needle head and the end face, close to the needle head, of an inner cavity of the second cavity are coplanar, and the first cavity can provide negative pressure for the second cavity through extrusion deformation and suck liquid into the inner cavity of the second cavity through the needle head. The invention further discloses a using method of the trace liquid collector, which comprises the following steps: S1, clamping the second cavity by using the index finger and the middle finger, and extruding the first cavity by using the thumb and the ring finger, so that gas in the first cavity and the second cavity is discharged by the needle head, and the first cavity is kept in a deformed state; s2, inserting the needle into a blood vessel or tissue, and slowly loosening the thumb and the ring finger. The operation is convenient, and the acquisition efficiency and the acquisition safety can be improved.

Description

technical field [0001] The invention relates to the technical field of medical instruments, in particular to a micro-liquid sampling device. Background technique [0002] In clinical testing, it is often necessary to collect blood or body fluids such as cerebrospinal fluid, abscess fluid, and peritoneal fluid according to different inspection items. Among them, blood is the most commonly used test specimen in scientific research. Taking mice as an example, in animal experiments, commonly used blood collection methods include tail vein blood collection, orbital venous plexus blood collection, eyeball blood collection and heart blood collection. Among them, the tail vein blood collection and the orbital venous plexus blood collection are living blood collections. A small amount of blood collection generally uses tail vein blood collection. The traditional blood collection method is: cut off the tip of the tail about 0.2cm-0.3cm, and then quantitatively absorb the tail blood wi...

Claims

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Application Information

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IPC IPC(8): A61B10/00A61B5/151A61B5/15A61B5/153
CPCA61B10/0045A61B5/151A61B5/150427A61B5/150251A61B5/150755A61B5/153A61B2010/0077A61B2503/40
Inventor 张现宁陈明台刘路路
Owner AFFILIATED HOSPITAL OF JINING MEDICAL UNIV
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