Flexible sweat and sugar electrochemical sensor

Abstract

The invention provides a flexible sweat-sugar electrochemical sensor. The flexible sweat-sugar electrochemical sensor comprises a flexible substrate, and a glucose sensing electrode, a reference electrode and a counter electrode which are arranged on the surface of the flexible substrate. The glucose sensing electrode is prepared by directly dispensing electrode modification liquid containing multi-walled carbon nanotubes, Prussian blue nanoparticles and glucose oxidase on the surface of a flexible gold electrode. Glucose oxidase on a glucose sensing electrode is utilized to oxidize glucose in sweat, generated hydrogen peroxide reacts with Prussian blue nanoparticles to generate a current signal on the electrode, and then quantitative analysis is performed on the glucose in the sweat based on a standard curve method. The flexible sweat and sugar electrochemical sensor provided by the invention has the advantages of simplicity in preparation, low cost, good product performance, suitability for large-scale production and the like, and has a good application prospect in the field of development of wearable sweat and sugar sensors.

Description

1. Technical field [0001] The invention relates to the technical field of electrochemical sensors, in particular to a flexible sweat sugar electrochemical sensor. 2. Background technology [0002] Diabetes is one of the most common metabolic disorders, which can cause various complications, such as cardiovascular and cerebrovascular diseases, renal failure and so on. At present, the monitoring of diabetes mainly relies on blood glucose measurement at fixed times, but high-frequency blood collection will bring great pressure to the patient's body and mind. Although the recently developed wearable continuous glucose monitoring device has the advantages of small size, easy to carry, and can be attached to the body for real-time monitoring of human blood glucose, there are still risks of infection caused by wearing discomfort, skin allergies, and invasive sampling. [0003] Studies have found that the glucose content levels in various human metabolic fluids such as sweat, saliv...

AI Technical Summary

Problems solved by technology

Recently, combined with the development of electronic information and other fields, a variety of wearable sweat biosensors have been proposed and used for real-time detection of glucose in sweat. Although these designs have good intelligence and user applicability, the preparation of these glucose sensors often Including electroplating, multi-step drop coating, etc., it is not suitable for its commercial production, so it is still in the stage of laboratory research and development and conceptual design

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