Flexible sweat and sugar electrochemical sensor

An electrochemical and sensor technology, applied in the field of flexible sweat sugar electrochemical sensors, can solve problems such as inappropriate product production, and achieve the effects of ensuring stability, simple process, and controllable size

Pending Publication Date: 2022-05-13
NANJING UNIV
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Problems solved by technology

Recently, combined with the development of electronic information and other fields, a variety of wearable sweat biosensors have been proposed and used for real-time detection of glucose in sweat. Although these designs have good intelligence and user app

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  • Flexible sweat and sugar electrochemical sensor
  • Flexible sweat and sugar electrochemical sensor

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Embodiment Construction

[0017] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are the preferred embodiments of the present invention, and are only used to explain the present invention, not to limit the present invention.

[0018] The invented flexible sweat glucose electrochemical sensor comprises a flexible substrate and a glucose sensing electrode, a reference electrode and a counter electrode ( figure 1 ).

[0019] The preparation process of the invented flexible sweat sugar electrochemical sensor includes the preparation of the flexible electrode, the preparation of the electrode modification solution and its modification.

[0020] The flexible electrode is prepared by electron beam evaporation: on the PET with a thickness of 100 μm, using different met...

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Abstract

The invention provides a flexible sweat-sugar electrochemical sensor. The flexible sweat-sugar electrochemical sensor comprises a flexible substrate, and a glucose sensing electrode, a reference electrode and a counter electrode which are arranged on the surface of the flexible substrate. The glucose sensing electrode is prepared by directly dispensing electrode modification liquid containing multi-walled carbon nanotubes, Prussian blue nanoparticles and glucose oxidase on the surface of a flexible gold electrode. Glucose oxidase on a glucose sensing electrode is utilized to oxidize glucose in sweat, generated hydrogen peroxide reacts with Prussian blue nanoparticles to generate a current signal on the electrode, and then quantitative analysis is performed on the glucose in the sweat based on a standard curve method. The flexible sweat and sugar electrochemical sensor provided by the invention has the advantages of simplicity in preparation, low cost, good product performance, suitability for large-scale production and the like, and has a good application prospect in the field of development of wearable sweat and sugar sensors.

Description

1. Technical field [0001] The invention relates to the technical field of electrochemical sensors, in particular to a flexible sweat sugar electrochemical sensor. 2. Background technology [0002] Diabetes is one of the most common metabolic disorders, which can cause various complications, such as cardiovascular and cerebrovascular diseases, renal failure and so on. At present, the monitoring of diabetes mainly relies on blood glucose measurement at fixed times, but high-frequency blood collection will bring great pressure to the patient's body and mind. Although the recently developed wearable continuous glucose monitoring device has the advantages of small size, easy to carry, and can be attached to the body for real-time monitoring of human blood glucose, there are still risks of infection caused by wearing discomfort, skin allergies, and invasive sampling. [0003] Studies have found that the glucose content levels in various human metabolic fluids such as sweat, saliv...

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Application Information

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IPC IPC(8): G01N27/327
CPCG01N27/3272
Inventor 鞠熀先吴洁于倩
Owner NANJING UNIV
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