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Microfluidic thrombus elasticity analysis and detection kit

A detection kit and thromboelasticity technology, applied in biological testing, material testing products, laboratory containers, etc., can solve the problems of bulky, high cost, complicated instruments, etc., and achieve reduced volume, simple structure, and scientific design. reasonable effect

Pending Publication Date: 2022-05-31
四川微康朴澜医疗科技有限责任公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional thrombelastograph is not only complex in structure, but also bulky and expensive
[0006] Therefore, designing a microfluidic thromboelastometry detection kit to overcome the technical defects of the thromboelastography instrument such as complexity, bulkiness, and high cost has become a technical problem to be solved urgently by technicians in the technical field.

Method used

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  • Microfluidic thrombus elasticity analysis and detection kit
  • Microfluidic thrombus elasticity analysis and detection kit
  • Microfluidic thrombus elasticity analysis and detection kit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1, such as Figure 1-4 As shown, a microfluidic thrombus elasticity analysis detection kit 5 provided by the present invention includes a kit body 1 and a kit sealing plate 3 packaged on the kit body 1, and the kit body 1 is provided with a sample reagent The mixing chamber 1-2, the overflow chamber 1-7 connected from the sample reagent mixing chamber 1-2, and the droplet motion detection channel 1-9 connected from the overflow chamber 1-7, the sample reagent mixing chamber Freeze-dried reagent balls 2 are provided in the homogenization chamber 1-2, and the kit sealing plate 3 is provided with a sample reagent mixing chamber 1-2 for filling whole blood samples into the sample reagent mixing chamber 1-2. Sample filling port 3-1.

[0029] The invention has the advantages of simple structure, scientific and reasonable design, and convenient use. The designed microfluidic kit can make the structure of the thromboelastography instrument simpler, effectively reduce t...

Embodiment 2

[0030] Example 2, such as Figure 1-4 As shown, a microfluidic thrombus elasticity analysis detection kit 5 provided by the present invention includes a kit body 1 and a kit sealing plate 3 packaged on the kit body 1, and the kit body 1 is provided with a sample reagent The mixing chamber 1-2, the overflow chamber 1-7 connected from the sample reagent mixing chamber 1-2, and the droplet motion detection channel 1-9 connected from the overflow chamber 1-7, the sample reagent mixing chamber Freeze-dried reagent balls 2 are provided in the homogenization chamber 1-2, and the kit sealing plate 3 is provided with a sample reagent mixing chamber 1-2 for filling whole blood samples into the sample reagent mixing chamber 1-2. Sample filling port 3-1. The main body 1 of the kit is provided with a low-speed sealing port 1-5 connected to the sample reagent mixing chamber 1-2, and a high-speed conduction channel 1-5 is connected between the overflow chamber 1-7 and the low-speed sealing ...

Embodiment 3

[0032] Example 3, such as Figure 1-4As shown, a microfluidic thrombus elasticity analysis detection kit 5 provided by the present invention includes a kit body 1 and a kit sealing plate 3 packaged on the kit body 1, and the kit body 1 is provided with a sample reagent The mixing chamber 1-2, the overflow chamber 1-7 connected from the sample reagent mixing chamber 1-2, and the droplet motion detection channel 1-9 connected from the overflow chamber 1-7, the sample reagent mixing chamber Freeze-dried reagent balls 2 are provided in the homogenization chamber 1-2, and the kit sealing plate 3 is provided with a sample reagent mixing chamber 1-2 for filling whole blood samples into the sample reagent mixing chamber 1-2. Sample filling port 3-1. The main body 1 of the kit is provided with a low-speed sealing port 1-5 connected to the sample reagent mixing chamber 1-2, and a high-speed conduction channel 1-5 is connected between the overflow chamber 1-7 and the low-speed sealing p...

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Abstract

The invention discloses a microfluidic thrombelastogram analysis and detection kit, and solves the technical problems of complex structure, large volume and high production cost of a thrombelastogram instrument in the prior art. The kit comprises a kit main body and a kit sealing plate packaged on the kit main body, the kit main body is provided with a sample reagent uniform mixing bin, an overflow bin connected out of the sample reagent uniform mixing bin and a liquid drop movement detection flow channel connected out of the overflow bin, and freeze-drying reagent balls are arranged in the sample reagent uniform mixing bin. And the kit sealing plate is provided with a sample filling port which is communicated with the sample reagent mixing bin and is used for filling a whole blood sample into the sample reagent mixing bin. The microfluidic kit is simple in structure, scientific and reasonable in design and convenient to use, the structure of the thrombelastogram instrument can be simpler through the designed microfluidic kit, the size of the thrombelastogram instrument can be effectively reduced, the manufacturing cost of the thrombelastogram instrument can be reduced, and miniaturization and integration development of the thrombelastogram instrument can be powerfully promoted.

Description

technical field [0001] The invention belongs to the technical field of medical equipment, and in particular relates to a microfluidic thrombus elasticity analysis and detection kit. Background technique [0002] Thromboelastogram (thromboela-stogram, TEG) is an index that reflects the dynamic changes of blood coagulation (including the formation speed of fibrin, the dissolution state, the solidity of coagulation, and the elasticity). Therefore, the main factors affecting thromboelastogram are: red blood cells The state of aggregation, the rigidity of red blood cells, the speed of hemagglutination, the activity of the fibrinolytic system, etc. [0003] Thromboelastogram (TEG) is a special graph drawn by thromboelastometry. The main components of the elastometer; the stainless steel blood cup that automatically adjusts the constant temperature (37°C), the small stainless steel cylinder inserted into the cup, and the sensor that can be connected to the cylinder. The blood cup...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00B01F33/30B01F29/00G01N33/86B01F101/23
CPCB01L3/5027G01N33/86B01L2200/10
Inventor 唐勇廖政潘颖罗帅
Owner 四川微康朴澜医疗科技有限责任公司