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Shenqi extraction concentrated solution, Shenqi oral liquid and preparation method thereof

A technology of Shenqi oral liquid and concentrated liquid, which is applied in the field of medicine, can solve the problems of being unsuitable for diabetic patients, have a beany smell, poor clarity and the like, and achieves the transfer rate of astragaloside IV, an index component of Shenqi extraction concentrate. The effect of maintaining stability and good clarity

Active Publication Date: 2022-08-02
中山市恒生药业有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to overcome the disadvantages or deficiencies of Shenqi oral liquid in the prior art, such as poor clarity, beany smell, and not suitable for diabetic patients, and to provide a concentrated extract of Shenqi

Method used

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  • Shenqi extraction concentrated solution, Shenqi oral liquid and preparation method thereof
  • Shenqi extraction concentrated solution, Shenqi oral liquid and preparation method thereof
  • Shenqi extraction concentrated solution, Shenqi oral liquid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] In this example, the preparation process of the Shenqi extract concentrate is optimized, so as to improve the clarity of the Shenqi oral solution, and at the same time achieve a more optimized impurity removal effect and purification of active ingredients such as astragaloside IV.

[0053] Specifically, a series of optimizations are carried out on the basis of Embodiment 1 of patent CN102441027A, and the operations are as follows:

[0054] Control group (refer to CN102441027A embodiment 1): Codonopsis 187.5g, Astragalus 187.5, add 10 times of water for the first time, decoct for 4 hours; add 8 times of water for the second time, decoct for 4 hours; add 8 times of water for the third time , decocted for 4 hours; the combined filtrate was concentrated to 800±20mL, left standing, and filtered. The content and transfer rate of astragaloside IV were determined.

[0055] Test group 1: Codonopsis 187.5g, Astragalus 187.5, add 10 times the amount of water for the first time, and...

Embodiment 2～8

[0066] This embodiment provides a series of Shenqi oral liquid, and its formula is shown in Table 3. The corresponding Shenqi extract concentrates (test groups 4-6) were prepared according to the same or basically the same method as test group 3, and the feeding ratio of Codonopsis and Astragalus was 1:1. The specific conditions and test results are shown in Table 2.

[0067] Table 2 The measurement results of each test group extracting the concentrate

[0068]

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Abstract

The invention relates to a ginseng-astragalus extract concentrated solution, a ginseng-astragalus oral solution and a preparation method and application thereof. The preparation method of the ginseng and astragalus extract concentrated solution comprises the steps of extraction, concentration, boiling, low-temperature standing, centrifugation and the like. According to the radix codonopsis and radix astragali extraction concentrated solution provided by the invention, through optimization of an extraction and concentration process, leaching of non-medicinal substances with poor water solubility, such as phlegm and starch, is reduced, meanwhile, removal of the non-medicinal substances with poor water solubility, such as phlegm and starch, is enhanced, and the transfer rate of an index component astragaloside in the obtained radix codonopsis and radix astragali extraction concentrated solution is kept stable; meanwhile, the ginseng-astragalus oral liquid prepared from the ginseng-astragalus oral liquid has better clarity.

Description

technical field [0001] The invention belongs to the technical field of medicine, and particularly relates to a Shenqi extract concentrate, a Shenqi oral liquid and a preparation method and application thereof. Background technique [0002] Shenqi Oral Liquid is a Chinese patent medicine with the function of invigorating Qi and strengthening the body. It is used for the treatment of weak Qi and limb weakness. The existing Shenqi oral liquid preparation method (CN102441027A) is to take Codonopsis pilosula, astragalus two flavors and add water to decoct three times, add 10 times of water for the first time, add 8 times of water for the second time and the third time, and decoct 4 times each time. hours, combine the decoction, filter, concentrate the filtrate to about 800ml, stand, filter, add 154.6g of simple syrup and 2g of potassium sorbate to the filtrate, stir to dissolve, add water to adjust the total amount to 1000ml, stir well, filter Fill, sterilize, and get ready. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K47/26A61K36/481A61P39/00
CPCA61K9/0095A61K47/26A61K36/344A61K36/481A61P39/00A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00Y02A40/90
Inventor 乔卫林劳悦富唐琳陈炜璇赵雪婷彭丽华李海燕陆如满陈金梅黄愉锋
Owner 中山市恒生药业有限公司