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Pharmaceutical composition containing immunity enhancing drug effect material basis of astragalus membranaceus and glossy privet fruit immunity enhancing particles as well as preparation method and application of pharmaceutical composition

A composition and drug technology, applied in the field of Chinese veterinary medicine, to achieve the effects of controllable quality, clear chemical structure and fixed components

Pending Publication Date: 2022-08-05
沈阳伟嘉生物技术有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there is no relevant research on the material basis of the immune-enhancing efficacy of "Qizhen Zengmian Granules"

Method used

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  • Pharmaceutical composition containing immunity enhancing drug effect material basis of astragalus membranaceus and glossy privet fruit immunity enhancing particles as well as preparation method and application of pharmaceutical composition
  • Pharmaceutical composition containing immunity enhancing drug effect material basis of astragalus membranaceus and glossy privet fruit immunity enhancing particles as well as preparation method and application of pharmaceutical composition
  • Pharmaceutical composition containing immunity enhancing drug effect material basis of astragalus membranaceus and glossy privet fruit immunity enhancing particles as well as preparation method and application of pharmaceutical composition

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Experimental program
Comparison scheme
Effect test

Embodiment

[0040] 1. Preparation of effective parts of various extracts of "Qizhen Zengmai Granules"

[0041] Take a 10g sample of "Qizhen Zengmai Granules", and perform reflux extraction with 75% ethanol solution for a total of three times (the ratio of material to liquid is 1:10, 1:12, and 1:12; each extraction time is 2h), and the pressure is reduced. Concentrated acid to thick extract, weighed. Disperse the total extract with water to a fully dissolved state (the amount of alcohol added should not exceed 10% of the total system). After passing through D101 macroporous resin, eluting with different concentrations of ethanol solution, collecting the water section, 10%, 30%, 50%, 80%, 95% of the eluted parts were concentrated, evaporated to dryness, weighed, and used for later use.

[0042] "Qizhen Zengmai Granules" is produced by Shenyang Weijia Biotechnology Co., Ltd. and consists of 180kg of Astragalus lucidum 90kg and 90kg of Epimedium Concentrate to a clear paste with a relative ...

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Abstract

The invention belongs to the technical field of traditional Chinese veterinary medicines, and particularly relates to a pharmaceutical composition containing an immunity enhancing drug effect material basis of astragalus membranaceus and glossy privet immunity enhancing particles as well as a preparation method and application of the pharmaceutical composition. The pharmaceutical composition is prepared from one or more of the following components: astragaloside, quercetin, lupeol, rutin, apigenin-7-O-beta-D-glucoside, salidroside or ligustrum acid. The pharmaceutical composition for enhancing the immunity of livestock and poultry has the advantages of clear pharmacodynamic material basis, clear chemical structure, fixed components and controllable quality, and lays a foundation for the safety and effectiveness of the traditional Chinese medicine active component composition.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese veterinary medicine, and in particular relates to a pharmaceutical composition containing the immune-enhancing medicinal effect material basis of Qizhen Zengmai granules, and a preparation method and application thereof. Background technique [0002] Qizhen Zengmai Granules have been included in the national standard and are a veterinary drug commonly used in clinical practice to treat low immunity of livestock and poultry. Its main components include Astragalus, Epimedium and Ligustrum lucidum. Qi and solid table as the main medicine, Epimedium tonifying kidney and strengthening Yang, Ligustrum lucidum nourishing yin and tonifying kidney, nourishing liver and improving eyesight. [0003] At present, some scholars have investigated the regulating effect of Qizhen Zengmai Granule on immune cytokines in normal mice, and the results show that it can significantly increase the secretion of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/638A61K9/16A61K31/7048A61P37/04A61K31/352A61K31/56A61K31/7032
CPCA61K36/481A61K36/296A61K36/638A61K31/7048A61K31/352A61K31/56A61K31/7032A61K9/1652A61K9/1623A61P37/04A61K2236/333A61K2236/55A61K2236/39A61K2300/00Y02A40/70
Inventor 闫琰卢迪王方孙悦赵宝凯齐六卫王大成
Owner 沈阳伟嘉生物技术有限公司
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