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Application of conjugated carbon-iodine polymer to preparation of radiotherapy positioning patch

A radiation therapy and polymer technology, applied in the direction of X-ray/γ-ray/particle irradiation therapy, etc., can solve the problems of poor biocompatibility, unstable relative position, and low quality of positioning ball imaging, so as to achieve easy identification , Simple structure, good plasticity

Pending Publication Date: 2022-08-05
HUAZHONG UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The invention solves the technical problems of low imaging quality, unstable relative position and poor biocompatibility in the prior art. The invention provides a polydiacetylene (PDA) main chain, Conjugated polymers with only iodine atom substituents, and methods of synthesis and use in vivo labeling to guide precise surgical resection and radiation therapy

Method used

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  • Application of conjugated carbon-iodine polymer to preparation of radiotherapy positioning patch
  • Application of conjugated carbon-iodine polymer to preparation of radiotherapy positioning patch
  • Application of conjugated carbon-iodine polymer to preparation of radiotherapy positioning patch

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] refer to figure 1 and figure 2 , the radiotherapy positioning sticker is a rectangular structure, and the positioning sticker is a 3cm x 2cm rectangular structure. The base layer sticker 1 is provided with a first scale line 2 and a second scale line 3, and the two scale lines are perpendicular to the center position of the base layer sticker. The diameter is between 2 and 2.5 mm.

[0032] The interior of the base layer sticker 1 is provided with a self-adhesive separation sticker 7, and the adhesives used are all nano-adhesives. The base sticker 1 is engraved with a plurality of circular lines with dense centers and sparsely arranged edges as scale indicator lines, and the first scale line 2 and the second scale line 3 appear blue and red under fluorescence. There is a fixed layer 6 at the very top.

[0033] The first scale line 2 is a centimeter scale line, and the second scale line 3 is a millimeter scale line.

[0034] Working principle: Before the patient rec...

Embodiment 2

[0036] refer to image 3 and Figure 4 , the radiotherapy positioning sticker is a rectangular structure, and the positioning sticker is a 3cm x 2cm rectangular structure. The top of the base sticker 1 is provided with a vertically arranged fluorescent sticker 2, the fluorescent sticker 2 is provided with a first scale line 3, the phosphorescent sticker 9 is located on the fluorescent sticker 2, and the phosphorescent sticker 9 is provided with a second scale line 8, and The positions of the phosphorescent stickers 9 and the fluorescent stickers 2 correspond to each other, and the PIDA cluster 4 is adhered to the center position of the base sticker 1, and the diameter of the PIDA cluster 4 is between 2-2.5 mm.

[0037] The interior of the base layer sticker 1 is provided with a self-adhesive separation sticker 7, and the adhesives used are all nano-adhesives. The top of the base layer sticker 1 is depicted with a plurality of round lines with dense centers and sparsely arran...

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Abstract

The invention relates to a conjugated carbon-iodine polymer and preparation thereof, and an application of the conjugated carbon-iodine polymer in preparation of a radiotherapy positioning patch, and belongs to the technical field of imaging markers. The invention discloses a radiotherapy positioning patch, which is used for positioning an irradiated focus part in a radiotherapy process and comprises a base layer patch, a conjugated carbon-iodine polymer cluster and a fixed layer, the surface of the base layer sticker is provided with fluorescent stickers which are parallel to the long and short edges of the base layer sticker and are perpendicular to each other, and the fluorescent stickers are concentric circle scale indication lines with dense inside and sparse outside; a fluorescent paste is pasted on the positioning paste, a first scale mark is arranged on the fluorescent paste, a phosphorescent paste is also pasted on the fluorescent paste, a second scale mark is arranged on the phosphorescent paste, and a conjugated carbon-iodine polymer (PIDA) cluster is pasted at the central position of the positioning paste. The positioning paste is pasted and fixed by using nano glue, the base layer paste is a transparent nano double-sided adhesive, and the fixing layer is a transparent nano single-sided adhesive.

Description

technical field [0001] The invention belongs to the technical field of imaging markers, and more particularly relates to a conjugated carbon iodine polymer and its preparation and application for preparing a radiotherapy positioning sticker. Background technique [0002] Radiation therapy uses the energy of radiation to destroy cell chromosomes so that cells cannot grow and kill rapidly proliferating tumor cells. Radiation therapy has become one of the main means of treating malignant tumors. Modern radiotherapy technology has the characteristics of accurate positioning, accurate planning, accurate positioning, and accurate irradiation. Accurate radiotherapy requires high positioning accuracy. The Radiation Therapy Positioning Ball facilitates alignment of the tumor area during radiation therapy. However, the imaging effect of the existing positioning stickers is not good, the positioning is not accurate enough, and it is easy to generate positioning errors, which makes th...

Claims

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/1029
Inventor 罗亮殷明明赵苒婷李佳翼刘若琳孟凡玲刘小明
Owner HUAZHONG UNIV OF SCI & TECH
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