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Chip micro flow electroosmosis pump

An electroosmotic pump and chip technology, which is applied in the field of micro-infusion and low-pressure micro-flow infusion pumps, can solve the problems of difficult to accurately deliver the flow rate, and does not solve the problems of removing air bubbles and forming air bubbles.

Inactive Publication Date: 2005-03-30
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

More importantly, Paul's patent does not solve the problem of eliminating air bubbles: when electric drive occurs, the electrochemical process on the electrode surface will always generate gas, and air bubbles will form after a little longer time
Due to the micro-leakage of the valve and dynamic seal of the traditional piston mechanical infusion pump, its leakage is within 10 -1 -1μL / min level, so it is difficult to accurately deliver the flow rate of less than μL / min level, which cannot meet the stringent requirements of microsystems

Method used

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  • Chip micro flow electroosmosis pump
  • Chip micro flow electroosmosis pump
  • Chip micro flow electroosmosis pump

Examples

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Effect test

Embodiment 1

[0036] Example 1: Single-stage filling channel pump, copper plate electrode, using silica gel filler with a filling channel length of 2.0 cm, an equivalent inner diameter of 75 μm, and an inner particle size of 1 μm, an equivalent inner diameter of an etched microchannel of 10 μm, and an aqueous solution with a pH value of 7.0. Driving voltage 130-200V, flow range 0.1-0.4nL / min, output pressure 0.3-3kPa;

Embodiment 2

[0037] Embodiment 2: Two-stage filling channel pump, stainless steel plate electrode, using silica gel filler with a filling channel length of 2.0 cm, an equivalent inner diameter of 200 μm, and an inner particle size of 1 μm, and an etched microchannel with an equivalent inner diameter of 5 μm, and the remaining conditions are the same as in Example 1. Driving voltage 80-150V, flow range 0.3-2.5nL / min, output pressure 0.1-1.5KPa;

Embodiment 3

[0038] Example 3: Eight-segment filling channel pump, crossing gold plate electrode, using filling channel length 0.5cm, inner filling equivalent inner diameter 100 μm, particle size 1 μm inner molding filler, etching microchannel equivalent inner diameter 10 μm, driving voltage 30-50V, Flow range 0.2-0.5nL / min, output pressure 0.1-5KPa.

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Abstract

A low-pressure microflow liquid delivery pump is characterized by that the fluid is directly driven by electric energy and the output pressure and flow of fluid can be regulated by controlling voltage and the length of filled channel or combination of channels. A gas remover is serially connected to the output of said pump. The rigid insulating material or semiconductor material with equivalent internal diameter of 1-1000 microns is used for filled microchannel. The planar or developed electrode is used. Its duct is (0.1-100)-micron capillary tube. Its drive voltage is 5-200 VDC. Its output pressure is 0.01-700 KPa. Its flow can be precisely regulated.

Description

technical field [0001] The invention relates to an electroosmotic flow-driven transfusion pump designed and manufactured on a chip, which is a low-pressure micro-flow transfusion pump with controllable flow of fluid directly driven by electric energy. It is mainly suitable for the liquid drive of the micro-flow system, especially the micro-infusion in the field of micro-total analysis system (μ-TAS), clinical medicine and so on. Background technique [0002] In 1803, Peucc did an experiment on electroosmosis. He managed to fix clay in a "U"-shaped tube, and the medium (water) moved toward the negative electrode when electrified. In 1809, Reuss also noticed the phenomenon of electroosmosis, that is, the phenomenon that the liquid moves relative to the charged tube wall under the action of a direct current electric field. Under the action of an external electric field, the dispersion medium moves through a porous membrane or a very fine capillary (radius 1-10nm), that is, the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01D61/46
Inventor 关亚风陈令新
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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