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Ginkgo leaf extract and its extracting method

An extraction method and extract technology, applied in the field of traditional Chinese medicine preparation, can solve the problems of lack of industrialization conditions, unreasonable process route, low total amount of active ingredients, etc., and achieve the effects of low production cost, high extraction rate, and reasonable process route.

Active Publication Date: 2007-05-16
AOLING BODA MEDICINE SCI & TECH DEV BEIJING
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  • Summary
  • Abstract
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AI Technical Summary

Problems solved by technology

The main problems in the existing technology: the total amount of active ingredients extracted is not high, the process route is not reasonable enough, or the industrialization conditions are not available, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0015] Preparation of Ginkgo biloba extract of the present invention

[0016] Ginkgo biloba is used as raw material. Ginkgo biloba leaves are picked in autumn when they are still green, removed from impurities, and dried in the sun. The selected ginkgo leaves contain more than 0.85% of total flavonol glycosides and more than 0.25% of total terpene lactones.

[0017] The preparation method is as follows:

[0018] 1. Extraction: crush the dried ginkgo leaves to 10-20 mesh, extract several times with 65-85% ethanol, combine the extracts, filter, recover ethanol, and concentrate to a thick paste.

[0019] The influence of ginkgo leaf fineness on the extraction effect is that too fine crushing will not only increase impurities, but also affect the proposal of total flavonol glycosides and total terpene lactones. It is more suitable to use 10-20 mesh broken leaves for extraction. The particle size range of ginkgo leaves determined by the present invention is It is 10-20 mesh.

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Abstract

The present invention belongs to the field of Chinese medicine preparing technology. The ginkgo leaf extract has total flavone and total terpene lactone content over 80 %, total flavone content over 70 %, flavonoid glycoside content over 40 % and total terpene lactone content over 10 %. The extraction process includes the following steps: extracting, purifying and separating, concentration, drying, etc. Compared with available technology, the present invention has the advantages of reasonable technological path, being suitable for industrial production, low production cost, high extracting rate of effective components, etc. The present invention also discloses the infusion liquid and powder for injection with the ginkgo leaf extract and their preparation process. The ginkgo leaf extract has wide application in medicine for treating cardiac vascular diseases.

Description

technical field [0001] The invention relates to a ginkgo biloba extract and an extraction method thereof, in particular to a raw material medicine for treating blood circulation disorder diseases such as cardiovascular and cerebrovascular diseases and peripheral blood vessels, and belongs to the technical field of traditional Chinese medicine preparation. Background technique [0002] Blood circulation disorders such as cardiovascular and cerebrovascular diseases and peripheral blood vessels are one of the most common clinical diseases and a major class of diseases that affect people's health and longevity. The role of Ginkgo biloba extract and its preparations in cardiovascular and cerebrovascular diseases and peripheral vascular diseases has attracted more and more attention from all over the world. Ginkgo biloba L. is an ancient relic plant, also known as ginkgo tree. Ginkgo biloba is a rare tree species in my country and a precious medicinal plant resource in the world....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K36/16A61K127/00A61P9/00
Inventor 庄洪波
Owner AOLING BODA MEDICINE SCI & TECH DEV BEIJING
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