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Medicine preparation for treating liver and gallbladder disease and its preparing process

A pharmaceutical preparation and technology for liver and gallbladder diseases, applied in the field of traditional Chinese medicine, can solve problems such as easy recurrence and achieve obvious therapeutic effects

Active Publication Date: 2007-08-15
HEHUANG PHARMA SHANGHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Surgery has certain limitations, and it is easy to relapse after surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1 prepares tablet of the present invention

[0017] In the GMP purification workshop, 1 part of rhubarb was crushed into fine powder, and passed through a 100-mesh sieve for later use; 6 parts of tangerine peel were placed in an extraction pot, and the volatile oil of tangerine peel was distilled and extracted. 15 parts of Polygonum cuspidatum, 6 parts of green bark, 9 parts of turmeric, 15 parts of hawthorn, and 9 parts of Imperata rhizome, respectively use 6 times the amount and 4 times the amount of 70% ethanol to reflux twice, each time for 1 hour, and concentrate the extract to a relative density of 1.10 ~ 1.20 (80 ~ 85 ℃ thermal measurement), vacuum drying (60 ~ 80 ℃) into a dry extract, the above rhubarb fine powder, tangerine peel volatile oil, dry extract powder plus 0.5 parts of microcrystalline cellulose, 0.5 parts of calcium sulfate , 0.5 parts of starch, and 0.5 parts of cetyl polyvinylpyrrolidone [PVP (k30)] are mixed and granulated, compressed ...

Embodiment 2

[0018] Embodiment 2 prepares tablet of the present invention

[0019] In the GMP purification workshop, 3 parts of rhubarb were crushed into fine powder, and passed through a 100-mesh sieve for later use; 18 parts of tangerine peel were placed in an extraction pot, and the volatile oil of tangerine peel was distilled and extracted. 45 parts of Polygonum cuspidatum, 18 parts of green bark, 27 parts of turmeric, 45 parts of hawthorn, and 27 parts of Imperata rhizome, respectively use 6 times the amount and 4 times the amount of 70% ethanol to reflux twice, each time for 1 hour, and the extract is concentrated to a relative density of 1.10 ~ 1.20 (80 ~ 85 ℃ thermal measurement), vacuum drying (60 ~ 80 ℃) into a dry extract, the above rhubarb fine powder, tangerine peel volatile oil, dry extract powder plus 0.5 parts of microcrystalline cellulose, 0.5 parts of calcium sulfate , 0.5 parts of starch, and 0.5 parts of cetyl polyvinylpyrrolidone [PVP (k30)] are mixed and granulated, c...

Embodiment 3

[0020] Embodiment 3 prepares tablet of the present invention

[0021] In the GMP purification workshop, 5 parts of rhubarb were crushed into fine powder, and passed through a 100-mesh sieve for later use; 30 parts of tangerine peel were placed in an extraction pot, and the volatile oil of tangerine peel was distilled and extracted. 75 parts of Polygonum cuspidatum, 30 parts of green bark, 45 parts of turmeric, 75 parts of hawthorn, and 45 parts of Imperata rhizome, respectively use 6 times the amount and 4 times the amount of 70% ethanol to reflux twice, each time for 1 hour, and the extract is concentrated to a relative density of 1.10 ~ 1.20 (80 ~ 85 ℃ thermal measurement), vacuum drying (60 ~ 80 ℃) into a dry extract, the above rhubarb fine powder, tangerine peel volatile oil, dry extract powder plus 0.5 parts of microcrystalline cellulose, 0.5 parts of calcium sulfate , 0.5 parts of starch, and 0.5 parts of cetyl polyvinylpyrrolidone [PVP (k30)] are mixed and granulated, c...

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PUM

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Abstract

The present invention belongs to the field of Chinese medicine technology, and is one kind of medicine preparation for treating hepatic and biliary diseases. The medicine is prepared with Chinese medicinal materials including rhubarb, giant knotwood, ash bark, dried orange peel, curcuma root, haw and cogongrass rhizome and medicinal supplementary material, and through crushing the Chinese medicine material into fine powder, extracting volatile oil, ethanol reflux, decompression concentration of the extracted liquid, vacuum drying to obtain extractum powder, adding supplementary material, mixing, pelletizing and other steps. The medicine is prepared into tablet, capsule or granule. Tests and clinical application show that the medicine has obvious curative effect and no obvious toxic side effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a pharmaceutical preparation for treating liver and gallbladder diseases, in particular to a preparation for treating liver and gallbladder diseases containing raw materials such as rhubarb rhubarb, polygonum cuspidatum, green peel, tangerine peel and the like and a preparation method thereof. Background technique [0002] Along with the general improvement of people's living standards, people have played a qualitative change in diet, so the incidence of liver and gallbladder disease also increases thereupon. According to incomplete statistics, liver and gallbladder disease accounts for about 18% of the total prevalence, and it is increasing year by year. It is one of the common and frequently-occurring diseases. Traditional Chinese medicine believes that the liver and gallbladder are the exterior and interior of each other, and liver and gallbladder diseases often affec...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K9/20A61K9/16A61K36/9066A61K36/899A61K36/752A61K36/734A61K36/708A61K36/704A61P1/16
Inventor 王成荣康爱仙朱培庭王富嘉张正光乐国祥
Owner HEHUANG PHARMA SHANGHAI
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