Chinese medicinal preparation for treating virus B hepatitis and preparation method thereof
A technology of viral hepatitis and traditional Chinese medicine preparations, which is applied in the direction of antiviral agents, medical formulas, and medical preparations containing active ingredients, etc., which can solve the problems of chemical ingredients that cause great harm to the human body, high cost of drug production, and large toxic and side effects. Enhance the immune function of the body, reduce the cost of treatment, and eliminate the effect of viruses
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[0053] The preparation method of the tablet of the present invention includes: taking 1500g of Hedyotis diffusa, 1500g of Oldenlandia diffusa, 1500g of Peran, 1500g of Gardenia, 1500g of Bupleurum, 1500g of Caulis, 1500g of Alisma orientalis, 1500g of Forsythia, 1500g of Radix isatidis, 1500g of Poria cocos, Prunella vulgaris 1500g, Schisandra 1500g, Fructus Aurantii 1500g, Atractylodes 1500g, Cornus 1500g, Ligustrum lucidum 1500g, White peony 1500g, Scutellaria 1500g, Turmeric 1500g, Perilla 1500g, Chuanzi 1500g, Zedoary 1500g, Gentiana 1500g, the The components are mixed according to the proportion, put into the pulverizer and pulverized into fine powder. After the fine powder is sieved, it is put into the acid and alkali-resistant dipping pot, and it is immersed with ethanol for 10-20 days at room temperature. Squeeze and filter, take the filtrate after separation, heat and concentrate to a paste and mix with starch, put it in an oven, control at 100°C, and press to make tabl...
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[0065] Experimental example 2: Long-term toxicity test data
[0066] The results of the long-term animal toxicity test of the capsules of the present invention after intragastric administration for 6 months: SD rats were divided into three groups, 30 in each group, half male and female (divided into three high, medium, and low dose groups, each with 10 Only), wherein the first group was given normal saline by gavage; the second group was given the present invention by gavage at 0.25g, 2.5g and 12.5g / kg.d; the third group was given lovastatin by gavage The doses are 0.5mg, 5.0mg and 50.0mg / kg.d. During the administration period, the clinical manifestations, hematology, blood biochemistry, organ coefficient and histopathology of each group of animals after administration were observed for drug toxicity evaluation. Research results: The main toxic reaction was manifested in the lovastatin 50mg / kg.d and 5.0mg groups. After the administration, the SD rats had salivation, fluffy hair,...
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[0135] Example 1: Jia Mou, male, 38 years old, the patient suffered from acute viral hepatitis (jaundice) 3 years ago, liver function was significantly impaired, due to a large amount of glucose infusion and then secondary diabetes, hospitalized for nearly two years, liver after discharge Function fluctuates from time to time. Liver function is obviously abnormal in the past one month. Check before visit: alanine aminotransferase 372U, musk turbid 18U, fasting blood sugar 190mg%, urine sugar (+++), dry mouth, bitter mouth, yellow urine, two Symptoms are swelling and painful, sometimes there is bleeding, tongue coating is yellow, the edges are red, and the pulse is thin. Taking the present invention, the prescription: 12g of Hedyotis diffusa, 11g of Hedyotis diffusa, 12g of Peilan, 13g of Gardenia, 12g of Bupleurum, 13g of Caulis, 12g of Alisma, Forsythia 14g, Isatis root 12g, Poria 11g, Prunella 12g , Schisandra 13g, Citrus aurantium 12g, Atractylodes macrocephala 12g, Cornus 1...
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