New type antibiotic peptide of peptaibol and preparing technique

A technology of piperomycin and trichoderma, applied in the field of new antibiotic peptide-piperomycin, can solve the problems of restricting in-depth research and application, high synthesis cost, and achieve the effect of not easy drug resistance and good inhibitory effect.
CN1332979CInactive Publication Date: 2007-08-22SHANDONG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANDONG UNIV
Publication Date
2007-08-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

A pipomycin as a novel antibiotic peptide is prepared from Trichoderma through solid and liquid fermenting in aseptic GMP environment, and two-step separation. Three pipomycins are prepared, which feature broad-spectrum bacterium suppressing activity, so it can be used to prevent and eliminate the diseases and pests of plant.
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Description

(1) Technical field

[0001] The invention relates to the separation and preparation of a novel antibiotic peptide-piperamycin from a fermentation product of Trichoderma, belonging to the field of biotechnology. (2) Background technology

[0002] Chemical pesticides have made important contributions to the prevention and control of diseases, insects, weeds and rodents. However, with the large-scale application of chemical pesticides, the problem of "3R" (that is, drug resistance, Resurgence, and pesticide residue Residuce) has become more and more serious, seriously affecting agricultural products. Food safety has become one of the main restrictive factors for my country's agricultural products to enter the international market. It is an inevitable trend that a large number of chemical pesticides with high toxicity, high residue and killing natural enemies will gradually be restricted in use until production is completely banned. According to the statistics of the Food and Agr...

Claims

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