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Beetoxin injection and its preparing process

A technology of injection and bee venom, applied in respiratory system diseases, skin diseases, bone diseases, etc., can solve the problems of preparing injections without scorpion venom and bee venom, and achieve the enhancement of human immunity, low dosage and low price. Effect

Inactive Publication Date: 2002-08-14
贾文杰 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the pharmacology and preparation research of scorpion venom has made some progress, there is no record of combining scorpion venom and bee venom to prepare injection in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0015] Select healthy bumblebees, stimulate them to discharge venom, dissolve in distilled water, centrifuge to remove dust, and filter through a microporous membrane to obtain bee venom aqueous solution, which is further freeze-dried to obtain bee venom dry powder. In a sterile room, at about 1-6 ° C, accurately weigh 10 mg of collected bee venom, dissolve and dilute an appropriate amount of sterile saline solution to 1000 ml, filter bacteria and pyrogens through a microporous membrane, and pack into ampoules (10 μg / ml) to obtain bee venom physiological saline injection, and store it at 4-5°C for later use.

preparation Embodiment 2

[0017] 1-6°C, under sterile operating conditions, accurately weigh 8 mg of commercially available bee venom (Sigma, USA), dissolve and dilute to 1000 ml with an appropriate amount of sterile saline solution, filter bacteria and pyrogens through a microporous membrane, and separate Put it in an ampoule (8 μg / ml) to get bee venom physiological saline injection, and store it at 4-5°C for later use.

preparation Embodiment 3

[0019] 1-6°C, under aseptic conditions, accurately weigh 12 mg of home-made Vespa venom, dissolve it with an appropriate amount of sterile saline solution and dilute to 1000 ml, filter through a microporous membrane to remove bacteria and pyrogens, and pack into ampoules (12 μg / ml) to obtain bee venom saline injection, and store it at 4-5°C for later use.

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PUM

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Abstract

A compound beetoxin injection for treating neuralgia, periomethritis, rheumatic and rheumatoid arthritis, allergic dermatopathy, allergic rhinitis, etc and its preparing process are disclosed. Its advantages include correct dosage, high curative effect and high safety.

Description

technical field [0001] The invention relates to a bee venom injection and a preparation method thereof, and also relates to a compound bee venom injection composed of bee venom and scorpion venom and a preparation method thereof. Background technique [0002] Apitherapy is an abbreviation for human health care with bees and bee products. Bee products include honey, bee pollen, beeswax, propolis, royal jelly, bee venom, bees and their larvae and pupae. Apitherapy in a narrow sense is a method of medical care with bee venom, which is divided into artificially extracted bee venom injection and live bee stinger injection, and the latter is divided into straight thorn and scattered thorn, that is, live bee stinger is directly inserted The human body and the bee needles that will be pulled out are continuously and quickly pierced and pulled out at different points on the human body. The history of human beings using bee venom to treat joint rheumatism can be ...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61P11/00A61P11/02A61P19/02A61P25/04A61P29/00A61P31/00A61P35/00A61P37/08
Inventor 贾文杰贾灵生
Owner 贾文杰
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