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Chinese medicine preparation for treating lithiasis of urinary system, and preparing method thereof

A technology of urinary stones and traditional Chinese medicine preparations, which is applied in the direction of urinary system diseases, medical formulas, medical preparations containing active ingredients, etc., to achieve the effect of short course of treatment, no toxic side effects, and inhibition of stone formation

Inactive Publication Date: 2003-05-28
JINSHAN NATURAL PLANT MEDICINE INST SHENZHEN CITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no single-flavored walnut kernel formulation on the market at home and abroad

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Preparation of soft capsules

[0021] Take 4Kg of walnut kernel medicinal material, separate walnut kernel oil by pressing method, 1.0Kg, add 15Kg of 70% ethanol to the dregs, reflux extraction for 1.5 hours, filter, add 10Kg of 70% ethanol to the dregs, reflux extraction for 1.5 hours, filter and combine Ethanol extract, recover ethanol under reduced pressure, concentrate to a relative density of 1.20 (50°C), add 95% ethanol to make the liquid alcohol content 70-80%, fully stir, let stand for 12 hours, filter, recover ethanol under reduced pressure, The concentrate was spray-dried to obtain 200 g of walnut kernel extract dry powder. Take 200g of walnut kernel extract dry powder, 285g of walnut kernel oil, and 15g of glycerin, mix them evenly, grind them in a colloid mill for 15 minutes, sieve them, put them in a soft capsule pressing machine, and press them into 1000 soft capsules, then pack them separately.

Embodiment 2

[0023] The clinical result of the soft capsule of embodiment 1

[0024] The soft capsule (0.5g / every grain) prepared by embodiment 1 is every day 3 times, once 3, is used for 60 examples of urinary calculi (wherein 45 examples of kidney stones, 15 examples of ureteral calculi), the result is cured (stones are excreted from the body) ) in 46 cases, 9 cases were effective (stones became smaller), and 5 cases were ineffective.

Embodiment 3

[0025] The preparation of embodiment 3 capsules

[0026] Take 4Kg of walnut kernel medicinal material, crush it into coarse powder, add 32Kg of water, decoct and extract for 2 hours, filter, add 24Kg of water to the dregs, decoct and extract for 2 hours, filter, combine the water extract, and pass the aqueous solution through the AB-8 resin column , Resin 2Kg, wash with 4L water first after finishing the liquid medicine, then elute with 4L 60% ethanol, collect 60% ethanol eluent, reclaim ethanol under reduced pressure, reclaim ethanol under reduced pressure, concentrate to relative density 1.10-1.30, ( 50°C), add 80g of starch and 120g of microcrystalline cellulose, stir evenly, make a suitable soft material, granulate with 16 meshes, dry under reduced pressure at 80°C until the water content is below 6%, to obtain dry granules, pack into capsules, pack, and obtain 1000 capsules.

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PUM

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Abstract

A Chinese medicine in any form (soft capsuel is preferable) for treating the calculosis in urinary system is prepared from walnut kernel.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating urinary stones and a preparation method thereof. The preparation is made of walnut kernels. Background technique: [0002] Urinary calculus is a common and frequently-occurring disease in clinical practice. The etiology is not very clear, but it is related to factors such as foreign bodies, obstruction, infection, nutritional disorders, endocrine and metabolic disorders, and long-term bed rest. Urinary stones can cause severe pain and hematuria, and long-term obstruction of stones can cause urinary tract water above the obstruction site and functional impairment. Treatment methods include surgery, extracorporeal shock wave lithotripsy, and drug therapy. There are many Chinese patent medicines for the treatment of urinary calculi on the market, but most of them have the disadvantages of large dosage, long stone ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P13/04
Inventor 施建勇
Owner JINSHAN NATURAL PLANT MEDICINE INST SHENZHEN CITY
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