Tissue engineering compound material for repairing nerve injury and its preparation

A nerve injury and repair material technology, applied in medical science, surgery, etc., can solve the problems of unfavorable regenerative fiber directional growth, irregularity, and effect, etc., to improve mechanical properties, reduce decomposition speed, increase tensile strength and The effect of stiffness
CN1546182AInactive Publication Date: 2004-11-17FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FOURTH MILITARY MEDICAL UNIVERSITY
Publication Date
2004-11-17
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a complex type tissue engineering nerve damage renovation material, which comprises type I collagen, heparitin sulfate, type IV collagen and gelatin. The material has simple adjusting inner diameter and uniform single orientation axial bore, it is easy to be made into different external forms, e.g. cylinder or rectangle.
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Description

technical field

[0001] The present invention aims to develop a bridge for repairing central and peripheral nerve injuries with good biocompatibility and biodegradability, involving various biological raw materials such as collagen, gelatin and aminoglycans, as well as their processing technology and production method . The material can be used not only for basic research on nerve injury repair, but also for clinical bridging repair after segmental injury and defect of human spinal cord and peripheral nerve. Background technique

[0002] The extracellular matrix (ECM) is the basis for cells to survive and maintain cell functions and biological characteristics. It is the basic carrier of life and provides organisms with scaffolds for maintaining structures and places for biological functions. The functions of ECM, such as cell adhesion, intercellular signal transmission, and migration, are unique and unavailable to other substances, and have a profound impact on the functions...

Claims

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