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Chitosan chewing tablet and its preparation method

A technology for chitosan oligosaccharides and chewable tablets, applied in the field of new chewable tablets and their production, can solve the problems of products without any taste and fragrance, affecting the functional effects of functional ingredients, and trouble for consumers to take them, so as to improve color and luster, prevent Moisture absorption, delicate and refreshing effect

Inactive Publication Date: 2005-01-26
WUHAN HAOTIAN BIOTECH IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as a food raw material, chitosan has a certain astringent taste, which affects the production of products. Therefore, the existing health food with chitosan as the main functional component on the market is mainly in the form of capsules (such as Nanjing Zhongke Biochemical Technology Co., Ltd. The company's Zhongke Jiaer Capsules; Beijing Weimeihengda Health Products Technology Co., Ltd.'s Weikexin Slimming Capsules; Dalian Tianwei Pharmaceutical Co., Ltd.'s Paiqi Arrangement Lead Capsules, etc.)
Although the form of capsules can embed the astringent taste of chitosan, it needs to be swallowed with warm water when taking it, which brings certain troubles to consumers; the product has no taste and fragrance, which makes people feel like taking medicine; at the same time, capsules It needs to be disintegrated in the stomach before it can be absorbed, which affects the exertion of the functional effect of the functional ingredients

Method used

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  • Chitosan chewing tablet and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Example 1: Chitooligosaccharide Chewable Tablets with Milk Flavor and High Sweetness

[0048] Accurately weigh 20kg of chitooligosaccharides, 25kg of pregelatinized modified starch, 15kg of maltodextrin, 15kg of glucose, 1kg of 1% beta-carotenoids, 50g of vanilla powder essence and 50g of cream powder essence, and mix each Mix the ingredients evenly. Prepare 12L of 30% ethanol solution, and dissolve 23.5kg of sucrose in the ethanol solution. Moisten the mixed ingredients with the prepared sucrose solution to make a soft material, and send it to the granulator for granulation. The obtained wet granules are dried with a drier at 50° C. until the moisture is lower than 3%, and then 100 g of magnesium stearate is evenly added. In order to prevent moisture absorption, the dry granules are quickly fed into the tablet machine for compression. Each chewable tablet has a net weight of 1.5g. The finished product of the chitooligosaccharide chewable tablet of the present inven...

Embodiment 2

[0049]Example 2: Fruity and low-sweet chitooligosaccharide chewable tablets

[0050] Accurately weigh 22kg of chitooligosaccharides, 20kg of pregelatinized modified starch, 20kg of maltodextrin, 10kg of glucose, 1kg of 1% beta-carotenoids, 50g of pineapple powder essence and 50g of orange powder essence, and mix each Mix the ingredients evenly. Prepare 12L of 30% ethanol solution, and dissolve 20.5kg of sucrose in the ethanol solution. Moisten the mixed ingredients with the prepared sucrose solution to make a soft material, and send it to the granulator for granulation. The obtained wet granules were dried with a drier at 50° C. until the moisture was lower than 3%, and then 150 g of magnesium stearate was evenly added. In order to prevent moisture absorption, the dry granules are quickly fed into the tablet machine for compression. Each chewable tablet has a net weight of 1.5g. The chitooligosaccharide chewable tablet of the present invention is the finished product that ...

Embodiment 3

[0051] Example 3 Determination of Hypolipidemic Activity of Chitooligosaccharide Chewable Tablets

[0052] 1. Determination of the effect of chitooligosaccharide chewable tablets on blood lipid regulation

[0053] Five treatments were set up, namely high, medium and low dose groups, a basic control group and a high-fat control group. Male Wistar rats with a body weight of 150-210 g were fed for 1 week, blood was collected to measure serum triglyceride index, and the animals were randomly divided into 5 groups according to the measurement results, with 8 test rats in each group. Each dose group was fed with the aqueous solution of chitooligosaccharide chewable tablets produced by Example 1 once a day, continuously for 28 days, fed a high-fat feed while giving the test substance, free to eat and drink, weighed once every 4 days, and Adjust the amount of chitooligosaccharide chewable tablet solution for gavage according to the body weight. Both the high-fat control group and th...

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Abstract

Disclosed is chitosan chewing tablet and its preparation method, wherein the tablet comprises chitosan and pre-gelatinated modified starch, whose weight proportion is 10-30 parts and 20-40 parts.

Description

technical field [0001] The invention belongs to the technical field of food engineering, and in particular relates to a novel chewable tablet and a production method thereof. Background technique [0002] Since the discovery of chitin by the French scholar Braqueno in 1811, its research and development have been highly valued by the scientific community all over the world for more than 100 years. The Japanese government invests more than 5 billion yuan in scientific research and development every year, and there is a patent declaration for chitosan application every three days on average. In 1997, the research and development subject of chitosan was included in the Ninth Five-Year Plan of the National Science and Technology Commission, and later included in the National 863 Key Research Plan. [0003] The product of deacetylation of chitin is called chitosan, which is the only cationic edible fiber found in nature so far. As a class of renewable a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/722A61P37/02A61P43/00
Inventor 黄文雷朝亮王益周兴苗程祥国冯国安
Owner WUHAN HAOTIAN BIOTECH IND
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