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Anthemonhagic medicament for quick blood coagulation and diminish inflammation

An anti-inflammatory and hemostatic drug technology, applied in the field of quick-setting anti-inflammatory and hemostatic drugs, can solve the problems of not being able to prevent wound inflammation and poor hemostatic effect, and achieve the promotion of tissue absorption and healing, strong anti-killing effect, and good biocompatibility Effect

Active Publication Date: 2005-08-31
GUANGDONG SHUNFENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, there have been many studies on hemostatic materials, among which the most sold in the market is "hemostatic patch". Among the many "hemostatic patches", many of them only contain anti-inflammatory ingredients and do not contain hemostatic ingredients, so their hemostatic effect is poor. Used for small wounds; some contain hemostatic ingredients (such as Chinese herbal medicine hemostatic ingredients) but do not contain anti-inflammatory ingredients. Although they have hemostatic effect, they cannot prevent wound inflammation well

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0014] Taking the hemostatic patch as an example, its formula (weight ratio) is as follows:

[0015] Chlorhexidine 0.5~2%

[0016] Chitosan 5~25%

[0017] Panax notoginseng 20~35%

[0018] Purple Pearl 20~35%

[0019] Polyurethane substrate 18~25%

[0020] Preparation method:

[0021] (1) Chinese herbal medicine Panax notoginseng and purple pearl are crushed into coarse powder, soaked in 65% ethanol for 2 hours, extracted in an ultrasonic extractor with ultrasonic waves at 60°C for 45 minutes, extracted twice in this way, combined extracts, concentrated and recovered ethanol, The concentrated solution is added with water and precipitated overnight, filtered to remove impurities such as resins and gums, and concentrated into a liquid extract.

[0022] (2) Under clean conditions, dissolve chlorhexidine and chitosan in acetic acid solution, add polyurethane base material and Chinese herbal medicine liquid extract extracted from item (1), stir and mix to form a gel, and evenl...

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PUM

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Abstract

An inflammation-relieving staltic medicine for first aid and surgical operation is proportionally prepared from chlorhexidine, chitosan, notoginseng, beauty berry and polyurethane as matrix.

Description

(1) Technical field [0001] The invention relates to an absorbable anti-inflammatory and hemostatic material used on the tissue surface after trauma and surgery, in particular to a quick-setting anti-inflammatory and hemostatic agent. (2) Background technology [0002] Hemostatic materials play an important role in bleeding from trauma, battlefields, traffic accidents and surgical wounds. In recent years, there have been many studies on hemostatic materials, among which the most sold in the market is "hemostatic patch". Among the many "hemostatic patches", many of them only contain anti-inflammatory ingredients and do not contain hemostatic ingredients, so their hemostatic effect is poor. It is used for small wounds; some contain hemostatic ingredients (such as Chinese herbal medicine hemostatic ingredients) but do not contain anti-inflammatory ingredients. Although they have hemostatic effect, they cannot prevent wound inflammation well. (3) Contents of the invention [0...

Claims

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Application Information

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IPC IPC(8): A61K9/14A61K9/70A61L15/44A61P7/04A61P17/00
Inventor 刘贤英林文红
Owner GUANGDONG SHUNFENG PHARMA
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