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Babu agent of Chinese traditional medicine for treating asthma and preparation method

A technology of cataplasm and traditional Chinese medicine, applied in the field of traditional Chinese medicine cataplasm for treating asthma and its preparation, which can solve the problems of difficult control of drug dose, inconvenient use, and difficult productization

Inactive Publication Date: 2005-08-31
SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The white mustard seed coating prescription in "Zhang's Yitong" is a classic prescription for treating asthma, and its clinical effect is excellent. However, in clinical practice, the medicines in the prescription are usually ground into fine powder, then made into a paste with ginger juice, and applied to the corresponding acupuncture points. , inconvenient to use, difficult to productize, and difficult to control the dosage

Method used

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Examples

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Effect test

preparation example Construction

[0017] 2. Preparation of cataplasm blank matrix

[0018] 2.1 Prescription (weight ratio) of cataplasm blank matrix

[0019] 5-10 parts of gelatin

[0020] Sodium polyacrylate 1~5 parts

[0021] Sodium carboxymethyl cellulose 0.5~5 parts

[0022] 3-10 parts of polyvinyl alcohol

[0023] Gum Arabic 1~8 parts

[0024] 10-30 parts of glycerin

[0025] Ethylparaben 0.05~0.25 parts

[0026] Azone 0.5~2.5 parts

[0027] Appropriate amount of water

[0028] 2.2 Preparation process of cataplasm blank matrix

[0029] Phase A: Moisten sodium polyacrylate with glycerin, then add gelatin and ethylparaben, mix well, add an appropriate amount of water, and dissolve into a gel at 50-90°C;

[0030] Phase B: Dissolve polyvinyl alcohol in water at 70-110°C to form a thin gel;

[0031] Phase C: mix sodium carboxymethyl cellulose and gum arabic, moisten it with glycerin, and dissolve it into a thin gel at 50-90°C;

[0032] Mix phase B and phase C, then add phase A, and add azone and mix...

Embodiment 1

[0038] 1. Weigh a total of 5.185 kg of medicinal materials according to the ratio of Rhizoma Rhizoma: Asarum: White Mustard Seed: Kansui = 30: 30: 30: 1.5, and extract each extract according to the following process: A, Rhizoma Rhizoma powder use 1.5 times the amount of 14 Wet with % ammonia water, then reflux twice with 5 times of 95% ethanol for 2 hours each time, combine the ethanol extracts, concentrate under reduced pressure (45 degrees) to obtain an extract, and the yield of the extract is 1.46%. B. Asarum powder was ultrasonically extracted 2 times with 4 to 5 times of ether, each time for 15 minutes, the ether extracts were combined, and concentrated at 40 degrees under normal pressure to obtain an extract containing volatile oil. The yield of volatile oil extract was 1.26%. The dregs are extracted twice with 4 to 5 times the amount of 95% ethanol under reflux, each time for 2 hours, the ethanol extracts are combined, and concentrated under reduced pressure below 45 deg...

Embodiment 2

[0053] 1. Weigh a total of 5.185 kg of medicinal materials according to the ratio of Rhizoma Rhizoma: Asarum: White Mustard Seed: Kansui=30: 15: 15: 0.75, and extract each extract according to the following process: A, Rhizoma Rhizoma powder use 2.25 times the amount of 14 % ammonia water, and then refluxed with 7 times of ethanol for 3 times, each time for 2 hours, combined the ethanol extracts, concentrated under reduced pressure to obtain an extract, and the yield of the extract was 2%. B. Asarum powder was ultrasonically extracted 3 times with 3 times ether, each time for 20 minutes, the ether extracts were combined, concentrated at 35°C under normal pressure to obtain an extract containing volatile oil, and the yield of volatile oil extract was 1.4%. The dregs were extracted twice with 5 times the amount of ethanol under reflux, each time for 2 hours, the ethanol extracts were combined, and concentrated under reduced pressure at 35°C to obtain an extract containing asarone...

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PUM

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Abstract

A Chinese medicine for treating asthma is prepared from corydalis tuber, asarum herb, Kan-sui root, white mustard seed and percutaneous osmosis promoter.

Description

[technical field] [0001] The invention relates to a medicine for treating asthma and a preparation method thereof, in particular to a traditional Chinese medicine cataplasm for treating asthma and a preparation method thereof. [Background technique] [0002] The white mustard seed coating prescription in "Zhang's Yitong" is a classic prescription for treating asthma, and its clinical effect is excellent. However, in clinical practice, the medicines in the prescription are usually ground into fine powder, then made into a paste with ginger juice, and applied to the corresponding acupoints , inconvenient to use, difficult to productize, and difficult to control the dosage. [Content of the invention] [0003] In the present invention, the white mustard seed coating prescription Zhongyuanhu, Asarum, Gansui, and white mustard seed in "Zhang's Yitong" are prepared into an extract by modern extraction and separation technology, and a transdermal penetration enhancer is added, and...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61P11/06
Inventor 徐月红王茵萍王冬梅陈宝胡海燕
Owner SUN YAT SEN UNIV
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