Jaundice capillaris drip pill and its preparation method

A technology of jaundice and sputum, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of unfavorable improvement of patients' ability to seek medical treatment, low dissolution rate, and low drug content, and achieves improved bioavailability. effect of rapid dissolution and absorption, high bioavailability

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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  • Summary
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
Granules also have defects such as low drug content, inaccurate measurement, and inconvenient taking.
In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033] Several specific examples are now used to further illustrate the preparation method of the Jaundice Yinchen dripping pill of the present invention.

[0034] The first group: single matrix test

[0035] 1. Raw materials: According to [Appendix], a dry powder containing four active ingredients of traditional Chinese medicine, including Yinchen, Scutellaria, Rhubarb, and Licorice, is prepared in advance for use;

[0036] 2. Matrix: polyethylene glycol (1000~20000) , Polyoxy 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. Medicinal carrier

[0037] 3. Proportion: in g or kg, in parts by weight, drug extract: matrix = 1:1 to 1:9;

[0038] 4. Then prepare according to the process of [Preparation Method] 4-7, that is, various specifications of Jaundice Yinchen dripping pills can be prepared.

[0039] [test results]

[0040] Test 1: In order to observe the difference in qua...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating infectious icterohepatitis is prepared from oriental wormwood, scutallaria root, rhubarb, liquorice root and medicinal carrier. Its preparing process is also disclosed.

Description

Technical field [0001] The invention relates to a medicinal composition for treating acute and chronic jaundice-type infectious hepatitis, as well as diseases such as liver and gallbladder damp-heat syndrome, which has the effects of clearing away heat, promoting choleretics, and reducing jaundice, and particularly relates to a pharmaceutical composition containing Yinchen, scutellaria, rhubarb, and licorice An oral preparation of a pharmaceutical composition prepared by using the active pharmaceutical ingredient extracts of four traditional Chinese medicines as raw materials. Background technique [0002] Jaundice Yinchen granules prepared according to the formula and extraction process given in the national drug standard WS-10442(ZD-0442)-2002 are a kind of heat-clearing and choleretic, anti-jaundice effect, used for acute and chronic jaundice Infectious hepatitis, as well as granular preparations for the treatment of diseases such as liver and gallbladder damp-heat syndrome, h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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