Tongkening drip pill used for assistant treating of tumour and its preparation method

A technology of adjuvant therapy, Ning dripping pills, applied in the direction of antitumor drugs, medical preparations containing active ingredients, pill delivery, etc. Gastrointestinal irritation symptoms, improved bioavailability, dissolution and absorption acceleration

Inactive Publication Date: 2005-10-26
JIANGSU QINGJIANG PHARMA
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  • Summary
  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the limitations of existing injection preparation technology and the influence of the complexity of traditional Chinese medicine ingredients, traditional Chinese medicine injections are often prone to acute allergic reactions or adverse reactions. At the same time, there are also difficulties in operation, great pain for patients, high manufacturing and medical costs, and inconvenient transportation and storage. , heavy economic burden for patients, unsuitable for family use and other disadvantages
[0008] In addition, due to preparation technology and other reasons, most oral preparations of drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability af

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of Tongkening dripping pills of the present invention will be further described.

[0032] [Group 1: Trials with a single substrate]

[0033] 1. Raw materials: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredients of traditional Chinese medicine horsetail and selaginella is prepared in advance for later use;

[0034] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0036] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Tongkening Dropping Pills of different specifications.

[0037] [test results]

[0038]Test 1: In order to observe th...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for the auxiliary therapy to cancer pain is prepared from scouring rush herb, tamariskoid spikemoss herb, and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has the functions of clearing away heat and detoxifying, dispelling stagnation and dredging collaterals, and is used for adjuvant treatment of malignant tumor pain. A pharmaceutical composition orally prepared. Background technique [0002] According to the formula and extraction process given in the national drug standard WS-10838 (ZD-0838)-2002, Tongkening Injection is a traditional Chinese medicine injection used for the adjuvant treatment of malignant tumor pain. Clinically verified, with stable quality and definite curative effect, it is a common drug used clinically and at home to treat the above diseases. [0003] The following is the formula and extraction process given in the pharmaceutical standard WS-10838 (ZD-0838)-2002: [0004] Prescription: Horsetail 2000g, Selaginella 2000g; [0005] Preparation method: decoct the above two medicinal materials with water twice, the first tim...

Claims

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Application Information

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Inventor 曲韵智
Owner JIANGSU QINGJIANG PHARMA
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