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Earthworm drip pill and its preparation method

A technology of Dilong dripping pills and Dilong, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as low dissolution rate, unfavorable improvement of patients' ability to seek medical treatment, and influence on treatment effects, etc., to achieve Accelerated dissolution and absorption, improved bioavailability, less allergic reactions

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0008] In addition, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the quality of the drug. Efficacy also directly affects the therapeutic effect
At the same time, conventional oral dosage forms often produce relatively large dust pollution during the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment.
The production process of conventional oral preparations is also relatively complicated, and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society

Method used

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Examples

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Embodiment Construction

[0032] Now with several groups of specific examples, the preparation method of Dilong dripping pills of the present invention will be further described.

[0033] Group 1: Tests with a single matrix

[0034] 1. Preparation of medicinal extract: according to [Preparation Method 1], the dry powder of the extract containing the active pharmaceutical ingredient of Dilong is prepared in advance for subsequent use;

[0035] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, Tween 80, polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate , glycerin gelatin, shellac;

[0036] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0037] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Dilong Dilong Pills of different specifications....

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating cough and asthma is prepared from earthworm and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has antiasthma and antitussive effects and is used for the treatment of cough, wheezing and other diseases caused by bronchial asthma, in particular to an oral preparation of the pharmaceutical composition prepared from the traditional Chinese medicine Guangdilong. Background technique [0002] Dilong Injection, prepared according to the preparation method given in the National Drug Standard WS-11340 (ZD-1340)-2002, is an anti-asthma and cough-relieving effect, and is used for coughing, wheezing and other diseases caused by bronchial asthma. The pure Chinese medicine injection for treatment has been clinically verified and has definite curative effect. It is a commonly used drug for clinical and family treatment of the above diseases. [0003] The following is the formula, process and brief description given in the pharmaceutical standard WS-11340 (ZD-1340)-2002: [0004] Prescription: Guangd...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/62
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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