Compound preparation of baikal skullcap root

A technology of compound Scutellaria baicalensis and preparations, which is applied in the directions of anti-inflammatory agents, pill delivery, pharmaceutical formulations, etc., can solve the problems of unsatisfactory chemical drug treatment and the like

Active Publication Date: 2005-11-23
肇庆星湖制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Various chemical drugs are not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Embodiment 1: compound scutellaria baicalensis dispersible tablet

[0081] Scutellaria baicalensis 800g, Polygonum cuspidatum 800g,

[0082] Andrographis paniculata 800g, ten major contributions 800g

[0083] Filler: Lactose 52.5g

[0084] 95g pre-caramelized starch

[0085] Mannitol 17.5g

[0086] Disintegrant: cross-linked polyvinylpyrrolidone 21g

[0087] Sodium carboxymethyl starch 21g

[0088] Lubricant: micronized silica gel 5g;

[0089] Binder: 8% polyvinylpyrrolidone solution in 85% ethanol

[0090] Makes 1000 pieces

[0091] Take Scutellaria baicalensis and add water to decoct twice, the first time is 2 hours, the second time is 1 hour, combine the decoction, filter, the filtrate is concentrated to an appropriate amount, and dry to obtain a dry extract, which is set aside. Boil twice, 1 hour each time, combine the decoction, filter, concentrate the filtrate to an appropriate amount, dry, add the dry extract of Scutellaria baicale...

Embodiment 2

[0092] Embodiment 2: compound scutellaria baicalensis dispersible tablet

[0093] Scutellaria baicalensis 1500g, Polygonum cuspidatum 1500g,

[0094] Andrographis paniculata 1500g, ten major contributions 1500g

[0095] Filler: Lactose 150g

[0096] 120g pre-caramelized starch

[0097] Mannitol 150g

[0098] Disintegrant: cross-linked polyvinylpyrrolidone 25g

[0099] Sodium carboxymethyl starch 25g

[0100] Lubricant: micronized silica gel 12g;

[0101] Binder: 8% polyvinylpyrrolidone solution in 85% ethanol

[0102] Makes 1000 pieces

[0103] Take Scutellaria baicalensis and add water to decoct twice, the first time is 2 hours, the second time is 1 hour, combine the decoction, filter, the filtrate is concentrated to an appropriate amount, dry, and dry extract is obtained, set aside. Boil twice, 2 hours each time, combine the decoction, filter, concentrate the filtrate to an appropriate amount, dry, add the dry extract of Scutellaria baicalensi...

Embodiment 3

[0104] Embodiment 3: compound scutellaria baicalensis dispersible tablet

[0105] Scutellaria baicalensis 400g, Polygonum cuspidatum 400g,

[0106] Andrographis paniculata 400g, ten major contributions 400g

[0107] Filler: Lactose 20g

[0108] 30g pre-caramelized starch

[0109] Mannitol 10g

[0110] Hydroxypropyl Beta Cyclodextrin 20g

[0111] Disintegrant: cross-linked polyvinylpyrrolidone 4g

[0112] Sodium carboxymethyl starch 1g

[0113] Lubricant: micronized silica gel 0.5g;

[0114] Binder: 8% polyvinylpyrrolidone solution in 85% ethanol

[0115] Makes 1000 pieces

[0116] Take Scutellaria baicalensis and add water to decoct twice, the first time is 2 hours, the second time is 1 hour, the decoction is combined, filtered, the filtrate is concentrated to an appropriate amount, hydroxypropyl beta cyclodextrin is added, spray-dried, and the dried scutellaria baicalensis extract is obtained. Extraction, set aside, Polygonum cuspidatum,...

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Abstract

Disclosed is a compound preparation of baikal skullcap root for treating throat pains, which is prepared from baikal skullcap root, giant knotweed rhizome, creat and Chinese mahonia. The preparation employs a sectionalized extraction method, which takes the mutual actions between the main pharmaceutical ingredients into consideration. The preparation has the advantages of high scutellaria root glycosides content, quick dissolving rate, and high biological availability, it can be used for treating herpes zoster.

Description

Technical field: [0001] The invention relates to the field of traditional Chinese medicines, in particular to a Scutellaria baicalensis preparation for sore throat and a preparation method. Background of the invention: [0002] Compound Huangqin Tablets are composed of Scutellaria baicalensis, Polygonum cuspidatum, Andrographis paniculata, and top ten merits. The dosage form of compound Huangqin sugar-coated tablets is recorded in the 18 volumes of traditional Chinese medicine preparations. It has the functions of clearing away heat and detoxification, cooling blood and reducing swelling. It is used for sore throat, aphtha of the mouth and tongue, cold and fever, damp-heat diarrhea in the large intestine, astringent pain due to hot stranguria, carbuncle and sore. The current standard of Compound Huangqin Tablets does not specify its composition and preparation method, and there is no content control item, which is not conducive to controlling the quality of Compound Huangqin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 叶耀良廖志钟
Owner 肇庆星湖制药有限公司
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