Gas-phase production of N-hydroxyethyl-pyrrolidone

Abstract

Gas-phase production of N-hydroxyethyl pyrrolidone is carried out by immersing and modifying Y-shaped molecular sieve from metal nitrate to obtain Y-shaped molecular sieve made from different metal cation, using modified Y-shaped molecular sieve as catalyst, reacting gamma-butyrolactone with cholamine at 240í½300íÒC, gas phase and normal pressure, and synthesizing intermediate N-hydroxyethyl pyrrolidone of N-vinyl pyrrolidone. Its advantages include simple process, higher recovery rate and less separation and purification steps.

Description

technical field [0001] The invention relates to a gas-phase preparation method of N-hydroxyethylpyrrolidone (NHP). Background technique [0002] Polyvinylpyrrolidone (PVP) is a very important water-soluble polymer fine chemical, which is polymerized from monomer N-vinylpyrrolidone (NVP). PVP polymer has excellent properties such as excellent solubility, physiological compatibility (low toxicity), chemical stability, film formation, solubilization, adhesive ability, water absorption and moisture retention, etc., making PVP widely used in biomedicine, medical and health The key to the preparation and application of PVP is the preparation of monomer NVP. [0003] The acetylene method is the earliest and most mature NVP preparation method. It was first developed by W.Reppe, an acetylene chemist from BASF in Germany in the 1930s. Aldehyde addition synthesis of 1,4-butynediol, catalytic hydrogenation of 1,4-butynediol to synthesize 1,4-butanediol, catalytic dehydrogenation of 1,...

AI Technical Summary

Problems solved by technology

For a long time, the dehydration catalyst has become the research focus of this method. In fact, when using the liquid phase reaction between γ-butyrolactone and ethanolamine, from the perspective of industrial practice, although the single-pass yield is acceptable, there are long reaction times, High energy consumption and prolonged heating will affect the quality of the final product (such as darker color, odor, etc.), thus limiting the scope of application of the product

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