Preparation and application of propolis dripping pill

A technology for propolis and pharmaceutical preparations, which is applied to medical preparations containing active ingredients, pill delivery, digestive system, etc., can solve problems such as low bioavailability, slow disintegration and absorption, and achieve high bioavailability and fast onset of action. , the effect of relieving lesions

Inactive Publication Date: 2006-11-08
张益勤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This dosage form has the limitations of slow disintegration and absorption and low bioavailability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0017] The preparation process of the extract: take 200g of propolis, grind it finely, heat and reflux with ethanol to extract twice, the first time for 2 hours, the second time for 1 hour, filter, combine the filtrate, centrifuge, take the centrifugate to recover ethanol, and concentrate to Thick paste ready for use.

[0018] Implementation Example 1

[0019] Take 180g of propolis, grind it finely, heat and reflux with ethanol to extract twice, the first time for 2 hours, the second time for 1 hour, filter, combine the filtrate, centrifuge, take the centrifugate to recover ethanol, and concentrate to a thick paste. Take 100g of the above extract or pure propolis, add 700g of PEG5000 to mix and melt, put it on the dropping pill machine, and control the temperature of the dripper of the dropping pill machine at 70°C, use liquid paraffin as the condensing agent, and keep it warm at -5~5°C, Dropping, remove the condensate on the surface of the dropping pills.

[0020] Implement...

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PUM

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Abstract

The present invention provides a kind of propolis dripping pill and its preparation process. The propolis dripping pill is prepared with propolis extract or pure propolis added with proper matrix. The medicine has simple production process and is suitable for industrial production. It has high bioavailability and fast acting, and is suitable for use in treating hyperlipemia, stomatocace after radiotherapy and chemotherapy of tumor and other diseases.

Description

Technical field: [0001] The invention relates to a medicine for hyperlipidemia and oral ulcer after tumor radiotherapy and chemotherapy and a preparation method thereof, belonging to the technical field of medicine and preparation method thereof. Background technique: [0002] Propolis (proplis) is a resinous solid substance that honeybees collect from plant tooth buds or tree trunks and mix it with bee jaw glands and beeswax. It is one of the natural products produced by bees. Propolis was known in ancient Egypt as early as 3,000 years ago, and the role of propolis did not attract people's attention until after the 20th century. In the past 30 years, scholars at home and abroad have conducted systematic research on propolis, and extracted more than 150 compounds, which have a wide range of biological and pharmacological effects, including anti-bacterial, anti-viral, anti-fungal, anti-tumor, Anti-oxidation, anti-radiation, anti-inflammatory, pain relief, promotion of tissue...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K35/644A61P1/02A61P3/06
Inventor 张益勤
Owner 张益勤
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