104 results about "Post-chemotherapy" patented technology

The present invention provides propofol prodrugs, methods of making propofol prodrugs, pharmaceutical compositions of propofol prodrugs and methods of using propofol prodrugs and pharmaceutical compositions thereof to treat or prevent diseases or disorders such as migraine headache pain and post-chemotherapy or post-operative surgery nausea and vomiting.

The present invention provides propofol prodrugs, methods of making propofol prodrugs, pharmaceutical compositions of propofol prodrugs and methods of using propofol prodrugs and pharmaceutical compositions thereof to treat or prevent diseases or disorders such as migraine headache pain and post-chemotherapy or post-operative surgery nausea and vomiting.

The present invention provides propofol prodrugs, methods of making propofol prodrugs, pharmaceutical compositions of propofol prodrugs and methods of using propofol prodrugs and pharmaceutical compositions thereof to treat or prevent diseases or disorders such as migraine headache pain and post-chemotherapy or post-operative surgery nausea and vomiting.

A method for assisting an anti-cancer drug comprising administrating an effective amount of Antrodia camphorata fermentation solution to improve life quality of patient suffering from cancers after chemotherapy is provided.

A γ-butyrolactone compound as shown in Formula (I) and pharmaceutical composition thereof: wherein X═N, O, S, Se; and A and B are selected from substituents having the following formula: wherein R1, R2, R3, R4, and R5 are selected from a hydrogen atom, a halogen atom, a hydroxyl group, a mercapto group, an amino group, an alkoxy group, and a nitro group. The γ-butyrolactone compound and pharmaceutical composition thereof butyrolactone have inhibitory effects on hepatoma, ovarian cancer, breast cancer, lung cancer, malignant glioblastoma or colorectal carcinoma, and are cytotoxic with high specificity to inhibit Paclitaxel-resistant tumour cells at later stage of chemotherapy without any damage on normal cells.

The present invention provides a kind of propolis dripping pill and its preparation process. The propolis dripping pill is prepared with propolis extract or pure propolis added with proper matrix. The medicine has simple production process and is suitable for industrial production. It has high bioavailability and fast acting, and is suitable for use in treating hyperlipemia, stomatocace after radiotherapy and chemotherapy of tumor and other diseases.

A method for predicting sensitivity of a cervical cancer patient subjected to paclitaxel and cis-platinum adopted chemotherapy comprises the steps: S1, preopreative examination is performed; S2, nidus analysis is performed; S3, mathematical statistics is performed; S4 sensitivity judgment is performed, namely serum SCC-Ag level analysis and post-chemotherapy MRI measurement are performed to judge chemotherapy sensitivity so as to determine whether a drug resistance rule is subjected to a postoperative pathological measurement result or not, it is confirmed that the patient is drug-sensitive if the drug resistance rule is subjected to the postoperative pathological measurement result, and it is confirmed that the patient is drug-resistant if the drug resistance rule is not subjected to the postoperative pathological measurement result. An experimental result of drug resistance analysis performed by means of the method for predicting the sensitivity of the cervical cancer patient subjected to the paclitaxel and cis-platinum adopted chemotherapy shows that change of the serum SCC-Ag level has close relationship with the sensitivity of cervical squamous cell neoadjuvant chemotherapy, important information can be provided for judgment on drug resistance of the patient, SCC-Ag and magnetic resonance imaging can be jointly and clinically utilized to assess the chemotherapy sensitivity, and the prediction accuracy is obviously higher than the prediction accuracy of an MRI imageology method widely and clinically used at present.

The invention relates to a method for preparing nanometer stewed corrected injection, and relative application. Wherein, it prepares the total extractive of stewed mutton with ginseng and astragalus and astragalus root, with some findings, into nanometer carriers, to be made into water injection, frozen dried, etc. The inventive product has significant target function, better solution, and stable property. And it has low excitation. The invention can reduce the ache of cancer patient. And it can improve immunity, etc.

The invention relates to a cell growth and / or differentiation regulatory peptide comprising a sequence of about 9 to about 150 amino acids derived from acetylcholinesterase amino acid sequence, preferably from the C-terminal region of acetylcholinesterase. The invention also relates to pharmaceutical compositions comprising the peptides, particularly for use in promoting survival of stem cells, promoting differentiation of stem cells, promoting growth of stem cells and / or promoting the growth-enhancing effect of a growth factor on stem cells, alone, or in combination with other growth factors. Of particular interest is the use of the peptides in the treatment of thrombocytopenia, post-irradiation conditions, post-chemotherapy conditions, or conditions following massive blood loss and promotion of neural progenitors in use for cell therapies aimed at restoring neural functions in diseased individuals. Further, the invention relates to antibodies against the peptides, inter alia for diagnostic use, for example, the diagnosis of stress-induced male infertility. The invention also relates to in vitro and in vivo methods for screening of drugs that affect the central nervous system, and are potential modulators of interactions between the “readthrough” form of acetylcholinesterase, AChE-R, the intracellular receptor RACK1 and the kinase PKC.

Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.

The present invention is medicine for treating thrombocytopenia and anemia and its preparation process and quality control method, and belongs to the field of Chinese medicine technology. The medicine is prepared with donkey-hide gelatin 3.5-6.5 weight portions, astragalus root 140-260 weight portions, angelica 105-195 weight portions, date 70-130 weight portions and antler gelatin 10.5-19.5 weight portions. It has the functions of invigorating qi, nourishing blood, and benefiting kidney and spleen, and is used in treating thrombocytopenia and anemia. It has also certain curative effect on leucopenia caused by radiotherapy and chemotherapy.

This invention relates to a use of G-CSF dimer in the treatment of neutropenia. In particular, the recombinant human G-CSF of the present invention can enhance the differentiation and development of neutrophils in animal, and thus effectively reduce the severity of the severe neutropenia and shorten the time of severe neutropenia for the post-chemotherapy cancer patients. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased, providing a better effect in the treatment of neutropenia.