A micro-emulsion containing Vitamin C and Vitamin E and preparation method thereof

A technology of vitamins and microemulsions, applied in medical preparations containing active ingredients, medical preparations with non-active ingredients, and pharmaceutical formulas, etc., can solve problems such as difficult absorption, thermodynamic instability, and difficulty in combined use

Inactive Publication Date: 2006-12-13
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to their different physical and chemical properties, vitamin C is water-soluble, while vitamin E is oil-soluble. There are still some difficulties in the combination of the two, especially when they are applied and used. However, ordinary emulsions have the following disadvantages: (1) the formation of ordinary emulsions generally requires exter

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Component Mass / g

[0043] EL-40 23.08

[0044] IPM 2.05

[0045] Vitamin E 0.51

[0046] Vitamin C 18.59

[0047] Distilled water up to 100.00

[0048] Preparation method: 1) Weigh 23.08g of each component EL-40, 2.05g of IPM, 0.51g of vitamin E, 18.59g of vitamin C, 55.05g of distilled water, and set aside; 2) Put the EL-40 of the stated weight in a container , and then mix the compound oil of IPM: vitamin E=4:1 with EL-40; 3) slowly add 25.0% vitamin C aqueous solution to the container, stir well, the system is colorless and transparent at the beginning, and then With the increase of water, the system has phenomena such as increased bubbles, increased viscosity, decreased transparency, and decreased viscosity. When the amount reaches 9.93g, the system suddenly becomes thin and transparent, and an oil-in-water nanoemulsion is formed.

Embodiment 2

[0050] Component unit / g

[0051] EL-40 21.43

[0052] IPM:jojoba oil=3:1 2.09

[0053] Vitamin E 0.60

[0054] Vitamin C 16.62

[0055] Distilled water up to 100.00

[0056] The preparation method is the same as in Example 1.

Embodiment 3

[0058] Component unit / g

[0059] RH-40 22.66

[0060] IPM 2.01

[0061] Vitamin E 0.50

[0062] Vitamin C 15.70

[0063] Distilled water up to 100.00

[0064] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention discloses a microemulsion containing vitamin C and vitamin E, wherein the continuous phase of the microemulsion comprises vitamin C 0.1-25.0%, vitamin E 0.1-2.0%, and the matrix of the microemulsion comprises surface active agent 9.0-48.0%, oil 1.0-20.0%, and water 40.0-89.0%.

Description

technical field [0001] The invention belongs to the field of medicine and cosmetics, and relates to a microemulsion which can be directly used as cosmetics and medicines, and which can also be added with other active ingredients to form new products, in particular to a microemulsion containing vitamin C and vitamin E. Emulsion and method for its preparation. Background technique [0002] Vitamin C, also known as ascorbic acid, is a trace organic compound necessary for human nutrition and growth. It plays an extremely important role in the body's metabolism, growth and development, and health. If it is lacking for a long time, it will cause physiological dysfunction and certain diseases. Its physiological functions are: vitamin C can promote the formation of collagen, enhance immune function, promote the absorption of calcium and iron, promote cholesterol excretion, prevent atherosclerosis, reduce capillary fragility, decompose histamine, make blood vessels shrink and reduce ...

Claims

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Application Information

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IPC IPC(8): A61K31/375A61K31/355A61K47/30A61K47/14A61P39/06A61P37/02
Inventor 欧阳五庆董红宾
Owner NORTHWEST A & F UNIV
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