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A method for preparing sugar-free granule with astragalus root, dendrobium stem and haw thorn fruit

A sugar-free, granular technology, applied in the field of medicine, can solve the problems of increasing the pollution of medicines, increasing the process, and high cost, and achieving the effects of improving drug safety, simplifying production processes, and reducing production costs.

Active Publication Date: 2006-12-20
葵花药业集团(贵州)宏奇有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Qihuzha granules, because of their bitter taste, are difficult for children to accept, so a large amount of sucrose is added. First, it increases the intake of sugar for children, which undoubtedly increases the risk of diabetes; The dose is too large (each bag contains 8.5g of sucrose extract and 1.5g of a small amount of excipients, 10g each time), which is not convenient for children to take, and the cost is also high
Moreover, in the production process, sucrose needs to be crushed into fine powder before use, which not only increases the process, increases the production cost again, but also increases the possibility of drug contamination

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Weigh the following raw materials: Astragalus 100g, Chinese yam 116.67g, Zhigancao 66.67g, Poria 100g, Dendrobium 83.33g, fried malt 83.33g, hawthorn 106.67g, papaya 83.33g, Codonopsis 93.33g, tangerine peel 66.67g, Atractylodes macrocephala 100g. For the above eleven flavors, take 58.33g of yam, crush it into fine powder, sieve (80-100 mesh), and use the fine powder for later use; add water to the rest of the medicinal materials and decoct three times, add 10 times the amount of water for the first time, and decoct for 2 hours. 1. Add 8 times the amount of water three times, decoct for 1.5 hours, combine the decoction, filter (100 mesh), and concentrate the filtrate to a clear paste with a relative density of 1.25-1.30 (60°C), add yam fine powder, dextrin 650g, Appropriate amount of aspartame and food essence are uniformly mixed, granulated, granulated, dried, and made into 1000g, to be ready.

Embodiment 2

[0020] Weigh the following raw materials: Astragalus 100g, Chinese yam 116.67g, Zhigancao 66.67g, Poria 100g, Dendrobium 83.33g, fried malt 83.33g, hawthorn 106.67g, papaya 83.33g, Codonopsis 93.33g, tangerine peel 66.67g, Atractylodes macrocephala 100g. For the above eleven flavors, take 58.33g of yam, crush it into fine powder, sieve (80-100 mesh), and use the fine powder for later use; add water to the rest of the medicinal materials and decoct three times, add 10 times the amount of water for the first time, and decoct for 2 hours. 1. Add 8 times the amount of water three times, decoct for 1.5 hours, combine the decoction, filter (100 mesh), and concentrate the filtrate to a clear paste with a relative density of 1.25-1.30 (60°C), add yam fine powder, dextrin 700g, Appropriate amount of aspartame and food essence are uniformly mixed, granulated, granulated, dried, and made into 1000g, to be ready.

Embodiment 3

[0022] Weigh the following raw materials: Astragalus 100g, Chinese yam 116.67g, Zhigancao 66.67g, Poria 100g, Dendrobium 83.33g, fried malt 83.33g, hawthorn 106.67g, papaya 83.33g, Codonopsis 93.33g, tangerine peel 66.67g, Atractylodes macrocephala 100g. For the above eleven flavors, take 58.33g of yam, crush it into fine powder, sieve (80-100 mesh), and use the fine powder for later use; add water to the rest of the medicinal materials and decoct three times, add 10 times the amount of water for the first time, and decoct for 2 hours. Add 8 times the amount of water three times, decoct for 1.5 hours, combine the decoction, filter (100 mesh), and concentrate the filtrate to a clear paste with a relative density of 1.25-1.30 (60°C), add yam fine powder, dextrin 750g, Appropriate amount of aspartame and food essence are uniformly mixed, granulated, granulated, dried, and made into 1000g, to be ready.

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Abstract

The invention discloses a process for making sugar-free granules comprising the following steps: disintegrating common yam rhizome 58.33 parts into fines, passing through 80-100 mesh sieve, ;watering and boiling three times, merging the grilling liquid, filtering and concentrating the filtrate into thick grease with specific gravity of 1.25-1.30 (60 deg C), charging common yam rhizome fines and starch gum 650-750 parts, and right amount of flavoring essence, mixing homogeneously, palletizing, granulating and drying.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a preparation method of sugar-free Qihuzha granules. Background technique [0002] For children with symptoms such as anorexia, partial eclipse, excessive sweating, irregular stools, and easy colds caused by deficiency of spleen-stomach qi and spleen dysfunction, Qihuzha Granules can improve the ability of white blood cells to induce interferon and phagocytosis, and the defense ability of patients. Invigorate the spleen and nourish the stomach, replenish qi and solidify the exterior, and promote digestion and stagnation. With the continuous improvement of living standards, people's material life is becoming more and more abundant. Due to many reasons such as unreasonable intake of nutrients and overnutrition, the incidence of diabetes is getting higher and higher, and there is a trend of younger age. Morbidity also occurs from time to time. However, Qihuzha granul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16A61P1/14
Inventor 李新民郝健曹晓军
Owner 葵花药业集团(贵州)宏奇有限公司
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