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Compound medicine for treating diarrheal irritable bowl syndrome

A technology for irritable bowel syndrome and drugs, which can be used in drug combinations, active ingredients of heterocyclic compounds, pharmaceutical formulations, etc., can solve the overall efficacy and tolerance of patients, slowing down the small intestine running time, limited therapeutic effect, etc. To achieve the effect of coordination and complementation of effective effects, reducing dosage and side effects, and improving mental symptoms

Inactive Publication Date: 2007-01-17
张义元 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many methods for the treatment of irritable bowel syndrome at home and abroad, but most of them are effective for relieving a single symptom of some patients, and are not satisfied with the overall curative effect and tolerance of patients.
Domestic scholars use traditional Chinese medicine, Western medicine combined with diet, psychotherapy and other comprehensive measures, the treatment is long, easy to relapse, and the effect is not good
In foreign countries, drug treatment is the main method, and there are many kinds of drugs, but the therapeutic effect is limited. For example, anticholinergic drugs, analgesics, were widely used at one time, but now many people think that they do more harm than good.
Diphenhydramine or loperamide, which should not be used long-term because of the possible development of resistance to the antidiarrheal effect
The 5-hydroxytryptamine receptor antagonist alosetron, etc., can slow down the transit time of the small intestine and colon, increase the threshold of visceral pain, and reduce the secretion of the small intestine. limit

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1. Zhang Mou, female, 27 years old, civil servant. Repeated abdominal pain and diarrhea for 11 years, aggravated in the past six months. It occurs in the morning, and there is no discomfort after diarrhea. It can also occur after eating cold or bad mood. Sometimes the diarrhea reaches more than 10 times a day, which seriously affects work and study. But soon, after taking the medicine of the present invention for 1 course of treatment, diarrhea disappeared, and no recurrence was seen in 3 years by follow-up visits.

Embodiment 2

[0033] Example 2. Mr. Wang, male, 20 years old, high school student. Repeated abdominal pain, diarrhea for 3 years, aggravated January to the doctor. After getting up in the morning and after breakfast, I defecate once, sometimes the study stress or before the exam, the number of diarrhea increases, does not affect eating and growth, taking digestive aids, antibiotics and antidiarrheal drugs is invalid, after taking the medicine of the present invention for 1 course of treatment, symptoms disappear, follow up visits 1.5 years without recurrence.

Embodiment 3

[0034]Example 3. Mr. Zhao, male, 36 years old, cadre. Repeated abdominal pain and diarrhea for 6 years, aggravated in March. Diarrhea started at dawn, defecation once after breakfast, seizures after eating carelessly, no discomfort after defecation, mostly 5-8 times a day, no weight loss, taking a variety of drugs ineffective, once taking alosetron, but because of Severe constipation was discontinued, and after taking the medicine of the present invention for 1 course of treatment, the symptoms disappeared, and no recurrence was seen in 2 years by follow-up visits.

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PUM

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Abstract

A compound medicine in the form of capsule for treating diarrhea-type irritability syndrome is prepared from 7 Chinese-medicinal materials including pilose asiabell root, tuckahoe, white peony root, coptis root, etc, vimicon, VB and thiaminogen through respective grinding, proportional mixing, sieving, and filling it in capsules.

Description

Technical field [0001] The invention relates to a compound medicine for clinical application in medicine, in particular to a compound medicine combining traditional Chinese and Western medicine for treating diarrhea-type irritable bowel syndrome. Background technique [0002] Irritable bowel syndrome is a common and frequently-occurring disease that seriously endangers human health. Epidemiological surveys on irritable bowel syndrome at home and abroad show that the incidence rate in my country is 5.6-10.1%, the incidence rate of digestive clinics in line with irritable bowel syndrome reaches 34.3%, and the incidence rate in western countries reaches 10-22%. The high incidence is between the ages of 18 and 30. There are more women than men, about 1.5-1.9:1. There are more students, cadres and intellectuals than workers and farmers, and more patients in urban areas than in rural areas. Diarrhea-type irritable bowel syndrome patients have diarrhea several or ten times a day, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P1/12A61K31/51A61K31/445A61K31/575
Inventor 张义元李凤婷
Owner 张义元