Imiquimod turbid liquor and gelling agent thereof

Abstract

The invention relates to a climiqualine suspension and relative production, and relative medicine, as climiqualine gel. Wherein, it uses the mixture solvent of glycerin, alcohol and boracic acid solutions, to obtain stable and uniform climiqualine suspension, to make gel agent, etc.

Description

technical field

[0001] The invention relates to an imiquimod suspension solution and a preparation method thereof, and a pharmaceutical preparation containing the imiquimod suspension solution, especially an imiquimod gel and a preparation method thereof. It belongs to the field of medicine. Background technique

[0002] Condyloma acuminata is a sexually transmitted disease, which is caused by human papillomavirus infection. The incidence rate is second only to gonorrhea, and it is the second most common sexually transmitted disease. Currently there is no effective drug for the treatment of genital warts. The treatment methods that can be used clinically have caused great misery to patients, and the recurrence rate is extremely high.

[0003] Imiquimod is an immunomodulatory drug, which belongs to the non-nucleoside isocyclic amine drugs. It has been widely used clinically for external genital and perianal condyloma acuminatum caused by human papillomavirus infection. Im...