Immunoglobulin for resisting O and Asia I type foot and mouth disease used for cow and pig

Abstract

The invention relates to an immunity globulin used to prevent O-type and I-type foot-and-mouth diseases, of cow and pig, wherein it mixes foot-and-mouth disease O-type and I-type antigens in 1-2:1-2 volume ratio; mixes Freund's adjuvant with immunogen at 1:1 volume ratio; uses glycosides injection as immunity strengthener. The inventive production meets the standard of national animal biological product standard (2000 version). And it can prevent O-type and I-type foot-and-mouth diseases.

Description

technical field [0001] The invention belongs to the field of biotechnology, and specifically relates to the preparation of immunoglobulins for treating and preventing type O and Asian type I pig foot-and-mouth disease by using two immunogens. The international patent classification number is: A61K39 / 395. Background technique [0002] Foot-and-mouth disease (FMD) is an acute and severe infectious disease of ruminants. Artiodactyls such as cattle and pigs are susceptible, and humans can also be infected. The disease seriously threatens the domestic and foreign trade of artiodactyls and their products as well as human health. Once the foot-and-mouth disease breaks out, the disease inspection, isolation, extermination, and epidemic prevention will bring great economic losses to the country. [0003] There are currently 7 serotypes of foot-and-mouth disease virus, including O, A, and Asia I. my country's pig and cattle foot-and-mouth disease are mostly type O and Asian type I, ...

AI Technical Summary

Problems solved by technology

[0012] In the case of foot-and-mouth disease, inactivated vaccines for foot-and-mouth disease are used for immunization prevention in the form of a circular enclosure. Because the blockade may be lifted 30 days after immunization, it adds great difficulties to the isolation and prevention. Within 30 days, the animals in the isolation zone may be There is also the possibility of infection and escape to the outside of the encirclement