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Method of collecting bone marrow and medical device for use therein

A collection method and technology for medical devices, applied in the field of catheters, medical devices, and puncture needles, can solve problems such as difficult and rigid puncture needles, and achieve the effect of reducing burden and efficiently attracting bone marrow

Inactive Publication Date: 2007-07-04
HI-LEX CORPORATION +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, even if this operation is performed simultaneously with X-ray fluoroscopy, it is difficult to reliably penetrate straight into the shaft of the bone canal in three dimensions. It is extremely difficult to reach the bone marrow cavity from the greater trochanter only with a rigid needle difficult

Method used

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  • Method of collecting bone marrow and medical device for use therein
  • Method of collecting bone marrow and medical device for use therein
  • Method of collecting bone marrow and medical device for use therein

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0167] A curved puncture needle with a radius of curvature of 5 cm was made of hard stainless steel by combining an outer needle with an outer diameter of 2.2 mm, an inner diameter of 2 mm, and a length of 7 cm, and a solid inner needle with an outer diameter of 1.9 mm and a length of 7.2 mm. Its tip is made into a three-sided cone. The inner needle and the outer needle are in an interlocked state at the proximal end of the part opposite to the tip, and are locked when turned slightly clockwise, and released when turned counterclockwise. Use it as a bone marrow needle for testing.

[0168] A detection tube with an outer diameter of 2.2 mm, an inner diameter of 1.5 mm and a length of 12 cm is made of polyethylene. The probe tube is flexible and has sufficient strength to penetrate into the cancellous bone.

[0169] A catheter made of polyethylene with an outer diameter of 2.2 mm, an inner diameter of 2 mm, and a length of 25 cm was prepared. Bends of 120 degrees were applied...

Embodiment 2

[0180]Another dog weighing 20 kg was also used for bone marrow collection in the Department of General Anesthesia. This time, the same puncture needle, probe tube, catheter, guide wire, etc. as in Example 1 were prepared. However, as the catheter, a double-lumen catheter was prepared, which is a circular main pipe with an outer diameter of 2.2 mm and an inner diameter of 1.4 mm as in Example 1, and a thin gap with a thickness of 0.4 mm provided on its side. side pipe.

[0181] These two tubes were respectively connected with a three-way piston at the proximal end, and in a state where drip injection was possible, each was connected to an infusion bag filled with saline via a connecting tube, and the catheter was filled with saline. A part of the three-way plunger with a backflow prevention valve used in vascular catheter operations. The catheter has a side hole 0.7 mm from the tip, leading to a main tube with an inner diameter of 1.4 mm. In addition, 120-degree bends were a...

Embodiment 3

[0188] Bone marrow puncture was performed on animals in order to see the effect of using a puncture needle without an inner needle, although the puncture needle also had a bend. The puncture needle used only has an outer needle with an outer diameter of 2.2 mm, an inner diameter of 2 mm, and a length of 7 cm, without an inner needle. Its tip is made into a three-sided cone. At 5 mm from the tip, a side hole with a width of 0.6 mm and a length of 2 mm was provided inside the bend of the needle. The proximal end of the needle is made into a structure capable of installing a syringe. The same device as in Example 2 was used for the guide wire and probe tube used at the same time, and a catheter with a curved structure at the tip was used in the double lumen.

[0189] First, the animal was placed in the left decubitus position in the same manner as in Example 2, and the greater trochanter of the left femur in the left waist was confirmed by palpation under clean conditions, and ...

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Abstract

Using a bended puncturing needle, a through hole from the greater trochanter of a long tubular bone to the bone marrow cavity is formed, the catheter 61a, 61b is passed into the through hole, a physiological salt solution is injected from one of the catheter 61b, and the physiological salt solution and the bone marrow is stirred by the stirring wire 68, the obtained mixed liquid is aspirated and harvested by another catheter 61a, thereby a large amount of the bone marrow is harvested. A method enabling easy and a large amount harvesting of the bone marrow from long tubular bones such as femurs, in which a multi-lumen catheter can also be used as a catheter.

Description

technical field [0001] The present invention relates to a bone marrow harvesting method and a medical device used in the method. More specifically, it relates to a method for harvesting bone marrow from the medullary cavity of a long tubular bone, and a puncture needle, a catheter and a medical device suitable for the method. Background technique [0002] Non-Patent Document 1: Thomas et al.: Technique for human marrowgrafting. Blood, pp.507, 1970 [0003] Non-Patent Document 2: Ikehara et al.: A new method for bone marrow cell harvesting. Stem Cells, 18:6, pp453, 2000 [0004] Non-Patent Document 3: Japanese Society of Computer Surgery 2001 Report pp. 101-102 Kota Ohashi et al.: Development of Low-invasive Bone Marrow Collection Device (First Report: Research on Femur Bone Marrow Collection Device: Puncture Needles and Collection Instruments for Bone Marrow Collection and bone marrow collection method) [0005] Patent Document 1: U.S. Patent No. 5,368,046 [0006] Paten...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B10/00A61B17/34A61M1/00A61B10/02A61B17/22
CPCA61B2017/320733A61B2010/0258A61B10/025
Inventor 野一色泰晴藤田康弘饴谷彰洋关康夫
Owner HI-LEX CORPORATION
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