Composition for reducing food intake
a technology of food intake and composition, applied in the field of composition for reducing food intake, can solve the problems of zotrim's effect on human food intake, feeding behaviour and subjective appetite and satiety, and the effect of reducing appeti
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example 1
Materials and Methods
[0037]Study Design. This was a double-blind, placebo-controlled study using a randomized within-subject design to evaluate the effects of ZOTRIM and inulin fiber given together, separately and against placebo control in terms of food intake in grams and kilocalories and subsequent food ratings measured using visual analogue scales (VAS) of hunger, fullness, prospective consumption, desire to eat and satisfaction pre dosing, pre and post meals and at hourly intervals across the day. The independent variables were the four conditions-ZOTRIM (tablet form) and inulin fiber (powder mixed with water), ZOTRIM and control, inulin fiber and placebo and control and placebo. The dependant variables were food intake measured in grams, kilocalories and macronutrients and the VAS ratings. All food and water was recorded by weight scales (Sartorius Model CPA 4202S, Sartorius Ltd, Epsom, UK; 0.1 gram accuracy) before and after meals to ascertain intake in grams, kilocalories an...
example 2
Herbal Extracts and Inulin Decrease Food Intake
[0060]Fifty-eight healthy average to slightly overweight women were recruited to the study through advertising. A double blind, placebo-controlled, cross-over design was employed. After screening, eligible participants were invited to the laboratory on four separate occasions for breakfast and lunch. The study days were arranged according to the participants' availability and always leaving a minimum of two days between each visit. On study days, the participants were administered the first dose of ZOTRIM and inulin fiber (5.8 g), ZOTRIM and water, inulin fiber and placebo or water and placebo, 15 minutes before a fixed load breakfast. Four hours after the initial dose, and 15 minutes before lunch, the second dose of the same condition was given. The dose was composed of three tablets, either ZOTRIM (a dose having 336 mg of yerba mate leaf extract, 285 mg of guarana seed extract and 108 mg of damiana leaf extract) or a placebo, and a hu...
example 3
[0078]Studies are conducted with male Sprague-Dawley rats weighing 270-290 grams. Three days before the start of an experiment, the animals are weighed and individually housed. Normal rat chow pellets and tap water are present ad libitum and are provided by food troughs and drinking spouts, which allow continuous recording of the food consumed. Compositions containing plant extracts+inulin are administered at predetermined times to the treatment group. Food intake is recorded by continuously weighing the amount of food remaining in a round stainless steel food basket. Food intake is continuously or intermittently recorded over the entire time of an experiment. The weight of each animal is determined on each day of the experiment and recorded, together with any unusual observations, e.g., stressed animals, difficulties with plant extract application, etc. Statistical analysis to detect differences in ingestive behaviour between the control group and the tr...
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