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Bioactive Dairy Products and Processes for Their Manufacture

a technology applied in the field of bioactive dairy products and processes for their manufacture, can solve the problems of increasing the processing cost of colostrum, diarrhoea, inflammation, sepsis, etc., and achieve the effect of positive health benefits

Inactive Publication Date: 2020-08-20
INNOVATIVE DAIRY CONSULTANTS LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent describes a liquid or semi-liquid bioactive dairy composition that includes a bioactive powder made of colostrum powder and / or milk powder, and immunoglobulins. The composition also contains a food grade acid, such as citric acid, and a sweetening agent. The composition has a pH of between 2.5-4.0 and is heated-treated. The patent also describes a ready-to-eat or ready-to-drink food product that contains the bioactive composition. The technical effects of the invention include providing a bioactive dairy composition with a specific pH range and heat treatment that retains its bioactive properties, as well as a food product that contains the bioactive composition.

Problems solved by technology

In the case of hospital patients, gastrointestinal infections, side effects of chemotherapy etc. may result in clinical symptoms of diarrhoea, inflammations, sepsis etc.
Bovine IgG from colostral whey has been shown to be stable at neutral pH but with decreasing pH the stability is deteriorated (Chao-Cheng Chen et al, 1998).
Using known methods, utilization of such heat stable immunoglobulins in formulations, especially on a commercial scale would first require removal of casein, substantially increasing the processing cost for colostrum and also resulting in the loss of an important nutrient.
U.S. Pat. No. 8,062,687 B2 describes a method of preparation of a beverage having high residual IgG but this is based on high pressure processing (HPP) technology which entails high cost of capital equipment which is not commercially viable, especially for small or medium scale manufacturers.
Moreover, depending on the operating parameters and the scale of operation, the cost of high-pressure treatment is very high compared to the cost of thermal processing (Thakur and Nelson, 1998; Balasubramaniam, 2003).
Moreover, these powders and tablets cannot be used in preparing products that have much longer shelf life under ambient conditions and greater consumer appeal, like UHT “Ready to drink” (RTD) acidified beverages with enhanced palatability, carbonated drinks, fermented dairy foods-UHT drinking yoghurt, set / stirred yoghurt, long life yoghurt, UHT juice milk drinks, drinking yoghurt with “live organisms”, acidified milk spreads / sauces, ice cream and related products, frozen yoghurt, desserts, flans, cheese, tea / coffee, etc.

Method used

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  • Bioactive Dairy Products and Processes for Their Manufacture
  • Bioactive Dairy Products and Processes for Their Manufacture
  • Bioactive Dairy Products and Processes for Their Manufacture

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0229]Table 1 gives the composition of the bioactive powder used in the formation of the bioactive dairy composition, which may also be utilised directly as a beverage. In one composition (left column of the table) the IgG content is 20-21% in the bioactive powder. The ratio of whey proteins to IgG is approximately 3:1 by weight. The IgG activity retained in the bioactive dairy composition prepared therefrom (according to the process of FIG. 1) and heated at 86° C. / 30 sec is 45.8% at pH 3.1-3.3 while at pH 3.4-3.6 it is much lower, i.e. 29.2%.

[0230]In the other composition (right column of the table) the IgG content of the bioactive powder is 25-27% and the ratio of whey proteins to IgG is approximately 2:1. The IgG activity retained in the beverage prepared therefrom after heating under similar conditions is 37.2% at pH 3.1-3.3, while at pH 3.4-3.6 it is slightly higher, i.e. 41.0%. However, at neutral pH (6.4-6.6), under similar conditions of heat treatment, the IgG activity retai...

example 2

[0232]UHT Dairy Beverage Enriched with IgG and Lecithin

[0233]Another embodiment of the invention is related to the inclusion of lecithin in the bioactive powder at 0.5-8% by weight, preferably between 1.5-2.0%. Lecithin may be added to the bioactive powder before or after drying. It is preferred to add the lecithin before drying. If it is desired to enhance the lecithin content of the finished product, lecithin powder may be dry blended with the bioactive powder.

[0234]Alternatively, lecithin may also be added to the dairy beverage during processing (FIGS. 2 and 3). This may be soy or sunflower lecithin. The compositional details of the bioactive powder used and the bioactive dairy beverage made after heat processing at 84-92° C. / 15 sec are given in Table 2. The ratio of whey proteins to IgG is approximately 3:1 in the bioactive powder having 60-65% whey protein and 20-21% IgG. In the bioactive powder (4.5% by weight in the beverage) having 47-51% whey protein and 25-27% IgG, the rat...

example 3

[0238]An acidified beverage having honey can be made from a bioactive powder. Incorporation of honey significantly enhances the nutritive and therapeutic value of the beverage as it is well known for its anti-inflammatory, antioxidant and immune-stimulatory activity. Any pure honey including but not limited to “Creamed honey” and “Manuka Honey” (Made in New Zealand) may be used.

[0239]A UHT beverage (heated at 87° C. / 15 sec) was made from bioactive powder having 1.5% lecithin with the sucrose in the formulation replaced partially with “Manuka” honey (A pure natural New Zealand honey) at 1% dosage and stevia at 0.016% in the formulation, according to the method outlined in FIG. 3. As shown in Table 3 it was possible to retain about 96% activity of IgG after processing at pH 3.2-3.3.

TABLE 3UHT dairy beverage having honey, enriched with IgG and lecithinIngredients% By weightBioactive powder (Fat 1.1%, Protein 85.02%,3.5Casein34.52%, Whey Protein 50.5%, IgG 26.38%,IgG (Minus casein) 16.1...

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Abstract

The invention relates to a liquid or semi-liquid bioactive dairy composition formed from a bioactive powder containing a colostrum powder and / or milk powder and immunoglobulin G (IgG), water and a food grade acid; the composition having a pH between 2.5-4.0. The bioactive dairy composition can be used in the preparation of a range of ready-to-drink and ready-to-eat food products having bioactive properties. Processes for the preparation of the bioactive dairy composition and the associated food and beverage products is also described.

Description

FIELD OF INVENTION[0001]This invention relates to bioactive dairy products and processes for their manufacture. More specifically, the invention relates to formulations and processes for the production of ready-to-eat or ready-to-drink dairy products containing bioactive immunoglobulin G (IgG).BACKGROUND TO THE INVENTION[0002]The proteins found in milk include immunoglobulins, growth factors, bovine serum albumin, (BSA), alpha lactalbumin, beta lactoglobulin and a large number of caseins and growth factors (IGF-Insulin-like Growth Factor and TGF-Transforming Growth Factor). However, the concentration of digestive enzymes, immunoglobulins, cytokines, interferons, growth factors, glycoproteins, proline-rich peptides and vitamins A, D, E and K are all higher in prime colostrum compared to standard milk.[0003]Immunoglobulins (Igs), or antibodies, are a group of glycoproteins present in serum and tissue fluids of all mammals. There are five isotypes of Igs which all have a similar basic ...

Claims

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Application Information

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IPC IPC(8): A23C9/152A61K35/741A61K35/20A61K9/00A23C9/20A23C9/16A23C9/156A23C3/02A23C9/13A23L2/38A23L2/54A23G9/38A23G9/40A23G9/42A23G9/52A23L33/19
CPCA23C9/1307A23V2002/00A23G9/38A61K35/741A23C9/1565A61K35/20A23C9/206A23C3/02A23C9/16A23G9/52A23G9/40A23C9/1528A23G9/42A23L33/19A23C9/1315A23L2/382A23L2/54A61K9/0056A23C9/1526A23C9/152A23L29/281A23L2/38A23V2250/032A23V2200/06A23V2250/5434A23V2200/324A23V2300/24A23G2200/12A23V2250/1842A23G9/32A23L33/10A23C21/06A61K35/00A23G9/363
Inventor BHANDARI, VIVEK
Owner INNOVATIVE DAIRY CONSULTANTS LTD