The application belongs to the technical field of food, and particularly relates to a
beta lactoglobulin powder with low allergenicity and a preparation method thereof. The preparation method of the
beta lactoglobulin powder comprises the following steps: adjusting the pH of a beta-lactoglobulin solution to be acidic; adding an
oligosaccharide solution to the beta-lactoglobulin solution with changed pH, stirring uniformly to obtain a beta-lactoglobulin-
oligosaccharide mixed solution; performing freeze-
drying to obtain a mixed
powder; placing the mixed powder in a condition of a temperature of 50-60 DEG C and a
relative humidity of 70-80% to perform a
Maillard reaction; and finally, dissolving, dialyzing and freeze-
drying the mixed powder to obtain a low-allergenic beta-lactoglobulin powder. The preparation method can effectively destroy the allergenic
epitope of beta-lactoglobulin, significantly reduces the allergenicity of beta-lactoglobulin, and improves the
solubility and foaming property of beta-lactoglobulin while reducing the allergenicity of beta-lactoglobulin.