58results about How to "Reduce the incidence of allergic reactions" patented technology

The invention discloses a three-dimensional kidney neoplasm surgery simulation method and a platform based on a computed tomography (CT) film. The method includes that firstly, a data base including object resources is built, multiple manners including CT film scanning are inputted into a CT faultage image, a sequence image is registered according to the sequence based on an outline gradient principle, a registered CT image is utilized to reconstruct segmentation tissue of an arterial phase, a venous phase and a lag phase by adopting of a three-dimensional reconstruction technology, and the segmentation tissue of the arterial phase, the venous phase and the lag phase are effectively fused in the same coordinate space. According to an imaging staging criteria and a treatment guideline of kidney neoplasm, and based on modeling results, various peration plan designing, operation stimulation, surgical risk analysis and response, and prognostic analysis are carried out, a personalized and benefit maximization treatment plan can be provided for an object, and skills and degree of proficiency of an operation can be improved, and the three-dimensional kidney neoplasm surgery simulation method can be used in medical teaching.

The invention discloses a preparation method of a thymopetidum injection, comprising the following steps of: mixing and grinding thymic tissues of calves or pigs and an aqueous sodium chloride solution; regulating a pH value to 3.5-4.5; freezing at the temperature from 15 DEG C below zero to 22 DEG C below zero; thawing and heating frozen mixed and ground fluid to the temperature of 33-37 DEG C; homogenizing the liquid to obtain homogenate; heating the homogenate to the temperature of 80 DEG C; insulating for 30 minutes; separating to obtain supernatant fluid; mixing the supernatant fluid and ethanol; standing; separating again; concentrating; regulating a pH value of concentrated fluid to 7.5-8.5; then, heating the concentrated fluid to the temperature of 80 DEG C; insulating for 30 minutes; cooling and centrifugally separating to obtain third supernatant fluid; after hyperfiltering and clarifying by an ultrafiltration membrane step by step, obtaining a thymopetidum solution; adding water for injection into the thymopetidum solution in order to regulate thymopetidum content of 2.5mg or 5mg or 10mg in each milliliter of the thymopetidum solution; adding a stabilizing agent; and obtaining the thymopetidum injection after being sterilized. In the prepared thymopetidum injection, the content of high polymer substances is smaller than 0.5 percent and is further lower than a standard rule of China.

The invention belongs to the field of medicine, and provides a compound amino acid dipeptide injection, a preparation method thereof and an application thereof, the injection comprises three cavity bags, the three cavity bags are respectively separated by three bags and filled with a branched-chain amino acid solution, a L-alanyl-L-glutamine solution, and a mixed solution containing arginine hydrochloride and vitamin B6; wherein, in every 1000 mL of the injection solution, the total mass of the amino acid is 50 g to 130 g; and the branched chain amino acid mass accounts for 10 to 80% of the total mass of the amino acid; the mass of L-alanyl-L-glutamine is 5 to 70% of the total mass of the amino acid; the mass of arginine hydrochloride is 0 to 50% of the total mass of the amino acid; and the mass of the vitamin B6 is 0 to 1 g. The injection of the invention improves the stability and effectiveness of the product while providing product safety, and the technical scheme is simple and convenient for industrial production.

The invention provides a stable amoxicillin tablet composition, as well as a preparation method and application thereof. The preparation process adopts a technology of directly tabletting powder. The amoxicillin tablet composition has the advantages that: the problems of amoxicillin tablet dissolution and product stability can be effectively solved, the influence of temperature and humidity on product quality can be avoided, generation of macromolecule impurities can be reduced, and the occurrence rate of anaphylactic reaction can be reduced, so that the clinical application safety can be improved, and the patient compliance can be improved.

The invention belongs to the field of cosmetics with special purposes and in particular relates to folium artemisiae argyi flavone freckle-removing gel. The folium artemisiae argyi flavone freckle-removing gel is characterized by being prepared from the following components in parts by weight: 23 percent to 26 percent of folium artemisiae argyi extract, 4.5 percent to 5.5 percent of water-solubleazone, 0.8 percent to 1.2 percent of a gelling agent, 1 percent to 1.5 percent of a humectant, 2 percent to 3 percent of a surfactant, 0.5 percent to 1 percent of a co-surfactant and the balance of purified water which is added until the content is 100 percent. The folium artemisiae argyi flavone freckle-removing gel provided by the invention has the advantages that a production technology of thefolium artemisiae argyi extract is simple, the consumption of organic solvents is less and the variety of flavones in a product is abundant; the content of the flavone in the folium artemisiae argyi extract is detected by adopting an ultraviolet spectrophotometry and is 21.3 percent to 27.5 percent. Folium artemisiae argyi oil has an anti-allergic effect; when the content of the folium artemisiaeargyi oil is relatively low, the anaphylactic reaction probability in a utilization process is easy to reduce; after a transdermal agent azone is added, the folium artemisiae argyi flavone can easilydirectly act on freckles through skin and the metabolism of skin cells is accelerated, so that the effects of realizing freckle fading and preventing new freckles from being generated are realized.

The invention is calf dehemoglobinize extract transfusion and its manufacturing method. The amino acid and small peptide in the extract of the calf dehemoglobinize can be polymerized into high molecular peptide and large molecular weight peptide, thus the medicine has antigenicity and reduces the biology activity of the medicine, and causes the increase of clinic hypersusceptibility. The ingredients of the calf dehemoglobinize are: the calf dehemoglobinize extract and osmotic pressure regulator, the calf dehemoglobinize extract is extracted from the calf blood or blood serum, the extract solid contains nitrogen and amino acid, its weight shares are: amino acid is 20.0-30.0, the nitrogen 12.5-18.75, the osmotic pressure regulator 50-100, pH value is 5.5-8.0, the product is a little yellow or yellow transparent liquid. The product can be applied to cure cerebral ischemia, cerebral dementia, brain trauma and incompetence of brain fucntiosn, and so on, they are all brain cell metabolism handicap diseases; it also can be applied to cure the twig artery, vein circulation obstruction, and artery angiopathy.

The invention discloses a traditional Chinese medicine composition. The composition is prepared from the following raw materials in parts by weight of 20-60 parts of fibrilia, 15-35 parts of vegetableoil, 20-28 parts of animal oil, 5-15 parts of herba lycopodii, 10-30 parts of radix angelicae pubescentis and 10-35 parts of radix salviae miltiorrhizae. The composition has the following beneficialeffects that the vegetable oil and the animal oil are mixed to improve the permeability and adhesion of the medicines to the skin, especially the adhesive animal oil is sticky and changes patient allergic components in a formula after being mixed with the medicines, the content of the allergic components is reduced to current 0.5% from original 1.5%, and the composition has the strange effect forkneesynovitis, spur and meniscus tear.

The invention discloses a preparation method of a transfer factor. The preparation method of the transfer factor is characterized by comprising the steps: pre-processing, homogenation, repeated freeze thawing, centrifugation, ethanol precipitation, primary ultra-filtration, virus inactivation and secondary ultra-filtration. The invention also discloses a preparation method of a transfer factor injection. According to an ethanol precipitation method and a virus deactivation method which are not adopted in a traditional process, various impurity proteins are removed, and various animal source viruses are effectively removed, so that the security of products can be effectively guaranteed, sensitive sources are reduced, and the security is improved; meanwhile, by adopting an ethanol precipitation method, the impurity proteins are removed, so that the ultra-filtration load of a subsequent ultrafiltration membrane can be reduced, and the service life of the ultrafiltration membrane is prolonged.

The invention relates to a ceftriaxone sodium compound and a preparation method thereof. The compound comprises active ingredient ceftriaxone sodium, impurities and ceftriaxone polymer, wherein the content of ceftriaxone sodium is not less than 90.0% by calculation on the basis of an anhydride, the total weight percent of the impurities is not larger than 0.1% on the basis of the weight percent of ceftriaxone, the impurities comprise 7-ACT and triazine ring, and the weight percent of the ceftriaxone polymer is not larger than 0.1% on the basis of the weight percent of ceftriaxone. The preparation method of the compound is simple, economical and environment-friendly, the contents of the impurities and the polymer in a product are low, adverse reactions are remarkably reduced, and safety of clinical medication of a ceftriaxone sodium preparation can be guaranteed well.

The invention provides an interior wall coating. The coating comprises the following components in parts by weight: 10-40 parts of a silicate, 0.1-0.5 part of a dispersant, 20-40 parts of titanium dioxide, 0.1-0.5 part of an anti-foaming agent, 10-30 parts of water, 10-20 parts of a degradable emulsion, 0.1-0.5 part of cellulose, and 0.3-1 part of a silicate stabilizer, wherein raw materials of the degradable emulsion comes from fruit extracts of gramineous plants. The interior wall coating adopts the fruit extracts of the gramineous plants as the main preparation raw materials for the degradable emulsion, residual monomers in the emulsion are avoided, performances of a traditional interior wall coating can be reached, and main allergens (preservatives, mould inhibitors, film-forming auxiliary agents, antifreeze agents and residual monomers in the emulsion) are excluded, so that the probability of allergic reactions of skin contactors or respiratory inhalers is reduced. The invention also provides a preparation method of the interior wall coating.

The invention belongs to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition with whitening effect and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following fresh raw materials in parts by weight: 100-750 parts of fresh raw radix astragali, 50-350 parts of fresh radix astragali zymophyte, 30-350 parts of raw radix polygoni multiflori, 20-350 parts of diospyros lotus fruits, 30-350 parts of rhizoma polygonati odorati, 30-500 parts of fructus chaenomelis, 30 to 400 parts of fig, 30 to400 parts of rubus idaeus fruits, 30 to 400 parts of herba taraxaci, and 10-300 parts of black propolis. The traditional Chinese medicine composition and the preparation method have the beneficial effects that (1) in comparison with dry traditional Chinese medicine compositions, the clinical efficacy of the extract of the fresh traditional Chinese medicine composition is obviously improved; (2) the diospyros lotus fruits are added to the traditional Chinese medicine composition, and thus the whitening effect is obviously improved.

The invention belongs to the technical field of medicinal preparations, and concretely relates to a lidocaine hydrochloride compound medicine injection and a preparation method thereof. The injection comprises 8mg/ml of lidocaine hydrochloride, 1.3mg/ml of menthol, 2.0mg/ml of sodium chloride, 0.05ml/ml of glycerin, 1.33ml/ml of ethanol and 0.001-0.01mg/ml of polyethylene glycol-12-hydroxystearate. The compound injection has the advantages of excellent long-acting anaesthesia effect, stable medicinal preparation, no hemolysis and low allergy.

The invention discloses narrow-distributed hydroxyethyl starch and application thereof. The weight-average molecular weight Mw of the narrow-distributed hydroxyethyl starch is 250000-400000; the molar substitution degree MS of the narrow-distributed hydroxyethyl starch is 0.3-0.7; the ratio of C2 to C6 is 4-12; the narrow-distributed hydroxyethyl starch can be used as a reagent of a medium for animal tissue or human body tissue density separation, and particularly a medium for blood density separation. By improving key molecular weight distribution of hydroxyethyl starch, such as the weight-average molecular weight Mw, the molar substitution degree MS and the ratio of C2 to C6, compared with the prior art, the narrow-distributed hydroxyethyl starch can be used as a novel medium for animal tissue or human body tissue density separation, so that the problems that a cell separation liquid has toxicity for cells, cell activity can be affected and the like can be effectively solved.

The invention relates to the field of medicine purification, and in particular, relates to a cefaclor impurity removal method which comprises the following steps: S1, weighing a cefaclor compound, anddissolving the compound in an organic solvent; S2, filtering and separating the organic solvent, and extracting the organic solvent containing cefaclor; S3, adjusting the acid-base value of the organic solvent and adjusting the temperature of the organic solvent, and performing secondary filtration by utilizing an adsorbate; S4, putting the adsorbate into a mixed solution of a low-carbon solventand water, and crystallizing cefaclor adsorbed on the adsorbate. According to the cefaclor impurity removal method, cefaclor impurities are put in the organic solvent for dissolving, cefaclor insoluble in water can be dissolved in the organic solvent, the organic solvent of cefaclor is separated, filtered and extracted, the pH value is controlled, cefaclor particles with low impurity content are obtained, and the occurrence rate of allergic reaction possibly caused by excessive impurities of medicines is reduced.

The invention discloses a traditional Chinese medicine for treating sacral canal cyst, lymphatic accumulation and nodule, and a preparation method thereof. The traditional Chinese medicine is prepared from, by weight, 5-6 parts of fibrilia, 5-6 parts of animal oil, 4-15 parts of radix angelicae, 4-15 parts of radix angelicae pubescentis and 6-8 parts of antler. According to the invention, the animal oil is adopted, so that the permeability and adhesive force of the medicine to the skin can be increased, particularly the adhesive animal oil is sticky, the allergic components of a patient in the formula are changed after the medicines are combined, and the traditional Chinese medicine has the characteristics of short treatment time, quick effect, thorough rehabilitation and low allergic reaction rate in the treatment of sacral canal cyst, lymphatic accumulation and nodule.