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Folium artemisiae argyi flavone freckle-removing gel

A technology of wormwood flavonoids and freckle removal, applied in cosmetics, skin care preparations, cosmetic preparations, etc., can solve problems such as not being suitable for long-term use, and achieve the effect of preventing new freckles from forming, simple production process, and lightening freckles

Inactive Publication Date: 2018-03-02
马述腾
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Artemisia argyi essential oil contains toxic ingredients, such as thujone, so it is not suitable for long-term use

Method used

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  • Folium artemisiae argyi flavone freckle-removing gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Purchase 100 kg of fresh wormwood whole herb, manually remove withered leaves, cut off the roots, wash the sediment, dry, chop, grind with a colloid mill, and collect 93.5 kg of homogenate. 50°C, natural pH value, add 0.94kg cellulase powder, stir evenly, enzymatically hydrolyze for 24h, heat and extract the enzymolyzed solution by steam distillation, reflux for 4h, the distillate is 0.9L crude extract of mugwort leaf oil. Use a 200 mesh nylon mesh to filter the distillate after distillation to obtain 39.67 kg of filtrate. After spray drying, 9.41 kg of raw material coarse powder is obtained. Dissolve 188.2 kg of dissolved raw material coarse powder with 60% ethanol solution, stir until fully dissolved, and obtain alcohol extraction liquid, use a membrane with a pore size of 45 μm to carry out suction filtration, and retain the suction filtrate. Use a modified cellulose membrane with a molecular weight cut-off of 30kD to carry out ultrafiltration to remove impurities fr...

Embodiment 2

[0032] Purchase 200kg of fresh wormwood whole herb, manually remove the withered leaves, cut off the roots, wash the sediment, dry, chop, grind with a colloid mill, and collect 189.6kg of homogenate. 50°C, natural pH value, add 3.5kg cellulase powder, stir well, enzymolyze for 24h, heat and extract the enzymolyzed solution by steam distillation, reflux for 5h, the distillate is 1.61L crude oil of mugwort leaves. Use a 200-mesh nylon mesh to filter the distillate after distillation to obtain 83.52 kg of filtrate. After spray drying, 19.15 kg of raw material coarse powder is obtained. Dissolve 385 kg of dissolved raw material coarse powder with 60% ethanol solution, stir until fully dissolved, and obtain an alcohol extract , use a membrane with a pore size of 45 μm for suction filtration, and retain the suction filtrate. Use a modified cellulose membrane with a molecular weight cut-off of 30kD to carry out ultrafiltration to remove impurities from the suction filtrate, add an eq...

experiment example

[0034] There were 216 cases of volunteers, including 72 cases of mild, moderate and severe cases (mild: the pigmentation is light brown, accounting for less than 30% of the facial area; moderate: the pigmentation is yellowish brown, accounting for less than 50% of the facial area, or light Brown covers 30-50% of the facial area; severe: dark brown, light brown or yellowish brown spots occupy more than 50% of the facial area), divided into 3 groups on average, the control group is a gel without wormwood brass extract . How to use: After cleaning the face before going to bed, take an appropriate amount of the freckle cream of the present invention and apply it evenly on the face, and gently pat it for absorption; you can use more on the freckles, and gently massage for 3 to 5 minutes to allow the skin to fully absorb it. The time was 1 month, and the results are shown in Table 1.

[0035] Curative effect standard:

[0036] (1) Basic cure: more than 90% of the area of ​​pigment...

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PUM

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Abstract

The invention belongs to the field of cosmetics with special purposes and in particular relates to folium artemisiae argyi flavone freckle-removing gel. The folium artemisiae argyi flavone freckle-removing gel is characterized by being prepared from the following components in parts by weight: 23 percent to 26 percent of folium artemisiae argyi extract, 4.5 percent to 5.5 percent of water-solubleazone, 0.8 percent to 1.2 percent of a gelling agent, 1 percent to 1.5 percent of a humectant, 2 percent to 3 percent of a surfactant, 0.5 percent to 1 percent of a co-surfactant and the balance of purified water which is added until the content is 100 percent. The folium artemisiae argyi flavone freckle-removing gel provided by the invention has the advantages that a production technology of thefolium artemisiae argyi extract is simple, the consumption of organic solvents is less and the variety of flavones in a product is abundant; the content of the flavone in the folium artemisiae argyi extract is detected by adopting an ultraviolet spectrophotometry and is 21.3 percent to 27.5 percent. Folium artemisiae argyi oil has an anti-allergic effect; when the content of the folium artemisiaeargyi oil is relatively low, the anaphylactic reaction probability in a utilization process is easy to reduce; after a transdermal agent azone is added, the folium artemisiae argyi flavone can easilydirectly act on freckles through skin and the metabolism of skin cells is accelerated, so that the effects of realizing freckle fading and preventing new freckles from being generated are realized.

Description

technical field [0001] The invention belongs to the field of special-purpose cosmetics, and in particular relates to a freckle-removing gel with wormwood flavonoids. Background technique [0002] Wormwood, also known as mugwort and mugwort, is a perennial herb of the genus Artemisia in the Asteraceae family. It is a traditional Chinese medicine in my country. Its leaves are used as medicine. Cold to relieve pain, warm the meridian to stop bleeding and other effects. Modern research shows that its main chemical components include volatile oil, eucalyptane, triterpenoids, flavonoids, and many trace elements. [0003] Flavonoids are an effective free radical scavenger and have anti-oxidation effects. At present, there are health foods with flavonoids as functional ingredients on the market, which mainly promote the health care effect of beauty and freckle removal; many plant flavonoid extracts have been developed in China. Reduce pigmentation and moisturize skin, such as ginkg...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/04A61K8/49A61Q19/02A61P37/08
CPCA61K8/046A61K8/4906A61K8/97A61Q19/02
Inventor 马述腾
Owner 马述腾
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