55 results about "Benzyl Compounds" patented technology

The present invention provides a protecting reagent that can be removed in a high yield even under acidic conditions and can afford a resulting product at a high purity in an organic synthesis reaction such as peptide synthesis and the like. The inventive protecting reagent is particular benzylic compound having only one hydroxyl group substituted by an organic group having an aliphatic hydrocarbon group having a carbon number of not less than 14.

Disclosed is a process for the production of a benzaldehyde of the formula (II), which comprises the steps of: mixing a mixed solution (1) or (2) with water and an acid to prepare a mixed reaction solution, where the mixed solution (1) contains a salt produced by reacting a benzyl compound of the formula (I) having a leaving group (L) with hexamethylenetetramine in a solvent and a solvent and the mixed solution (2) contains the compound of the formula (I), a solvent for the compound and hexamethylenetetramine; and subjecting the mixed reaction solution to a reaction to produce the benzaldehyde compound, wherein the molar ratio of hexamethylenetetramine to the compound of the formula (I) is adjusted to a value not smaller than 0.25 and smaller than 1.00. (I) (II) wherein L represents a halogen atom or the like; x, y and z independently represent an integer of 0 or 1, provided that sum total of x, y and z ranges from 1 to 3; R<1> to R<3> independently represent a hydrogen atom or a hydrocarbon group which may have a substituent, or any two members of R1 to R3 may together form an alkylenedioxy group and form a cyclic structure together with two contiguous carbon atoms located on the benzene ring.

The invention discloses a preparation method of a perhydrofluorene or perhydrofluorene alkyl substitute.The preparation method includes following steps: (1), enabling a phenol compound or an aromatic hydrocarbon compound or an arone compound or an aromatic ether compound to be in alkylation reaction with a benzyl compound in the presence of a first catalyst to generate substituted or unsubstituted diphenylmethane, wherein the first catalyst is an acidic catalyst; (2), enabling the substituted or unsubstituted diphenylmethane to be in hydrogenation or hydrogenation and dehydrogenation reaction with hydrogen in the presence of a second catalyst to obtain the perhydrofluorene or perhydrofluorene alkyl substitute, wherein the second catalyst is a mechanical mixture of a metal catalyst and an acid catalyst or the metal catalyst loaded on the acid catalyst.

The invention discloses a method for functionalization modification of benzyl hydrogen of a benzyl-containing compound with C-C double bonds or carbonyl groups. According to the method, the benzyl-containing compound and dimethyl sulfoxide are subjected to a one-pot reaction in the presence of ammonium persulfate and sodium methylate in a protective atmosphere so as to obtain a styrene derivative;or the benzyl-containing compound and dimethyl sulfoxide are subjected to a one-pot reaction in the presence of potassium persulfate and sodium methylate in an air environment so as to obtain a phenyl ketone derivative. The method realizes high-yield high-selectivity modification of benzyl hydrogen of the benzyl-containing compound with C-C double bonds or carbonyl groups under nonmetal catalyticand mild reaction conditions through one-step reaction; and the method is simple in step, short in process flow, low in cost and beneficial for industrial production.

A curable polyvinyl benzyl compound represented by the following general formula (1) wherein R1 represents a C2-20 organic group, R2 represents a hydrogen atom, etc., x is an integer of 0 to 4, and n is an integer of 0 to 2. The compound is obtained by reacting a fluorene compound with a vinylbenzyl halide in the presence of an alkali.

The present invention provides a protecting reagent that can be removed in a high yield even under acidic conditions and can afford a resulting product at a high purity in an organic synthesis reaction such as peptide synthesis and the like. The inventive protecting reagent is particular benzylic compound having only one hydroxyl group substituted by an organic group having an aliphatic hydrocarbon group having a carbon number of not less than 14.

Provided herein are (phenylene)dialkanamines, and methods of producing such (phenylene)dialkanamines from various furanyl and benzyl compounds. Such furanyl compounds may include, for example, bis(nitroalkyl)furans, bis(aminoalkyl)furans, and nitroalkyl(furan)acetonitriles. Such compounds may include, for example, bis(nitroalkyl)benzenes. Provided herein are also alkyldiamines, and methods for producing such alkyldiamines from furanyl compounds.

The invention provides a high-voltage direct-current cable material and a preparation method thereof. The high-voltage direct-current cable material comprises the following components in parts by mass: 90-100 parts of low-density polyethylene, 0.5-3.5 parts of modified nanometer magnesia, 0.1-0.5 part of molten paraffin, 0.001-0.08 part of an antioxidant and 0.001-2.5 parts of a benzyl compound. The preparation method comprises the following steps: preparing the modified nanometer magnesia by using a drum ball-milling method, premixing the raw materials, and finally pelleting, thereby obtaining the high-voltage direct-current cable material. The high-voltage direct-current cable material provided by the scheme of the invention is excellent in space charge accumulation inhibition property under the condition of 40kV / mm and high in breakdown field strength, and the requirement of high-voltage direct-current cable power transmission of 100kV can be met.

Processes for selectively alkylating and / or dealkylating one ring of cyclohexylbenzyl and / or biphenyl compounds are provided. Such selective alkylation and / or dealkylation takes place through a transalkylation reaction between the cyclohexylbenzyl compound and a substituted or unsubstituted benzene, which replaces the phenyl moiety of the cyclohexylbenzyl compound. The transalkylated cyclohexylbenzyl may be dehydrogenated to give a corresponding biphenyl compound. The same reaction steps can be utilized with respect to biphenyl compounds by first partially hydrogenating one phenyl ring of the biphenyl compound, thereby obtaining a corresponding cyclohexylbenzyl compound, which may undergo the transalkylation and, optionally, subsequent dehydrogenation. Combinations of any two or more of partial hydrogenation, transalkylation, and dehydrogenation enable targeted substitution (or de-substitution) of only one ring of cyclohexylbenzyl and / or biphenyl compounds, thereby providing superior control in designing the synthesis of these compounds.

The invention belongs to the field of organic synthesis and relates to a method of reducing carbonyl compound into alcohol in air atmosphere at room temperature. The method includes: firstly, adding methanol, a catalyst and the carbonyl compound into a reaction bottle and slowly adding silane into the reaction bottle, magnetically stirring the components and carrying out a reaction for 10 min to 8hours in air atmosphere at room temperature to obtain a mixture containing a benzyl compound after the reaction is finished; secondly, extracting the mixture containing the benzyl compound with an extraction agent dichloromethane, mixing organic phases, and washing the organic phases with a washing agent deionized water, drying the organic phases with anhydrous sodium sulfate, and evaporating theorganic phases to remove a solvent and obtain a crude product of a benzyl alcohol compound; finally, separating and purifying the crude product through column chromatography to prepare a pure productof the benzyl alcohol compound. In the method, a reducing agent is low in toxicity and is clean and environment-friendly. The method is free of a noble metal catalyst and is low in cost, is gentle inreaction conditions, and can reach high selectivity and yield.

The invention relates to a technical scheme that under the joint action of alkaline and N,N-dimethyl formamide, (E)-(2-(phenylsulfonyl)vinyl)benzene and a derivative thereof are efficiently synthesized from multiple components of benzyl compounds and paraformaldehyde in an environment-friendly mode through a one-pot method without transition metal catalysis. Under the promotion effect of Et3N andN,N-dimethyl formamide, vinyl sulfone and a derivative thereof are generated through intermolecular and intramolecular coupling under a mild condition with phenylbenzyl sulfone and paraformaldehyde asraw materials. Transition metal catalysis and a strong oxidant are not required in the method, and a new path is provided for synthesis of vinyl sulfone compounds. The method further has the characteristics that a reaction system is simple, reaction conditions are mild, the quantity of reaction equipment is small, experiment operation is easy and convenient, and the yield is above-average.

The present invention discloses a process for preparing perhydrofluorene or alkyl-substituted perhydrofluorene, comprising the steps of: (1) reacting a phenolic compound or an aromatic hydrocarbon compound or an aromatic ketone compound or an aromatic ether compound with a benzyl compound to carry out an alkylation reaction in the presence of a first catalyst, thereby to produce substituted or unsubstituted diphenyl methane, wherein the first catalyst is an acidic catalyst; and (2) reacting the substituted or unsubstituted diphenyl methane with hydrogen gas to carry out an hydrogenation reaction or a hydrodeoxygenation reaction, thereby to produce perhydrofluorene or alkyl-substituted perhydrofluorene, wherein the second catalyst is a physical mixture of a metal catalyst and an acidic catalyst or a metal catalyst loaded on an acidic catalyst.