55 results about "Benzyl Compounds" patented technology

The invention provides a high-voltage direct-current cable material and a preparation method thereof. The high-voltage direct-current cable material comprises the following components in parts by mass: 90-100 parts of low-density polyethylene, 0.5-3.5 parts of modified nanometer magnesia, 0.1-0.5 part of molten paraffin, 0.001-0.08 part of an antioxidant and 0.001-2.5 parts of a benzyl compound. The preparation method comprises the following steps: preparing the modified nanometer magnesia by using a drum ball-milling method, premixing the raw materials, and finally pelleting, thereby obtaining the high-voltage direct-current cable material. The high-voltage direct-current cable material provided by the scheme of the invention is excellent in space charge accumulation inhibition property under the condition of 40kV / mm and high in breakdown field strength, and the requirement of high-voltage direct-current cable power transmission of 100kV can be met.

The invention relates to an octahydro cyclopentenopyridine (c) carboxylic acid derivative and a preparing method thereof, providing basis for designing and preparing compounds with different biological activities. A chemical structural formula is shown in the fight formula, wherein, R1 is one of alkoxy, bydroxy and amine. R2 and R3 are one of bydroxy, fluorine and hydrogen. N protecting group is tertbutyloxycarbonyl, benzyloxycarbonyl or benzyl. The compounds are optically pure. Starting from natural methionine ester or hydrochloride thereof, the compound of (S)-2-((benzyloxycarbonyl)(propargyl)-amine)butane-3-carboxylic ester (5) is obtained through substitution, oxidation and elimination. After reactions of cobalt carbonyl catalytic cyclization, and the like, (S)-2-benzyloxycarbonyl-5-octahydro cyclopentenopyridine (c)-1- carboxylic ester is obtained. Series of deritative compounds are obtained through reduction of carbonyl, fluorination, chiral separation, hydrolysis and condensation.

The invention discloses a method for preparing etimicin sulfate, and belongs to the technical field of medicines. The method comprises the steps of: adding copper acetate monohydrate into gentamicin C1a to form a copper ion complex; then adding a benzyl compound into a reaction system, controlling the temperature at 15-40 DEG C, and then adding alkali into the reaction system to react; decoppering and purifying the obtained reaction liquid so as to obtain a light yellow oily compound I; adding acetic acid into the oily substance, controlling the temperature at 5-15 DEG C, adding acetaldehyde to react for a while, adding a catalyst Pd / C and continuously filling hydrogen to react; and separating, purifying and acidizing the reaction liquid so as to obtain etimicin sulfate. The method of utilizing benzyl to protect amino groups is adopted, and high selectivity is obtained; and two reaction steps of reduction and deprotection are completed through a 'one-pot method', and the method is low in reaction temperature and takes a short period, thus, side reaction is less, purification is easy, the reaction and separation costs are lowered, and the method can be easily applied to industrial production.

The present invention provides a protecting reagent that can be removed in a high yield even under acidic conditions and can afford a resulting product at a high purity in an organic synthesis reaction such as peptide synthesis and the like. The inventive protecting reagent is particular benzylic compound having only one hydroxyl group substituted by an organic group having an aliphatic hydrocarbon group having a carbon number of not less than 14.

A curable polyvinyl benzyl compound represented by the following general formula (1): wherein R1 represents a C2-20 organic group, R2 represents a hydrogen atom, etc., x is an integer of 0 to 4, and n is an integer of 0 to 2. The compound is obtained by reacting a fluorene compound with a vinylbenzyl halide in the presence of an alkali.

The invention discloses an application of a metallide / palladium compound catalytic reduction system in debenzylation reaction and deuterization reaction of benzyl-containing compounds. The reaction comprises the following steps: under the protection of nitrogen, suspending a palladium compound and a metallide in a solvent, stirring for 5 minutes, adding the benzyl-containing compounds, carrying out a reaction for 0.5 to 48 h at the temperature of -30 DEG C to 150 DEG C, adding ice water to stop the reaction, adjusting the pH value to 3.5 with diluted hydrochloric acid, extracting the reactionsolution by a solvent, drying by distillation, purifying by column chromatography, and thus completing the reaction.

Disclosed is a process for the production of a benzaldehyde of the formula (II), which comprises the steps of: mixing a mixed solution (1) or (2) with water and an acid to prepare a mixed reaction solution, where the mixed solution (1) contains a salt produced by reacting a benzyl compound of the formula (I) having a leaving group (L) with hexamethylenetetramine in a solvent and a solvent and the mixed solution (2) contains the compound of the formula (I), a solvent for the compound and hexamethylenetetramine; and subjecting the mixed reaction solution to a reaction to produce the benzaldehyde compound, wherein the molar ratio of hexamethylenetetramine to the compound of the formula (I) is adjusted to a value not smaller than 0.25 and smaller than 1.00. (I) (II) wherein L represents a halogen atom or the like; x, y and z independently represent an integer of 0 or 1, provided that sum total of x, y and z ranges from 1 to 3; R<1> to R<3> independently represent a hydrogen atom or a hydrocarbon group which may have a substituent, or any two members of R1 to R3 may together form an alkylenedioxy group and form a cyclic structure together with two contiguous carbon atoms located on the benzene ring.

Electroplating methods enable the plating of photoresist defined features which have substantially uniform morphology. The electroplating methods include copper electroplating baths with reaction products of imidazole compounds, bisepoxides and halobenzyl compounds to electroplate the photoresist defined features. Such features include pillars, bond pads and line space features.

The invention is a phosphate-free and low sodium boiler water treatment medicament. The medicament comprises the following ingredients: poly-alkyl acrylate; polymaleic acid salt; poly epoxy butanedioic acid; benzyl compound; sodium salt; and water. This is a multifunctional phosphate-free boiler inside treatment agent containing all-organic polymers, powerful dispersants and auxiliaries and other compositions. Through the reaction steps of chelation, dispersion of the hard scale in boiler water, fouling prevention, prevention of potential corrosion caused by the total deposition of iron and copper and the like in a boiler tube compartment, the PH value of the boiler water is stablized, meanwhile the incurrence of corrosion problems in pipelines and valves is reduced, the treatment medicament can help to replace completely the use of sodium phosphate tribasic, to prevent entrainment and improve the steam quality. The critical salt content in the boiler is increased, the concentration of boiler water is facilitated and energy is saved.

The invention discloses a method for functionalization modification of benzyl hydrogen of a benzyl-containing compound with C-C double bonds or carbonyl groups. According to the method, the benzyl-containing compound and dimethyl sulfoxide are subjected to a one-pot reaction in the presence of ammonium persulfate and sodium methylate in a protective atmosphere so as to obtain a styrene derivative;or the benzyl-containing compound and dimethyl sulfoxide are subjected to a one-pot reaction in the presence of potassium persulfate and sodium methylate in an air environment so as to obtain a phenyl ketone derivative. The method realizes high-yield high-selectivity modification of benzyl hydrogen of the benzyl-containing compound with C-C double bonds or carbonyl groups under nonmetal catalyticand mild reaction conditions through one-step reaction; and the method is simple in step, short in process flow, low in cost and beneficial for industrial production.

A process for producing an aromatic aldehyde compound represented by a general formula (3): (wherein R′ and n are as defined below), which comprises reacting a benzyl compound represented by a general formula (1): (wherein R may represents hydrogen atom, n represents an integer of 1 to 6, and R′ may be the same or different and represent a hydrogen atom or an alkyl gorup, an alkyl group or a phenyl group which may have a substituent) with an oxy-compound of bromine represented by the formula (2): MBrOm  (2) (wherein M represents a hydrogen atom or a metal atom, and m represents an integer of 1 to 3) in the presence of an acid catalyst. According to this method, an aromatic aldehyde compound can be produced in high selectivity by a simple operation without using an expensive catalyst or transition metal.

A curable polyvinyl benzyl compound represented by the following general formula (1) wherein R1 represents a C2-20 organic group, R2 represents a hydrogen atom, etc., x is an integer of 0 to 4, and n is an integer of 0 to 2. The compound is obtained by reacting a fluorene compound with a vinylbenzyl halide in the presence of an alkali.

The present invention provides a protecting reagent that can be removed in a high yield even under acidic conditions and can afford a resulting product at a high purity in an organic synthesis reaction such as peptide synthesis and the like. The inventive protecting reagent is particular benzylic compound having only one hydroxyl group substituted by an organic group having an aliphatic hydrocarbon group having a carbon number of not less than 14.

The invention discloses a method for preparing PINO (phthimide-n-oxyl) derivatives through directly coupling NHPI (n-hydroxyphthalimide) and benzyl-containing compounds under non-metal catalysis. According to the method, under the nitrogen protection, the benzyl-containing compounds, N-hydroxyphthalimide and K2S2O8 take a one-pot reaction under the catalysis of tetraalkyl ammonium salts to produce PINO derivatives. By using the method, the next step of reaction is performed under the mild condition; the PINO derivatives are synthesized at a high yield; in addition, the cost is low; the operation is simple; the industrial protection requirements are met.

The invention discloses a pesticide for a forest farm. The pesticide is formed by a main agent and an auxiliary agent, wherein the main agent contains the following components in percent by weight: 1.8-20.0wt% of acetamiprid and 12.6-40.0wt% of acephate; the auxiliary agent contains the following components in percent by weight: 25.0-45.0wt% of methanol, 1.0-16.0wt% of benzyl compound-phenol polyoxyethylene ether, 1.0-10.0wt% of tween-80, 0.1-5.0wt% of cyclohexanone, 0.1-2.0wt% of pyrogallic acid and 0.5-2.0wt% of propylgallate, wherein the mass percents of all the substances are calculated bytotal mass of the pesticide. The pesticide disclosed by the invention has the advantages that the acetamiprid and the acephate are mixed according to proper proportion, the proper auxiliary agent isadded as an additive and the pesticides in the forms of emulsion oil, microemulsion agents and aqueous emulsion agents can be prepared by common methods; and the pesticide has the characteristics of good insect-removing effect, lasting pesticide effect and less hazard to human and other animals.

The invention discloses a synthesis method of aromatic benzyl ketone, which comprises the following step: by using oxygen and / or air as an oxidant, oxidizing an aromatic benzyl compound shown in a formula (I) under the action of a catalytic system to obtain aromatic benzyl ketone shown in a formula (II). The catalytic system is formed by combining ferric ions, nitrate radicals and N-hydroxyimide derivatives and does not contain heavy metal ions harmful to human bodies, wherein the molar ratio of the ferric ions to the nitrate radicals is 1: (0.5-5), and the molar ratio of the ferric ions to the N-hydroxyimide derivatives is (0.01-0.1): (0.03-0.2). The method disclosed by the invention is wide in substrate applicability and high in atom utilization rate, avoids the use of harmful heavy metals such as copper and cobalt, and has the characteristics of high efficiency, economy and environmental protection. The formulas are as follows: Ar-CH2-R (I) and Ar-CO-R (II).

The invention relates to the technical field of asphalt regeneration, in particular to an asphalt thermal regeneration production process. The asphalt thermal regeneration production process can improve compatibility of asphaltenes and improve stability of performance of old asphalt after thermal regeneration. The asphalt thermal regeneration production process is characterized in that a benzyl compound is added to melted old asphalt; the benzyl compound contains a large amount of active hydrogen, and is grafted onto a high or low molecular compound by the active hydrogen, so that a 'bridge' is set up between the asphaltenes with different molecular weights and molecular structures to improve the compatibility of the asphaltenes and improve the stability of the performance of the old asphalt after thermal regeneration.

The invention discloses a catalyst for catalyzing oxidation of a benzyl compound to prepare a carbonyl compound and a preparation method and application of the catalyst and belongs to the technical field of catalysts. The catalyst comprises an active component of cobalt tetroxide, a single metal oxide of copper oxide or a composite oxide of the cobalt tetroxide and the copper oxide. According to the preparation method, a silicon-based mesoporous molecular sieve hard template agent is used, a metal oxide is filled into pores of a molecular sieve, and the hard template agent is removed at a lowtemperature, so that a metal oxide with a large specific surface area is prepared. Compared with metal oxides prepared by using a coprecipitation method, a sol-gel method and the like, the metal oxideprepared by using the method has a remarkably increased specific surface area. The prepared metal oxide with the large specific surface area can be applied to a liquid-phase oxidation reaction of thebenzyl compound at a low temperature. The catalyst has the advantages of being low in cost, high in benzyl compound conversion rate, high in selectivity of corresponding carbonyl compounds, mild in reaction condition, good in stability and easy to separate.

Provided herein are (phenylene)dialkanamines, and methods of producing such (phenylene)dialkanamines from various furanyl and benzyl compounds. Such furanyl compounds may include, for example, bis(nitroalkyl)furans, bis(aminoalkyl)furans, and nitroalkyl(furan)acetonitriles. Such compounds may include, for example, bis(nitroalkyl)benzenes. Provided herein are also alkyldiamines, and methods for producing such alkyldiamines from furanyl compounds.

The invention provides a high-voltage direct-current cable material and a preparation method thereof. The high-voltage direct-current cable material comprises the following components in parts by mass: 90-100 parts of low-density polyethylene, 0.5-3.5 parts of modified nanometer magnesia, 0.1-0.5 part of molten paraffin, 0.001-0.08 part of an antioxidant and 0.001-2.5 parts of a benzyl compound. The preparation method comprises the following steps: preparing the modified nanometer magnesia by using a drum ball-milling method, premixing the raw materials, and finally pelleting, thereby obtaining the high-voltage direct-current cable material. The high-voltage direct-current cable material provided by the scheme of the invention is excellent in space charge accumulation inhibition property under the condition of 40kV / mm and high in breakdown field strength, and the requirement of high-voltage direct-current cable power transmission of 100kV can be met.

Provided are a curable resin composition, a prepreg, a cured product, a laminate, and a build-up film which exhibit halogen-free flame retardancy despite being high in heat resistance and low in dielectric loss tangent. The curable resin composition contains: component (A): a radically polymerizable resin which has a plurality of reactive unsaturated groups in the molecule and in which the functional group concentration of the unsaturated groups is 0.0010 mol / g to 0.0070 mol / g; component (B): a vinyl benzyl compound having a reactive functional group concentration of 0.0020 mol / g-0. 0050 mol / g; and component (C): an initiator. The curable resin composition is characterized in that the phosphorus content in the component (B) is 1.0%-4.5% relative to the total of the component (A) and the component B.

The invention discloses an acrylic fiber leveling agent which comprises the following components in percentage by mass: 1.0%-2.0% of an emulsifier, 3.0%-5.0% of fatty amine and derivatives thereof, 1.0%-3.0% of fatty alcohols, 5.0%-36.0% of pyridine and derivatives thereof, 8.0%-48.0% of a benzyl compound and 6.0%-82.0% of water. The acrylic fiber leveling agent adopting the above-mentioned components has good diffusivity and mobility, so that dye molecules are uniformly combined with fiber molecules during dyeing, the color difference is reduced, the dyeing glossiness and color fastness are ensured, and the environmental protection requirement is met.

The invention discloses a preparation method of an organochlorine transfer agent benzyl compound, a chlorine transfer agent is prepared by reacting benzyl chloride and hydroxide under a certain condition, the content of chlorine in the prepared phase transfer agent is extremely low through detection, and the industrial application requirement is completely met. The invention also discloses a using method of the chlorine transfer agent. In the process of removing organochlorine from crude oil by using a nucleophilic reagent, the organochlorine transfer agent is added, so that the organochlorine can be in full contact with the nucleophilic reagent, the dechlorination efficiency is remarkably improved, the content of the organochlorine in the crude oil can be effectively reduced, and the harm caused by the organochlorine is greatly reduced.

The invention belongs to the pharmaceutical manufacturing field, which relates to a novel process for the preparation of substituted phenylacetic acids derivatives, especially relates to the preparation of 2-(4-(2-oxocyclopentyl)phenyl)propanoic acid. The process for the preparation of the precursor form of loxoprofen which use 1,4-di-halobenzyl compounds or disubstituted benzyl compounds as starting material, is through the substitution reaction of cyclopentanone groups or its precursor compounds.Wherein X is halogen, L1 is a suitable leaving group selected from halogen, OH, OMs, OTs, OTf and the like; L2 is a suitable leaving group selected from halogen, CN, OH, —CH2OH, —CHO, CH3NO2, ester group, —NR4R5, OTf, OTs, OMs, —C═CR6, —C≡CR7 and the like, wherein R4, R5, R6, R7 are short chain alkyl groups; Z is cyclopentanone group and its precursor form selected fromand the like; R3 is short chain alkyl groups. L3 is a suitable leaving group selected from halogen, OH, OMs, OTs, OTf and the like, or organometallic groups. The invention also include the detailed procedure to convert the precursor compounds of cyclopentanone group to cyclopentanone, followed by the transformation of the precursor compounds of loxoprofen to loxoprofen.

The invention relates to a technical scheme that under the joint action of alkaline and N,N-dimethyl formamide, (E)-(2-(phenylsulfonyl)vinyl)benzene and a derivative thereof are efficiently synthesized from multiple components of benzyl compounds and paraformaldehyde in an environment-friendly mode through a one-pot method without transition metal catalysis. Under the promotion effect of Et3N andN,N-dimethyl formamide, vinyl sulfone and a derivative thereof are generated through intermolecular and intramolecular coupling under a mild condition with phenylbenzyl sulfone and paraformaldehyde asraw materials. Transition metal catalysis and a strong oxidant are not required in the method, and a new path is provided for synthesis of vinyl sulfone compounds. The method further has the characteristics that a reaction system is simple, reaction conditions are mild, the quantity of reaction equipment is small, experiment operation is easy and convenient, and the yield is above-average.

Processes for selectively alkylating and / or dealkylating one ring of cyclohexylbenzyl and / or biphenyl compounds are provided. Such selective alkylation and / or dealkylation takes place through a transalkylation reaction between the cyclohexylbenzyl compound and a substituted or unsubstituted benzene, which replaces the phenyl moiety of the cyclohexylbenzyl compound. The transalkylated cyclohexylbenzyl may be dehydrogenated to give a corresponding biphenyl compound. The same reaction steps can be utilized with respect to biphenyl compounds by first partially hydrogenating one phenyl ring of the biphenyl compound, thereby obtaining a corresponding cyclohexylbenzyl compound, which may undergo the transalkylation and, optionally, subsequent dehydrogenation. Combinations of any two or more of partial hydrogenation, transalkylation, and dehydrogenation enable targeted substitution (or de-substitution) of only one ring of cyclohexylbenzyl and / or biphenyl compounds, thereby providing superior control in designing the synthesis of these compounds.

The invention belongs to the field of organic synthesis and relates to a method of reducing carbonyl compound into alcohol in air atmosphere at room temperature. The method includes: firstly, adding methanol, a catalyst and the carbonyl compound into a reaction bottle and slowly adding silane into the reaction bottle, magnetically stirring the components and carrying out a reaction for 10 min to 8hours in air atmosphere at room temperature to obtain a mixture containing a benzyl compound after the reaction is finished; secondly, extracting the mixture containing the benzyl compound with an extraction agent dichloromethane, mixing organic phases, and washing the organic phases with a washing agent deionized water, drying the organic phases with anhydrous sodium sulfate, and evaporating theorganic phases to remove a solvent and obtain a crude product of a benzyl alcohol compound; finally, separating and purifying the crude product through column chromatography to prepare a pure productof the benzyl alcohol compound. In the method, a reducing agent is low in toxicity and is clean and environment-friendly. The method is free of a noble metal catalyst and is low in cost, is gentle inreaction conditions, and can reach high selectivity and yield.

The present invention discloses a process for preparing perhydrofluorene or alkyl-substituted perhydrofluorene, comprising the steps of: (1) reacting a phenolic compound or an aromatic hydrocarbon compound or an aromatic ketone compound or an aromatic ether compound with a benzyl compound to carry out an alkylation reaction in the presence of a first catalyst, thereby to produce substituted or unsubstituted diphenyl methane, wherein the first catalyst is an acidic catalyst; and (2) reacting the substituted or unsubstituted diphenyl methane with hydrogen gas to carry out an hydrogenation reaction or a hydrodeoxygenation reaction, thereby to produce perhydrofluorene or alkyl-substituted perhydrofluorene, wherein the second catalyst is a physical mixture of a metal catalyst and an acidic catalyst or a metal catalyst loaded on an acidic catalyst.