92results about "Reciprocating system" patented technology

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

A fluid management system may include a fluid pump capable of generating a pulsatile flow of fluid, a fluid pathway for transporting the pulsatile flow of fluid from a fluid source through the fluid pump to a medical device, a dampening element in fluid communication with the fluid pathway and operably independent of the fluid pump, the dampening element comprising one or more barrels, each barrel including a movable seal member disposed within the barrel and a biasing member disposed within the barrel and engaged with the movable seal member, the dampening element being responsive to pressure fluctuations of the pulsatile fluid flow to actively dampen the pressure fluctuations, and a fluid flow sensor disposed along the fluid pathway between the dampening element and the medical device to measure a flow rate of the smoothened pulsatile fluid flow in both flow directions.

The invention provides a single-needle hemodialysis blood pipeline device which comprises a piston type container, a liftable piston plate is connected to the interior of the piston type container through a first elastic piece, an artery pot and a vein pot are arranged on one side of the piston type container and communicate with each other through a three-way pipeline, one end of the first pipeline communicates with the artery pot through a first valve, and the other end of the first pipeline communicates with the vein pot through a second valve. The blood pump is communicated with a dialyzer, one end of the dialyzer is communicated with a pipeline II, and the pipeline II is communicated with the vein pot through a valve II; the pipeline III is communicated with the pipeline I and the piston type container and is provided with a valve III; the fourth pipeline is communicated with the second pipeline and the piston type container and provided with a fourth valve, and the piston type container is further provided with a switching mechanism. According to the device, blood can be fully dialyzed only through single-needle puncture, it is ensured that the blood in the dialyzer makes full contact with the dialyzer, the toxin removing efficiency is improved, and finally full dialysis in a special scene is achieved.

A method and device are provided for centrifugally separating plasma from whole blood in which whole blood is introduced into a flow circuit having a blood access device connected to a first tubing for drawing whole blood from a blood source and for flowing whole blood to a centrifugal separation chamber; a volume of saline is added to the whole blood as it flows through the first tubing to dilute the whole blood; the volume of saline added to the whole blood is tracked; the whole blood having saline added thereto is separated in the centrifugal separation chamber so that an interface is created between the plasma and added saline and the cellular components of the whole blood; the separated plasma and added saline is flowed from the centrifugal separation chamber to a collection container; and a volume for the plasma and added saline in the collection container is determined.

The disclosure relates to systems, devices, and methods for sensing the volume of liquid in a container, such as within a medical device. The systems, devices, and methods can measure the properties of a signal sent across a container using non-intrusive components that remain outside the container. The measured properties can be used to determine the volume of liquid in the container, as well as changes to the volume of liquid representing flow into and out of the container.

A fluid management system may include a fluid pump capable of generating a pulsatile flow of fluid, a fluid pathway for transporting the pulsatile flow of fluid from a fluid source through the fluid pump to a medical device, a dampening element in fluid communication with the fluid pathway and operably independent of the fluid pump, the dampening element comprising one or more barrels, each barrel including a movable seal member disposed within the barrel and a biasing member disposed within the barrel and engaged with the movable seal member, the dampening element being responsive to pressure fluctuations of the pulsatile fluid flow to actively dampen the pressure fluctuations, and a fluid flow sensor disposed along the fluid pathway between the dampening element and the medical device to measure a flow rate of the smoothened pulsatile fluid flow in both flow directions.

An extracorporeal and drug delivery system includes (i) a renal failure therapy machine operable with a blood filter in fluid communication with an arterial line and a venous line, the machine including (a) an effluent pump for pumping effluent from the blood filter at an effluent flowrate, and at least one of (b) a dialysis fluid pump for pumping dialysis fluid to the blood filter at a dialysis fluid flowrate, (c) a predilution pump for pumping replacement fluid into the arterial line at a predilution flowrate, or (d) a postdilution pump for pumping replacement fluid into the venous line at a postdilution flowrate; (ii) an infusion pump operable to deliver an intravenous (“IV”) drug to the patient at an IV drug flowrate; and (iii) a coordinating logic implementor configured to adjust the IV drug flowrate based on an amount of the IV drug removed via the effluent flowrate.

The present invention relates to a disposable which has a fluid line (4002) and a connector (4001) for fluidically connecting the fluid line (4002), for example to a first lumen (31) of a first fluid guide (3) of a port (100) of a medical treatment device (2000), wherein the connector (4001) has a connector lumen (4004) which is at least partially surrounded or formed by a wall (4021), and has a contact protection casing (4017) which has a connection opening (4019). The connector lumen (4004) opens into or ends in an opening (4023) in the interior of the contact protection casing (4017). The connector (4001) also has a contact protection sleeve (4031) which is arranged within the contact protection casing (4017) so as to be movable along the wall (4021) of the connector lumen (4004) or relative to the wall (4021).

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

An extracorporeal and drug delivery system includes a renal failure therapy machine operable with a blood filter in fluid communication with an arterial line and a venous line, the machine including an effluent pump for pumping effluent from the blood filter, and at least one of a dialysis fluid pump for pumping dialysis fluid to the blood filter at a dialysis fluid flowrate, a predilution pump for pumping replacement fluid into the arterial line at a predilution flowrate, or a postdilution pump for pumping replacement fluid into the venous line at a postdilution flowrate; an infusion pump operable to deliver an intravenous (“IV”) drug to the patient; and a coordinating logic implementor configured to determine if a formulation adjustment should be made to the IV drug when a constituent of the IV drug exists in the dialysis fluid, the predilution replacement fluid, and / or the postdilution replacement fluid.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

The present disclosure provides methods and systems for improving extracorporeal blood processing and therapy.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

To provide a method and a system capable of performing a blood collection process more efficiently for a donor at a higher speed.SOLUTION: Disclosed is an embodiment including a device for separating a component from blood. The embodiment includes separation of blood plasma from whole blood. Also disclosed is an embodiment including a method and a device for positioning a part of a disposable article, for example, a loop 520, in a medical device. The embodiment includes use of a surface for automatically guiding loops and positioning the loops to predetermined positions.SELECTED DRAWING: Figure 4A

To control pressure fluctuation in an extracorporeal circulation part while reducing an extracorporeal circulation blood amount.SOLUTION: An arterial clamp capable of opening and closing the arterial blood circuit, a venous clamp capable of opening and closing the venous blood circuit, a pump capable of introducing or discharging air into or from the gas circuit, and a processing unit configured to control the pump, the arterial clamp, and the venous clamp, and a clamp control unit configured to perform control such that the flow path of the arterial blood circuit is opened by the arterial clamp and the flow path of the venous blood circuit is closed by the venous clamp during the blood removal treatment, and the flow path of the arterial blood circuit is closed by the arterial clamp and the flow path of the venous blood circuit is opened by the venous clamp during the blood returning treatment.SELECTED DRAWING: Figure 3

A flow path (42) is formed in a cassette body (40) of a blood component collection cassette (28). The cassette body (40) includes a bulging structure (50) in which at least a portion of the flow path is formed. A first gripped member (60), which is configured to be gripped by a first gripping member (78) provided on a centrifugal separation device (14), is disposed on one surface of the bulging structure (50) in a thickness direction thereof. A second gripped member (62), which is configured to be gripped by a second gripping member (80) to which a load detection unit (82) that is provided on the centrifugal separation device (14) is fixed, is disposed on another surface of the bulging structure (50) in the thickness direction thereof.

To provide a blood purification device capable of preventing connection of a chamber member from being forgotten when switching a needle state to a single needle state for executing blood purification treatment.SOLUTION: A blood purification device capable of arbitrarily switching a needle state between a double need state and a single needle state includes: a blood pump 4; a fed liquid amount detection part 11 for detecting a fed liquid amount of liquid by the drive of the blood pump 4; a pressure detection part 6 for detecting the pressure in a blood circuit; a chamber member 9 connected to an air trap chamber 5 in the single needle state for causing blood in the blood circuit to flow in and pooling the blood in a blood collection phase for collecting blood from a patient, and for causing the pooled blood to outflow to the blood circuit and returning the blood in a blood returning phase for returning the blood to the patient; and a connection determination part 12 for determining presence or absence of the connection of the chamber member 9 on the basis of the fed liquid amount detected by the fed liquid amount detection part 11 and the pressure detected by the pressure detection part 6.SELECTED DRAWING: Figure 2

The present invention relates to a method for temporarily interrupting an extracorporeal treatment of blood of a patient by use of a blood treatment apparatus. The method comprises activating or controlling a control device provided and configured to bring the blood treatment apparatus into a state in which the blood treatment session of the patient can be interrupted with the intention to continue the blood treatment session. The present invention further relates to a control device, a blood treatment apparatus, a digital storage means, a computer program product as well as a computer program.

A blood component collection system (10) includes a first internal pressure calculation unit (110) adapted to calculate a first internal pressure of a first pressed portion (60) using first calibration curve data (118), a second internal pressure calculation unit (112) adapted to calculate a second internal pressure of a second pressed portion (62) using second calibration curve data (120), and a correction unit (114) adapted to correct the first calibration curve data (118) in a manner so that the first internal pressure becomes equal to the second internal pressure in a state in which operation of a collection and returning pump (100) is stopped during at least one of a collection operation and a returning operation of a first cycle.

An irradiation device includes a processing container including a first chamber, a second chamber and at least one narrow passage in fluid communication at a first end with the first chamber and at a second end with the second chamber, and a rotatable table on which the processing container is mounted, the table having a first state wherein the first chamber is disposed at a higher elevation than the second chamber, and a second state wherein the second chamber is disposed at a higher elevation than the first chamber. The irradiation device also includes ultraviolet (UV) light source disposed proximate to the narrow passage and configured to irradiate fluid passing through the narrow passage.

A fluid management system may include a fluid pump capable of generating a pulsatile flow of fluid, a fluid pathway for transporting the pulsatile flow of fluid from a fluid source through the fluid pump to a medical device, a dampening element in fluid communication with the fluid pathway and operably independent of the fluid pump, the dampening element comprising one or more barrels, each barrel including a movable seal member disposed within the barrel and a biasing member disposed within the barrel and engaged with the movable seal member, the dampening element being responsive to pressure fluctuations of the pulsatile fluid flow to actively dampen the pressure fluctuations, and a fluid flow sensor disposed along the fluid pathway between the dampening element and the medical device to measure a flow rate of the smoothened pulsatile fluid flow in both flow directions.

A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.

Provided is a blood component collection cassette capable of measuring a circuit internal pressure using a simple and economical configuration. A blood component collection cassette (28) includes an inflow line for sending blood or a blood component collected from a donor to a centrifugal separator (14), a return line for returning a predetermined blood component to the donor, and a line forming member forming one of the inflow line and the return line and having a load detection soft portion made of a soft material.

Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.

Provided is a blood component collection cassette, a blood component collection kit, a blood component collection system, and a flow path internal pressure detection method capable of accurately measuring a circuit internal pressure in negative pressure and positive pressure regions. A flow path (42) formed in a cassette body (40) of a blood component collection cassette (28) has a first line (42a) through which blood flows when a blood component separation device is in operation, and a second line (42b) through which blood does not flow when the blood component separation device is in operation. A first line forming member (54) is provided with a first pressure-receiving portion (60) pressed by a first load detector (88) attached to the blood component separation device. A second line forming member (56) is provided with a second pressure-receiving portion (62) pressed by a second load detector (90) attached to the blood component separation device.