69results about "Reciprocating system" patented technology

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

The invention provides a single-needle hemodialysis blood pipeline device which comprises a piston type container, a liftable piston plate is connected to the interior of the piston type container through a first elastic piece, an artery pot and a vein pot are arranged on one side of the piston type container and communicate with each other through a three-way pipeline, one end of the first pipeline communicates with the artery pot through a first valve, and the other end of the first pipeline communicates with the vein pot through a second valve. The blood pump is communicated with a dialyzer, one end of the dialyzer is communicated with a pipeline II, and the pipeline II is communicated with the vein pot through a valve II; the pipeline III is communicated with the pipeline I and the piston type container and is provided with a valve III; the fourth pipeline is communicated with the second pipeline and the piston type container and provided with a fourth valve, and the piston type container is further provided with a switching mechanism. According to the device, blood can be fully dialyzed only through single-needle puncture, it is ensured that the blood in the dialyzer makes full contact with the dialyzer, the toxin removing efficiency is improved, and finally full dialysis in a special scene is achieved.

A method and device are provided for centrifugally separating plasma from whole blood in which whole blood is introduced into a flow circuit having a blood access device connected to a first tubing for drawing whole blood from a blood source and for flowing whole blood to a centrifugal separation chamber; a volume of saline is added to the whole blood as it flows through the first tubing to dilute the whole blood; the volume of saline added to the whole blood is tracked; the whole blood having saline added thereto is separated in the centrifugal separation chamber so that an interface is created between the plasma and added saline and the cellular components of the whole blood; the separated plasma and added saline is flowed from the centrifugal separation chamber to a collection container; and a volume for the plasma and added saline in the collection container is determined.

A fluid management system may include a fluid pump capable of generating a pulsatile flow of fluid, a fluid pathway for transporting the pulsatile flow of fluid from a fluid source through the fluid pump to a medical device, a dampening element in fluid communication with the fluid pathway and operably independent of the fluid pump, the dampening element comprising one or more barrels, each barrel including a movable seal member disposed within the barrel and a biasing member disposed within the barrel and engaged with the movable seal member, the dampening element being responsive to pressure fluctuations of the pulsatile fluid flow to actively dampen the pressure fluctuations, and a fluid flow sensor disposed along the fluid pathway between the dampening element and the medical device to measure a flow rate of the smoothened pulsatile fluid flow in both flow directions.

An extracorporeal and drug delivery system includes (i) a renal failure therapy machine operable with a blood filter in fluid communication with an arterial line and a venous line, the machine including (a) an effluent pump for pumping effluent from the blood filter at an effluent flowrate, and at least one of (b) a dialysis fluid pump for pumping dialysis fluid to the blood filter at a dialysis fluid flowrate, (c) a predilution pump for pumping replacement fluid into the arterial line at a predilution flowrate, or (d) a postdilution pump for pumping replacement fluid into the venous line at a postdilution flowrate; (ii) an infusion pump operable to deliver an intravenous (“IV”) drug to the patient at an IV drug flowrate; and (iii) a coordinating logic implementor configured to adjust the IV drug flowrate based on an amount of the IV drug removed via the effluent flowrate.

The present invention relates to a disposable which has a fluid line (4002) and a connector (4001) for fluidically connecting the fluid line (4002), for example to a first lumen (31) of a first fluid guide (3) of a port (100) of a medical treatment device (2000), wherein the connector (4001) has a connector lumen (4004) which is at least partially surrounded or formed by a wall (4021), and has a contact protection casing (4017) which has a connection opening (4019). The connector lumen (4004) opens into or ends in an opening (4023) in the interior of the contact protection casing (4017). The connector (4001) also has a contact protection sleeve (4031) which is arranged within the contact protection casing (4017) so as to be movable along the wall (4021) of the connector lumen (4004) or relative to the wall (4021).

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

An extracorporeal and drug delivery system includes a renal failure therapy machine operable with a blood filter in fluid communication with an arterial line and a venous line, the machine including an effluent pump for pumping effluent from the blood filter, and at least one of a dialysis fluid pump for pumping dialysis fluid to the blood filter at a dialysis fluid flowrate, a predilution pump for pumping replacement fluid into the arterial line at a predilution flowrate, or a postdilution pump for pumping replacement fluid into the venous line at a postdilution flowrate; an infusion pump operable to deliver an intravenous (“IV”) drug to the patient; and a coordinating logic implementor configured to determine if a formulation adjustment should be made to the IV drug when a constituent of the IV drug exists in the dialysis fluid, the predilution replacement fluid, and / or the postdilution replacement fluid.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

The present disclosure provides methods and systems for improving extracorporeal blood processing and therapy.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

To control pressure fluctuation in an extracorporeal circulation part while reducing an extracorporeal circulation blood amount.SOLUTION: An arterial clamp capable of opening and closing the arterial blood circuit, a venous clamp capable of opening and closing the venous blood circuit, a pump capable of introducing or discharging air into or from the gas circuit, and a processing unit configured to control the pump, the arterial clamp, and the venous clamp, and a clamp control unit configured to perform control such that the flow path of the arterial blood circuit is opened by the arterial clamp and the flow path of the venous blood circuit is closed by the venous clamp during the blood removal treatment, and the flow path of the arterial blood circuit is closed by the arterial clamp and the flow path of the venous blood circuit is opened by the venous clamp during the blood returning treatment.SELECTED DRAWING: Figure 3

A flow path (42) is formed in a cassette body (40) of a blood component collection cassette (28). The cassette body (40) includes a bulging structure (50) in which at least a portion of the flow path is formed. A first gripped member (60), which is configured to be gripped by a first gripping member (78) provided on a centrifugal separation device (14), is disposed on one surface of the bulging structure (50) in a thickness direction thereof. A second gripped member (62), which is configured to be gripped by a second gripping member (80) to which a load detection unit (82) that is provided on the centrifugal separation device (14) is fixed, is disposed on another surface of the bulging structure (50) in the thickness direction thereof.

The present invention relates to a method for temporarily interrupting an extracorporeal treatment of blood of a patient by use of a blood treatment apparatus. The method comprises activating or controlling a control device provided and configured to bring the blood treatment apparatus into a state in which the blood treatment session of the patient can be interrupted with the intention to continue the blood treatment session. The present invention further relates to a control device, a blood treatment apparatus, a digital storage means, a computer program product as well as a computer program.

A blood component collection system (10) includes a first internal pressure calculation unit (110) adapted to calculate a first internal pressure of a first pressed portion (60) using first calibration curve data (118), a second internal pressure calculation unit (112) adapted to calculate a second internal pressure of a second pressed portion (62) using second calibration curve data (120), and a correction unit (114) adapted to correct the first calibration curve data (118) in a manner so that the first internal pressure becomes equal to the second internal pressure in a state in which operation of a collection and returning pump (100) is stopped during at least one of a collection operation and a returning operation of a first cycle.

A fluid management system may include a fluid pump capable of generating a pulsatile flow of fluid, a fluid pathway for transporting the pulsatile flow of fluid from a fluid source through the fluid pump to a medical device, a dampening element in fluid communication with the fluid pathway and operably independent of the fluid pump, the dampening element comprising one or more barrels, each barrel including a movable seal member disposed within the barrel and a biasing member disposed within the barrel and engaged with the movable seal member, the dampening element being responsive to pressure fluctuations of the pulsatile fluid flow to actively dampen the pressure fluctuations, and a fluid flow sensor disposed along the fluid pathway between the dampening element and the medical device to measure a flow rate of the smoothened pulsatile fluid flow in both flow directions.

A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.

Provided is a blood component collection cassette capable of measuring a circuit internal pressure using a simple and economical configuration. A blood component collection cassette (28) includes an inflow line for sending blood or a blood component collected from a donor to a centrifugal separator (14), a return line for returning a predetermined blood component to the donor, and a line forming member forming one of the inflow line and the return line and having a load detection soft portion made of a soft material.

Provided is a blood component collection cassette, a blood component collection kit, a blood component collection system, and a flow path internal pressure detection method capable of accurately measuring a circuit internal pressure in negative pressure and positive pressure regions. A flow path (42) formed in a cassette body (40) of a blood component collection cassette (28) has a first line (42a) through which blood flows when a blood component separation device is in operation, and a second line (42b) through which blood does not flow when the blood component separation device is in operation. A first line forming member (54) is provided with a first pressure-receiving portion (60) pressed by a first load detector (88) attached to the blood component separation device. A second line forming member (56) is provided with a second pressure-receiving portion (62) pressed by a second load detector (90) attached to the blood component separation device.

To enable detection of blood clots in an extracorporeal blood circulation, a device for detecting blood clots in an extracorporeal blood circulation is proposed, the device optionally comprising an actuator which can create an adjustable constriction on the extracorporeal blood circulation in that it reduces the cross section of a section of a blood line, at least one sensor, which requires at least one parameter related to a property of the liquid in the extracorporeal blood circulation, and a control unit, which is configured such that a measurement signal from the at least one sensor is evaluated, and, that on the basis of this evaluation of the parameter measured by the sensor, the passage of a blood clot through the constriction and / or the sticking of a blood clot in the constriction can be detected.

Disclosed are systems for a body-fluid (e.g., blood) treatment. A blood treatment system comprises a reservoir for holding a batch of blood from a patient; a first conduit for conveying blood from a vascular access of the patient during a first stage and for returning treated blood to the vascular access during a third stage, the first conduit having only a single lumen; a filter for performing extracorporeal treatment on blood passing therethrough by removing waste molecules and / or fluid; a recirculating blood processing loop connecting the reservoir to the filter; a first blood pump for conveying blood in the recirculating blood processing loop; and a controller configured to control the first blood pump to repeatedly recirculate blood from the reservoir through the filter during a second stage between the first and third stages.

The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.

A cannula fixation device includes a base having a platform; a subject-interface portion having an upper surface and a lower surface, the upper surface coupled to the base and the lower surface configured to be coupled to a subject; and a clip assembly configured to retain a portion of a cannula. The clip assembly is moveably coupled to the base such that the clip assembly can be selectively positioned in a first position relative to the base or a second position relative to the base.

The invention relates to devices, systems, and methods for calculating a bicarbonate concentration in a fluid used in dialysis. The devices, systems, and methods can be used to calculate the bicarbonate concentration in either dialysate or blood. The invention measures the amount of carbon dioxide in both an acidified and non-acidified solution and calculates the bicarbonate concentration based on the difference in carbon dioxide concentrations.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.