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Pharmaceutical preparation ingested via nose for treating ischemia cerebrovascular disease

A technology for cerebrovascular diseases and pharmaceutical preparations, applied in the field of treatment of ischemic cerebrovascular diseases, can solve problems such as inconvenient use and various adverse reactions

Inactive Publication Date: 2007-09-12
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Injections require special drug delivery equipment, which is inconvenient to use and prone to various adverse reactions

Method used

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  • Pharmaceutical preparation ingested via nose for treating ischemia cerebrovascular disease
  • Pharmaceutical preparation ingested via nose for treating ischemia cerebrovascular disease
  • Pharmaceutical preparation ingested via nose for treating ischemia cerebrovascular disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Nasal drops: get 20 g of total flavonoids of Pueraria lobata root (purity greater than 60%), add 30 ml of propylene glycol and 50 ml of normal saline to dissolve. Filter, add physiological saline to 100ml from the filter, pack in aliquots, and obtain.

Embodiment 2

[0075] Spray: Take 20g of puerarin, add 50ml of propylene glycol, and 150ml of normal saline to dissolve. Filter, add physiological saline to 200ml from the filter, and pack it into a spray bottle for nasal cavity administration, to obtain.

Embodiment 3

[0077] Nasal powder: pulverize puerarin and sieve. Take 8g of puerarin fine powder with a particle size of 40-60μm, add 2g of microcrystalline cellulose, mix well, and obtain. A total of 10 g of nasal powder was prepared.

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Abstract

The invention relates to a medicinal preparation containing kudzuvine root effective composition and its use in treating cerebrovascular diseases through nose administration, wherein the medicinal composition uses kudzuvine root active ingredient extract as active component, which combines medicinal findings to form various nose administration preparation i.e. nasal drops, spray, nose powder, film dose, gelling agent preparation or emulsion. The preparation can be applied for effectively preventing and treating cerebrovascular diseases.

Description

technical field [0001] The invention relates to a preparation of active ingredients of traditional Chinese medicine, in particular to a pharmaceutical preparation containing the active ingredients of kudzu root, and the application of the drug in treating ischemic cerebrovascular diseases through nasal administration. technical background [0002] Cerebrovascular disease is a frequently-occurring and common disease in humans. There are many types of cerebrovascular diseases, the common ones are cerebral atherosclerosis, cerebral insufficiency, transient ischemic attack, stroke (including subarachnoid hemorrhage, cerebral hemorrhage, and cerebral infarction), hypertensive encephalopathy, and cerebrovascular disease. Sexual dementia, etc. Among them, stroke is one of the three major causes of death among urban and rural residents. With the development of medicine, although the mortality rate of cerebrovascular disease has decreased, it is still one of the main diseases that ...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K36/00A61K9/00A61P9/10
Inventor 张彤徐莲英周飞陶建生蔡贞贞陈长勋徐培康
Owner SHANGHAI UNIV OF T C M
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