Chinese medicinal compsns. for treating postpartum disease

A postpartum disease and composition technology, which is applied in the field of traditional Chinese medicine composition, can solve the problems of insignificant drug efficacy, poor drug stability, rough preparation, etc., and achieve the effects of accelerating body recovery, no toxic side effects, and reasonable prescriptions

Inactive Publication Date: 2007-10-03
JILIN AODONG GRP LIYUAN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Now there are many medicines used to treat postpartum blood loss, blood stasis and other diseases, such as: Chanfukang Granules, Duzhong Granules, etc. In clinical application, most of these medicines have insignificant curative effects, rough preparations, difficult quality control, poor drug stability, etc. The reason is that it cannot occupy the market for a long time. It can be seen that Chinese patent medicines are still relatively blank in the postpartum treatment market for incomplete uterine involution. Therefore, the market urgently needs to develop a treatment for postpartum diseases with definite and significant curative effect, sophisticated technology and stable drug quality. traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0117] The prescription of the composition of the present invention:

[0118] Astragalus 1000g Ejiao 180g Motherwort 1000g

[0119] Peach kernel (fried) 300g Angelica 400g Artemisia argyi 200g

[0120] Preparation:

[0121] For the above six flavors, add donkey-hide gelatin and add water to melt for later use;

[0122] Add 10-16 times the volume of Astragalus membranaceus and Motherwort and decoct 2 or more times, at least 0.5 hours each time, combine the decoction, filter, and concentrate under reduced pressure to a thick paste with a relative density of 1.30-1.35 (60°C). Ointment spare;

[0123] Distillation and extraction of volatile oil from angelica, peach kernel, and mugwort leaves (1-6 hours), and inclusion with β-cyclodextrin for later use; the specific inclusion method is: dilute the volatile oil with 1-3 times the volume of ethanol, and then weigh the volatile oil equivalent to 6 - 10 times the amount of β-cyclodextrin, add water according to the ratio of β-cyclo...

Embodiment 2

[0135] Prescription: astragalus 1470g donkey-hide gelatin 35g motherwort 1470g

[0136] 35g peach kernels 35g angelica leaves 35g

[0137] Preparation method: the preparation of the composition is the same as in Example 1;

[0138] Capsules: After mixing the above-mentioned water decoction paste and donkey-hide gelatin paste, add dextrin and other binders, mix well, place at 60-80°C for vacuum drying, pulverize, mix with β-cyclodextrin inclusion complex, add starch The filling agent is granulated and packed into capsules to obtain the capsules of the present invention.

[0139] The result shows: the composition capsule of the present invention meets relevant regulations under the capsule item.

[0140] Qualitative and quantitative detection are the same as in Example 1.

[0141] This product contains astragaloside IV 0.48mg / g.

Embodiment 3

[0143] Prescription: astragalus 700g donkey-hide gelatin 150g motherwort 500g

[0144] 350g of peach kernels, 690g of angelica, 690g of mugwort leaves

[0145] Preparation method: the preparation of the composition is the same as in Example 1;

[0146] Tablet: After mixing the extracts of the above-mentioned composition of the present invention, add binders such as dextrin, mix thoroughly, place at 60-80°C for vacuum drying, pulverize, add fillers such as starch, lubricants such as magnesium stearate, and Disintegrants such as sodium carboxymethyl cellulose are mixed, granulated, and compressed into tablets to obtain the tablet of the present invention.

[0147] The result shows: the composition tablet of the present invention meets relevant regulations under the tablet item.

[0148] Qualitative and quantitative detection are the same as in Example 1.

[0149] Astragaloside IV (C 41 h 68 o 14 ), the content is 0.41 mg / g.

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Abstract

A Chinese medicine for treating puerperal diseases of woman is prepared from astragalus root, donkey-hide gelatin, motherwort, peach kernnel, and Chinese angelica root and argyi leaf.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, specifically, a traditional Chinese medicine composition for treating postpartum anemia, blood stasis and other diseases. The components of the composition can be Chinese medicinal materials and / or Chinese medicine extract obtained by extraction. Background technique [0002] Maternal postpartum disease is a common and frequently-occurring disease in gynecology. It mainly manifests as postpartum lochia, incomplete uterine involution, postpartum blood loss, blood stasis and other symptoms. Chinese medicine belongs to Qi and blood deficiency and blood stasis syndrome, and Western medicine belongs to postpartum uterine involution. Category, symptoms of postpartum lochia overdue, continuous dripping, astringent, stagnant, frequent volume, dull and lumpy color, no odor, empty lower abdomen, pain, fatigue, pale complexion, dull tongue or petechiae, The pulse is weak, stringy or deep, etc.,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61K36/533A61K36/481A61K36/282A61K36/232A61K35/36A61K9/00A61P15/00A61P7/06
Inventor 程丽芳贾元印王树堂刘同彦陈志国
Owner JILIN AODONG GRP LIYUAN PHARM CO LTD
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