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Medicine for treating muscular dystrophy and myasthenia gravis, and its prepn. method

A technology for myasthenia gravis and muscle atrophy, which is used in drug combinations, pharmaceutical formulations, muscular system diseases, etc. It can solve the problem of intravenous drip and acupoint injection of astragalus injection to strengthen the spleen and kidney, and external washing formula to fumigate and wash the upper limbs to remove phlegm and relieve phlegm. In addition to acupuncture, massage, diet, emotion and other treatments, certain curative effects have also been achieved, but problems such as unsatisfactory effects have been obtained.

Active Publication Date: 2007-12-12
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Professor Li Renxian believes that the disease is based on the deficiency of the spleen and kidney, the internal movement of the deficiency wind is the standard, and there are pathological factors of poor blood vessels. Modified Spleen and Kidney Recipe has achieved certain curative effect; Professor Deng Tietao believes that ALS syndrome is spleen and kidney yang deficiency with phlegm and blood stasis, so he uses Buzhong Yiqi Decoction for oral administration, and intravenous infusion and acupoint injection of Astragalus Injection to strengthen the spleen and kidney , fumigation and washing of the upper limbs with external washing method to remove phlegm and dredging collaterals, enema to expel accumulated stools, supplemented by acupuncture, massage, diet, emotion and other treatments, also achieved certain curative effects, but none of them were satisfactory

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 5 parts ginseng, 2 parts epimedium

[0027] Preparation:

[0028] 1), take the above-mentioned Chinese herbal medicines, select and clean respectively, pulverize, and weigh according to the prescription amount;

[0029] 2), take ginseng medicinal material, extract 3 times with 70% ethanol, add 10 times the amount of solvent extraction of the medicinal material for 1 hour for the first time, add 8 times the amount of solvent extraction for 1 hour for the second time, add 8 times the amount of solvent extraction for 0.5 times for the third time hours; combine the above extracts, filter while hot, concentrate under reduced pressure, put them in a stainless steel bucket, add pure water to stir evenly, and refrigerate for 24 hours; take out the refrigerated solution, put it at room temperature, filter it with a plate and frame filter, and wash with a small amount of water Plate and frame, dilute the filtrate with pure water, and set aside; take the concentrated ginseng liqu...

Embodiment 2

[0034] 5 parts ginseng, 5 parts epimedium

[0035] Preparation method: Same as 1), 2) and 3) steps in Example 1 and make capsules according to conventional methods.

Embodiment 3

[0037] 9 parts of ginseng, 7 parts of epimedium

[0038] Preparation method: Same as 1), 2) and 3) steps in Example 1 and make tablets according to conventional methods.

[0039] The medicine of the present invention is based on the theory of traditional Chinese medicine, adopts the principle of "supporting the vitality and atrophy, nourishing the vitality and promoting muscle growth" as the treatment principle, combined with many years of clinical drug experience, and is designed to treat the disease caused by motor neuron disease (amyotrophic lateral sclerosis) , progressive spinal muscular atrophy, progressive bulbar palsy, primary lateral sclerosis), progressive muscular dystrophy, congenital myopathy, etc. new preparations of traditional Chinese medicine.

[0040] Taking a comprehensive view of the drug prescription of the present invention, a small amount of sweet and warm Epimedium is added to the sweet and flat ginseng, so that the whole prescription is beneficial to ...

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PUM

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Abstract

A Chinese medicine for treating the myophagism and myasthenia gravis caused by motor neuron diseases, prograssive myodystrophy and congenital myopathy is prepared from ginseng and epimedium. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a medicine for treating muscle atrophy and myasthenia gravis and a preparation method thereof, belonging to the technical field of Chinese herbal medicine preparations. Clinically, it is mainly used for motor neuron diseases (amyotrophic lateral sclerosis, progressive spinal muscular atrophy, progressive bulbar palsy, primary lateral sclerosis), progressive muscular dystrophy, congenital myopathy and other diseases. Muscle atrophy and myasthenia gravis. Background technique [0002] Motor neuron disease (motor neuron disease, MND) includes amyotrophic lateral sclerosis (ALS), progressive spinal muscular atrophy, progressive bulbar palsy, primary lateral sclerosis, etc. It is caused by extensive degeneration of neurons, and its symptoms include muscle weakness and muscle atrophy, and gradually develop into eating and drinking cough, dysphagia, dyspnea, and even death. ALS is a chronic progressive degenerative disease of unknow...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/296A61K36/258A61P21/04
Inventor 吴以岭
Owner SHIJIAZHUANG YILING PHARMA
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