Chrisma for vaginal containing tioconzole and its preparation method
A technology of tioconazole and ointment, applied to vaginal ointment containing tioconazole and its preparation, in the field of medicine, can solve the problems of difficulty in grasping technical control points and high cost, and achieves easy implementation of the production process, small systemic absorption, and high cost. powerful effect
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Embodiment 1
[0016] formula:
[0017] Tioconazole 300mg
[0018] Vaseline 3500mg
[0019] Liquid paraffin 500mg
[0020] Ethylparaben 0.1mg
[0021] Preparation:
[0022] The tioconazole is crushed to a powder between 10 μm and 50 μm, mixed with the formulated amount of vaseline and liquid paraffin, and stirred evenly, and finally ethylparaben is added and stirred evenly.
Embodiment 2
[0024] formula:
[0025] Tioconazole 300mg
[0026] White petrolatum 4000mg
[0027] Liquid paraffin 300mg
[0028] BHA 0.1mg
[0029] Preparation:
[0030] Grind tioconazole to a powder between 10 μm and 50 μm, mix and stir evenly with the formula amount of white petrolatum and liquid paraffin, and finally add BHA (tert-butyl-4-hydroxyanisole) and stir evenly.
Embodiment 3
[0032] formula:
[0033] Tioconazole 300mg
[0034] Vaseline 4300mg
[0035] Ethylparaben 0.1mg
[0036] Preparation:
[0037] The tioconazole is ground to a powder between 10 μm and 50 μm, mixed with the formulated amount of petrolatum and stirred evenly, and finally ethylparaben is added and stirred evenly.
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