Mid-pregnancy down's syndrome prenatal screening reagent kit

Abstract

The mid-pregnancy complex screening agent box comprises the AFP standard, AFP single crone anti body wrapped plate bar, AFP quality control, AFP enzyme conjugates, beta -HCG standard, beta -HCG single crone antibody wrapped plate bar, beta -HCG quality control, beta -HCG enzyme conjugates, sample dilute solution, dense cleansing solution, light emitting bottom solution, plate seal film, plate frame, inspecting the AFP or beta -HCG of the pregnant woman, using special data analysis treatment software, with accuracy, reliability, free from trauma, with wide promotion value.

Description

technical field [0001] The invention relates to a kit for prenatal screening of Down's syndrome in the second trimester, which belongs to the field of medical and biological detection. Background technique [0002] Down's syndrome, also known as Trisomy 21 or Down's Syndrome (DS), is the most common congenital defect that causes mental retardation. Its incidence rate is about 1 / 750. Its main features are Severe mental retardation, the IQ is mostly 20-60, only 1 / 4-1 / 2 of normal people of the same age, with small head, flat occiput, thick nape, small eye cleft, upward slant on the outside, deep inner canthus, and distance between the eyes Symptoms such as wide, saddle nose, often half-open mouth, tongue often outside the mouth, short and thick fingers, palm lines running through, little finger inward, etc. The occurrence is accidental and random, and the incidence rate will increase with the increase of pregnant women's age , there is currently no effective treatment for this...

AI Technical Summary

Problems solved by technology

[0002] Down's syndrome, also known as Trisomy 21 or Down's Syndrome (DS), is the most common congenital defect that causes mental retardation. Its incidence rate is about 1 / 750. Its main features are Severe mental retardation, the IQ is mostly 20-60, only 1 / 4-1 / 2 of normal people of the same age, with small head, flat occiput, thick nape, small eye cleft, upward slant on the outside, deep inner canthus, and distance between the eyes Symptoms such as wide, saddle nose, often half-open mouth, tongue often outside the mouth, short and thick fingers, palm lines running through, little finger inward, etc. The occurrence is accidental and random, and the incidence rate will increase with the increase of pregnant women's age , there is currently no effective treatment for this disease. The way to prevent this kind of disease is to carry out prenatal screening and necessary prenatal diagnosis during pregnancy, find out as early as possible and take corresponding measures. At present, clinical prenatal diagnosis The method mainly adopts chorionic villus sampling or amniocentesis for prenatal diagnosis. These methods play a certain role in prenatal detection of fetuses with Down syndrome and preventing the birth of such fetuses. However, amniocentesis is traumatic to a certain extent. , can cause miscarriage, and it is impossible to directly detect all pregnant women with a diagnostic method on a large scale. In addition, certain technical equipment is required, it takes a long time and costs a lot, and it is impossible to widely carry out in all pregnant women. Secondly, even some high-risk pregnant women with indications for amniocentesis refuse to accept amniotic fluid chromosome examination due to the fear that amniocentesis may cause miscarriage. Therefore, the number of births with Down syndrome is still relatively high