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Externally used Chinese traditional medicine emulsion preparations having antibiotic effect and method for preparing the same

A technology for emulsions and antibiotics, which is applied to medical preparations containing active ingredients, anti-infectives, and pharmaceutical formulas, etc. It can solve the problem of adding too much volatile oily ingredients, failing to reach the effective concentration of the drug, and failing to achieve the killing effect, etc. problems, to achieve the effects of not easy to break emulsion, enhance the therapeutic effect, and increase the bactericidal effect

Inactive Publication Date: 2008-01-30
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for some diseases, such as some ringworm, the cure is poor, and continuous medication is required.
The inventor believes that the reason for this situation is that the drug has not reached the effective concentration, and it only has an inhibitory effect on some pathogenic bacteria, but does not achieve a killing effect.
However, the oil-in-water disinfectant cannot increase the content of active ingredients of the drug without limit. If too much volatile oily ingredients are added, the performance of the prepared emulsion is unstable, and it is easy to break the emulsion and cause oil-water separation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] formula:

[0044] borneol 5Kg mint ice 3Kg clove oil 2L paeonol oil 1.5L

[0045] Perrin Oil 1.5L Nepeta Oil 1L Mugwort Oil 0.5L 95% Ethanol 40L

[0046] Tween 801.5L water 50L;

[0047] Preparation:

[0048] a. Take cloves, paeonol, perrin, schizonepeta and mugwort leaves, extract the volatile components of clove oil, paeonol oil, perrin oil, nepeta oil and mugwort leaves respectively by water extraction, and set aside;

[0049] B, take the borneol of formula quantity, mint ice, be dissolved in ethanol;

[0050] c, measure clove oil, paeonol oil, perrin oil, catmint oil, mugwort oil and water of formula quantity, mix with the solution gained in step a, stir evenly;

[0051] d. Add Tween 80 in the formula amount into the mixed solution, and emulsify to obtain the target product (yellow translucent emulsion).

Embodiment 2

[0053] formula:

[0054] Borneol 3.5Kg Peppermint ice 3.5Kg Clove oil 2.5L Danpi oil 1L

[0055] Perrin Oil 1L Nepeta Oil 1.5L Mugwort Oil 0.8L 90% Ethanol 30L

[0056] Span 80 0.8L water 50L;

[0057] The preparation method is the same as in Example 1.

Embodiment 3

[0059] formula:

[0060] Borneol 4Kg Mint ice 4Kg Clove oil 2L Paeonol oil 1L

[0061] Perrin Oil 1L Nepeta Oil 1L Mugwort Oil 0.75L 95% Ethanol 40L

[0062] Tween 80 1L water 50L;

[0063] The preparation method is the same as in Example 1.

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PUM

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Abstract

The present invention discloses a traditional Chinese medicine externally applied emulsion preparation with the antibiotic efficacy, which is mainly composed of borneol, mint ice, clove oil, tree peony bark oil, fortune eupatorium herb oil, fineleaf schizonepeta herb oil, argy wormwood leaf oil, ethanol, emulsifier and water. All the active ingredients are prepared into the water-in-oil emulsion by the emulsifier. The present invention has significant efficacy, fast efficiency and high cure rate for the diseases on the surface of the body which are caused by pathogenic microorganisms and other reasons.

Description

technical field [0001] The invention relates to an externally-used emulsion preparation of traditional Chinese medicine with antibiotic effect and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] At present, the clinical treatment of body surface diseases caused by pathogenic microorganisms and other reasons mainly relies on antibiotics and hormone drugs. However, due to the relatively large side effects of antibiotics and hormonal drugs on the human body, it is necessary to seek a drug that the body will not develop resistance to, can kill a variety of pathogenic bacteria, and can quickly restore damaged skin and mucous membranes. It is one of the efforts of those skilled in the art to replace or reduce the application of antibiotics and hormone drugs. [0003] The inventor once disclosed a kind of traditional Chinese medicine skin disinfectant in the patent document whose publication number is CN 1121871C,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/107A61P17/00A61P31/00A61K31/045
Inventor 韩星温时光刚葛树建郭晓燕李金华郑汉民
Owner SHANDONG PROVINCIAL HOSPITAL
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