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A blood circulation assistance device

A technology of auxiliary devices and blood vessels, which is applied in the direction of circulatory assist devices, blood pumps, control devices, etc., and can solve problems such as aortic injury

Inactive Publication Date: 2008-02-13
卡迪亚克有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This reaction force may move the counterpulsator device relative to the aorta, causing aortic injury

Method used

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  • A blood circulation assistance device
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Examples

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example 1

[0206] This data was obtained in a porcine counterpulsation model of an acute attack using the energy converter described in WO-A-02 / 24254 and a prototype cuff having the design shown in FIG. 18 . The potency of the prototype device is relative to the 40cm 3 The intra-aortic balloon was evaluated.

[0207] Arterial blood pressure and ultrasound cannulated arterial blood flow in the proximal left anterior descending aorta were continuously monitored. Use a peri-aortic cuff as shown in Figure 18. Two cuff variants with expansion elements of length 5 cm and 9 cm were chosen.

[0208] It was found that for both the 5cm and 9cm variants, the increase in diastolic pressure was comparable to the intra-aortic balloon (see Figure 19). It was found that the afterload drop was comparable to, if not better than, the intra-aortic balloon. For example, a peri-aortic cuff with a length of 5 cm reduced end-diastolic blood pressure by 10 mmHg compared to an intra-aortic balloon. The exemp...

example 2

[0211] To achieve the design specification criteria detailed above, experimental model studies were performed. The preferred embodiment of the present invention has a dual inflatable element peri-aortic cuff which therefore has more symmetrical longitudinal aortic stress and strain characteristics and lower peak cyclic excursion of the aortic wall induced by the pump. This has theoretical benefits both in terms of the rate of change of aortic blood volume flow with respect to time (dQ / dt), which is critical to the clinical efficacy of a counterpulse device, and in terms of mechanical fatigue of the aorta. Judgments based. However, an important question is whether there is an additional benefit to increasing the number of expansion elements from two to a larger value. Our research suggests no.

[0212] 30-33 are cross-sectional views of models representing the aorta in the center of the peri-aortic cuff (ie, where the aortic deformation is greatest). These were obtained by a...

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Abstract

A blood circulation assistance device (1) comprises one or more cuff elements (3) which define a chamber for receiving a blood conduit (6). The chamber is open at both ends of the one or more cuff elements (3) for the blood conduit (6) to extend therethrough. There is an aperture (22) in the side of the one or more cuff elements (3) between each end of the chamber for locating the one or more cuff elements (3) about the blood conduit (6). The one or more cuff elements (3) bear two inwardly expanding inflatable elements (4, 5) for compressing the blood conduit (6). The inflatable elements (4, 5) are disposed diametrically opposite each other across the chamber.

Description

technical field [0001] The invention relates to a blood circulation assisting device and method for implementing counterpulsation, especially diastolic counterpulsation. Background technique [0002] Mechanical circulatory support is increasingly used in the management of heart failure. Specifically, ventricular assist devices (VADs) that are configured identically to the heart's own ventricles can provide the potential for heart transplantation (bridge to transplantation) 1 or restore natural myocardial function (bridge to recovery) 2 patients with hemodynamic assistance. More recently, VADs have been considered for heart transplantation (intentional treatment, permanent use) 3 substitute. total artificial heart 4 Less widely used than VADs, which require removal of the original heart and design as a bridge to transplantation and for purpose therapy. Since VADs and total artificial hearts require blood contact, continuous anticoagulation is mandatory to minimize the r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/10A61M60/161A61M60/289A61M60/468A61M60/538A61M60/873A61M60/876
CPCA61M2001/122A61M1/1037A61M1/12A61M1/107A61M2205/8243A61M60/161A61M60/289A61M60/538A61M60/468A61M60/876A61M60/873A61M60/148
Inventor 克里斯多佛·鲍尔斯夏洛特·哈里斯阿斯加尔·卡格哈尼克劳斯·阿费尔德克里斯托夫·莱德勒马丁·凯布尔
Owner 卡迪亚克有限公司
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