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Compound medicine for treating diabetes

A diabetes and drug technology, applied in the field of compound drugs for the treatment of diabetes, can solve problems such as the decline in therapeutic effect, achieve the effects of increased treatment costs, simplified drug regimens, and reduced side effects

Inactive Publication Date: 2008-02-20
左仁杰 +4
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The guidelines for the prevention and treatment of diabetes in China pointed out: "Limited to the current medical level, diabetes is still a chronic disease that cannot be cured, especially type II diabetes is a progressive disease, most patients will appear after a period of treatment with a single oral hypoglycemic drug decline in therapeutic effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] The following examples are only to further illustrate the present invention, but not to limit the scope of the present invention.

[0032] One: Examples of the compound drug for treating diabetes formed by compounding berberine intestinal controlled-release microcapsules and glipizide:

[0033] A compound drug for treating diabetes, the compound drug is compounded by berberine intestinal controlled-release microcapsules and glipizide; when the two drugs are compounded, berberine intestinal controlled-release microcapsules are effective 10-90% of the maximum daily dose of berberine and 90-10% of the maximum daily dose of glipizide are mixed and compounded. Method Granulation and tablet compression. The specific embodiment of two kinds of drug compounding is shown in Table 1:

[0034] Table I

[0035]

Example

I

II

The total in the compounded drug

Active ingredient content

one

10% (60mg)

90% (27mg) ...

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PUM

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Abstract

The present invention provides a compound drug for treating diabetes, the compound drug is prepared by berberine intestinal controlled-release microcapsules and a common western medicine for treating diabetes, 10 to 90 percent of the daily maximum dose of the berberine which is the active ingredient in the berberine intestinal controlled-release microcapsules and 90 to 10 percent of the daily maximum dose of the active ingredient of one common western medicine which is chosen randomly for treating diabetes are used for compound preparation. The berberine intestinal controlled-release microcapsules used in the compound drug of the present invention are the effective drug for treating diabetes, and the microcapsule diameter is 35 to 5000 Mum. The present invention provides the compound drug for treating diabetes, which mainly makes use of the complementary synergistic effect of the main drugs to achieve the purpose of reducing the blood glucose. The compound drug of the present invention for treating diabetes has high treatment success rate, less toxicity, fewer side effects and lower dose; furthermore, the present invention can effectively improve the compliance of the medication of the patients, so as to enhance the effect of reducing blood glucose of the drugs treating diabetes.

Description

[0001] One, technical field: the present invention relates to a kind of compound medicine, particularly relate to a kind of compound medicine for treating diabetes. 2. Technical background: [0002] Diabetes is a common endocrine and metabolic disease. With the change of lifestyle and the acceleration of the aging process, the prevalence of diabetes in my country is showing a rapid upward trend, becoming another serious hazard after cardiovascular and cerebrovascular diseases and tumors. Important chronic non-communicable diseases for people's health. It is an acute and chronic complication, especially the complication of chronic disease involving multiple organs, causing disability and high mortality rate, seriously affecting the physical and mental health of patients, and bringing a heavy burden to individuals, families and society. [0003] According to my country's diabetes prevention and control guidelines, at present, the detection rate, awareness rate and control rate of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4375A61K45/06A61K9/52A61K9/20A61K9/48A61P3/10
Inventor 左仁杰刘五一闻京伟陈蕴陈志超
Owner 左仁杰
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