Cephalosporin derivative

A compound and hydrate technology, applied in the field of medicine, can solve the problems of not providing pharmacological activity and drug resistance
CN101190922AActive Publication Date: 2008-06-04JILIN ZHENAO PHARMA CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
JILIN ZHENAO PHARMA CO LTD
Publication Date
2008-06-04

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Abstract

The invention relates to compounds of novel cephalosporin derivatives as well as pharmaceutically acceptable salts, easy hydrolysis ester, isomer, hydrates and hydrates of salts or esters thereof shown in the general formula (1), wherein, R<1>, R<2>, R<3>, R<4>, R<5> and R<6> are defined as the instruction. The invention also relates to the preparation methods of the compounds, medical composition, which contains the compounds, and the application of the compounds in preparation of drugs, which are used for curing and / or preventing diseases caused by viral infection, and pertains to the field of medical technologies.
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Description

1. Technical field

[0001] The present invention relates to new cephalosporin derivatives, their pharmaceutically acceptable salts, their easily hydrolyzed esters, their isomers, their hydrates and the hydrates of their salts or esters, and the preparation methods of these compounds, which contain these The pharmaceutical composition of the compounds and the use of these compounds in the preparation of medicines for treating and / or preventing infectious diseases belong to the technical field of medicine. 2. Background technology

[0002] Cephalosporin antibiotics are widely used in clinical antibacterial drugs and have been developed to the fourth generation. However, due to long-term clinical use, bacteria are resistant to cephalosporin antibiotics, which greatly affects the antibacterial efficacy of cephalosporin antibiotics. In particular, infectious diseases caused by methicillin-resistant Staphylococcus aureus, penicillin-resistant Streptococcus pneumoniae, and drug-resi...

Claims

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